scholarly journals Studies on Optically Active Amino Acids. X. Studies on α-Alkyl-α-amino Acids. V. Absolute Configuration of Biochemically Active (-)-α-Methyl-3, 4-dihydroxyphenylalanine

1966 ◽  
Vol 14 (6) ◽  
pp. 579-582 ◽  
Author(s):  
Shiro Terashima ◽  
Kazuo Achiwa ◽  
Shun-ichi Yamada
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Optically Active

scholarly journals Asymmetric Synthesis of Tetrasubstituted α-Aminophosphonic Acid Derivatives

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3202
Author(s):  
Aitor Maestro ◽  
Xabier del Corte ◽  
Adrián López-Francés ◽  
Edorta Martínez de Marigorta ◽  
Francisco Palacios ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biological Activity ◽  
Absolute Configuration ◽  
Strong Dependence ◽  
Structural Similarity ◽  
Optically Active ◽  
Biologically Active ◽  
Chiral Molecules ◽  
Aminophosphonic Acid ◽  
The Past

Due to their structural similarity with natural α-amino acids, α-aminophosphonic acid derivatives are known biologically active molecules. In view of the relevance of tetrasubstituted carbons in nature and medicine and the strong dependence of the biological activity of chiral molecules into their absolute configuration, the synthesis of α-aminophosphonates bearing tetrasubstituted carbons in an asymmetric fashion has grown in interest in the past few decades. In the following lines, the existing literatures for the synthesis of optically active tetrasubstituted α-aminophosphonates are summarized, comprising diastereoselective and enantioselective approaches.

Synthesis and characteristics of ethylenediamine-N,N'-di-S-α-isovalerate and isomers of its cobalt(III) complexes

1982 ◽  
Vol 47 (1) ◽  
pp. 210-216 ◽  
Author(s):  
Milan Strašák ◽  
František Bachratý ◽  
Jaroslav Majer
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Electronic Absorption ◽  
Electronic Absorption Spectra ◽  
Chemical Parameters ◽  
Methyl Group ◽  
Nmr Data ◽  
Physico Chemical ◽  
Natural Amino Acids ◽  
C Nmr

The synthesis and physico-chemical parameters are described of a new complexone based on natural amino acids, viz. ethylenediamine-N,N'-di-S-α-isovalerate (SS-EDDIV). 1H- and 13C-NMR data revealed that the methyl group in the substance are not equivalent. The isomers of the cobalt(III) complex with the asymmetric tetradentate SS-EDDIV ligand were prepared and separated; their characteristics are given. The absolute configuration of two of the five theoretically feasible isomers was determined based on their electronic absorption spectra and circular dichroism data.

scholarly journals Rapid Organocatalytic Chirality Analysis of Amines, Amino Acids, Alcohols, Amino Alcohols and Diols with Achiral Iso(thio)cyanate Probes

2021 ◽  
Author(s):  
Eryn Nelson ◽  
Jeffrey S. S. K. Formen ◽  
Christian Wolf
Keyword(s):  
Amino Acids ◽  
Absolute Configuration ◽  
Rapid Determination ◽  
Amino Alcohols ◽  
Enantioselective Synthesis ◽  
Widespread Occurrence ◽  
Chiral Compounds ◽  
New Methods ◽  
The Absolute

The widespread occurrence and significance of chiral compounds does not only require new methods for their enantioselective synthesis but also efficient tools that allow rapid determination of the absolute configuration,...

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