scholarly journals Influence of Alkylamides of Glutamic Acid and Related Compounds on the Central Nervous System. II. Syntheses of Amides of Glutamic Acid and Related Compounds, and Their Effects on the Central Nervous System

1971 ◽  
Vol 19 (7) ◽  
pp. 1301-1307 ◽  
Author(s):  
RYOHEI KIMURA ◽  
TOSHIRO MURATA
Author(s):  
H.C. Fibiger

SUMMARY:Nuclei of the extrapyramidal system contain among the highest levels of GABA and its synthesizing enzyme glutamic acid decarboxylase (GA D) in the central nervous system. In recent years the anatomical organization of GABAergic neurons in the extrapyramidal system has been the subject of considerable experimental enquiry. In this note, current knowledge concerning the origin and projections of GABAergic neurons in certain extrapyramidal nuclei is briefly reviewed.


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