scholarly journals The studies on the active peptide in the skin of Rana rugosa. II. The structure of ranatensin-R, the new ranatensin analogue, and granuliberin-R, the new mast cell degranulating peptide.

1979 ◽  
Vol 27 (2) ◽  
pp. 492-498 ◽  
Author(s):  
TADASHI YASUHARA ◽  
OSAMU ISHIKAWA ◽  
TERUMI NAKAJIMA
Keyword(s):  
Mast Cell ◽  
Active Peptide ◽  
Mast Cell Degranulating

ADP-ribosylation of rho proteins is inhibited by melittin, mast cell degranulating peptide and compound 48/80

1992 ◽  
Vol 226 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Gertrud Koch ◽  
Barbara Habermann ◽  
Christiane Mohr ◽  
Ingo Just ◽  
Klaus Aktories
Keyword(s):  
Mast Cell ◽  
Rho Proteins ◽  
Adp Ribosylation ◽  
Mast Cell Degranulating

Synthetic analogs of mast cell degranulating (MCD) peptide

Peptides 1990 ◽  
1991 ◽  
pp. 746-747
Author(s):  
Angeliki Buku ◽  
Christian Birr ◽  
Diana Gazis
Keyword(s):  
Mast Cell ◽  
Synthetic Analogs ◽  
Mast Cell Degranulating

Mast cell degranulating (MCD) peptide analogs with reduced ring structure

1992 ◽  
Vol 11 (3) ◽  
pp. 275-280 ◽  
Author(s):  
A. Buku ◽  
J. Reibman ◽  
A. Pistelli ◽  
P. Blandina ◽  
D. Gazis
Keyword(s):  
Mast Cell ◽  
Ring Structure ◽  
Peptide Analogs ◽  
Reduced Ring ◽  
Mast Cell Degranulating

scholarly journals Production of eosinophil-rich guinea pig peritoneal exudates

Blood ◽  
1978 ◽  
Vol 52 (1) ◽  
pp. 127-134 ◽  
Author(s):  
SH Pincus
Keyword(s):  
Mast Cell ◽  
Guinea Pig ◽  
Mechanism Of Action ◽  
Intraperitoneal Injection ◽  
Peritoneal Lavage ◽  
Polymyxin B ◽  
H2 Receptor Antagonist ◽  
Large Numbers ◽  
Satisfactory Method ◽  
Mast Cell Degranulating

Abstract A variety of methods for production of eosinophil-rich guinea pig peritoneal exudates were tested in order to procure large numbers of purified eosinophils. Repeated peritoneal lavage with saline did not produce peritoneal eosinophilia, nor did intraperitoneal injection of dextran beads. Mast cell degranulating agents polymyxin B and, to a lesser degree, compound 48/80 produced significant peritoneal eosinophilia after 6–8 wk of weekly intraperitoneal injections (p less than or equal to 0.05). After more than 8 wk of treatment a mean of 52.1 x 10(6) eosinophils comprising an average of 62% of the peritoneal exudate cells was recovered from polymyxin B-treated guinea pigs. However, polymyxin B-induced peritoneal eosinophilia was abolished by pretreatment with the antihistamine diphenhydramine. Metiamide, an H2 receptor antagonist, did not block the production of peritoneal eosinophils. This is a highly satisfactory method for preparing peritoneal eosinophils; however, the mechanism of action remains to be clearly elucidated.

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