Development of a Novel High-Throughput Analytical Methodology, Multiple Injection Method, for Quantitative Analysis in Drug Metabolism and Pharmacokinetic Studies Using Liquid Chromatography with Tandem Mass Spectrometry

Yukari Tanaka; Tomoyuki Ohkawa; Hiroyuki Yasui

doi:10.1248/bpb.34.1187

Development of a Novel High-Throughput Analytical Methodology, Multiple Injection Method, for Quantitative Analysis in Drug Metabolism and Pharmacokinetic Studies Using Liquid Chromatography with Tandem Mass Spectrometry

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.34.1187 ◽

2011 ◽

Vol 34 (8) ◽

pp. 1187-1193 ◽

Cited By ~ 3

Author(s):

Yukari Tanaka ◽

Tomoyuki Ohkawa ◽

Hiroyuki Yasui

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Drug Metabolism ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Multiple Injection ◽

Analytical Methodology

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Effects of flow rate on high-throughput quantitative analysis of protein-precipitated plasma using liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.606 ◽

2002 ◽

Vol 16 (6) ◽

pp. 537-543 ◽

Cited By ~ 16

Author(s):

Anthony T. Murphy ◽

Michael J. Berna ◽

Jeffrey L. Holsapple ◽

Bradley L. Ackermann

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Flow Rate ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Sphingolipidomics: High-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry

Methods ◽

10.1016/j.ymeth.2005.01.009 ◽

2005 ◽

Vol 36 (2) ◽

pp. 207-224 ◽

Cited By ~ 428

Author(s):

Alfred H. Merrill Jr. ◽

M. Cameron Sullards ◽

Jeremy C. Allegood ◽

Samuel Kelly ◽

Elaine Wang

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Liquid chromatography tandem mass spectrometry method for the quantitative analysis of ceritinib in human plasma and its application to pharmacokinetic studies

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-014-8125-9 ◽

2014 ◽

Vol 406 (28) ◽

pp. 7389-7396 ◽

Cited By ~ 13

Author(s):

Olivier Heudi ◽

Denise Vogel ◽

Yvonne Y. Lau ◽

Franck Picard ◽

Olivier Kretz

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Tandem Mass Spectrometry ◽

Human Plasma ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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A New High-Throughput Analysis for Drug Metabolism Profiling Using Liquid Chromatography Coupled with Tandem Mass Spectrometry

Drug Research ◽

10.1055/s-0033-1333782 ◽

2013 ◽

Vol 63 (04) ◽

pp. 171-176 ◽

Cited By ~ 4

Author(s):

K. Kusumoto ◽

T. Nagao ◽

T. Ogihara

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Metabolism ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Tandem Mass ◽

High Throughput Analysis ◽

Throughput Analysis

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Quantitative Analysis of Four Catechins from Green Tea Extract in Human Plasma Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry for Pharmacokinetic Studies

Molecules ◽

10.3390/molecules23040984 ◽

2018 ◽

Vol 23 (4) ◽

pp. 984 ◽

Cited By ~ 5

Author(s):

Jeong-Eun Park ◽

Tae-Eun Kim ◽

Kwang-Hee Shin

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Tandem Mass Spectrometry ◽

Ultra Performance Liquid Chromatography ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Tea Extract

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A Novel Method for High Throughput Lipophilicity Determination by Microscale Shake Flask and Liquid Chromatography Tandem Mass Spectrometry

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/1386207311301010007 ◽

2013 ◽

Vol 16 (10) ◽

pp. 817-825 ◽

Cited By ~ 25

Author(s):

Baiwei Lin ◽

Joseph Pease

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Shake Flask ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Novel Method

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Precolumn derivatization of cysteine residues for quantitative analysis of five major cytochrome P450 isoenzymes by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3202 ◽

2007 ◽

Vol 21 (20) ◽

pp. 3234-3244 ◽

Cited By ~ 13

Author(s):

Xiaotao Duan ◽

Xiaoyan Chen ◽

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Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Tandem Mass Spectrometry ◽

Cysteine Residues ◽

Precolumn Derivatization ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2009.06.003 ◽

2009 ◽

Vol 50 (5) ◽

pp. 872-877 ◽

Cited By ~ 19

Author(s):

Jong-Hwa Lee ◽

Young-Ah Woo ◽

In-Chang Hwang ◽

Choong-Yong Kim ◽

Dae-Duk Kim ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Rat Plasma ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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High throughput identification and quantification of 16 antipsychotics and 8 major metabolites in serum using ultra-high performance liquid chromatography–tandem mass spectrometry

Clinica Chimica Acta ◽

10.1016/j.cca.2013.11.024 ◽

2014 ◽

Vol 429 ◽

pp. 51-58 ◽

Cited By ~ 47

Author(s):

Lisbeth Patteet ◽

Kristof E. Maudens ◽

Bernard Sabbe ◽

Manuel Morrens ◽

Mireille De Doncker ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

High Performance ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Identification And Quantification

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Liquid chromatography/tandem mass spectrometry for pharmacokinetic studies of 20(R)-ginsenoside Rg3 in dog

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.1862 ◽

2005 ◽

Vol 19 (6) ◽

pp. 813-817 ◽

Cited By ~ 33

Author(s):

Ke Li ◽

Xiaoyan Chen ◽

Jinghua Xu ◽

Xin Li ◽

Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Ginsenoside Rg3 ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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