scholarly journals Increase in in Utero Exposure to a Migrant, 4,4′-Butylidenebis(6-t-butyl-m-cresol), from Nitrile-Butadiene Rubber Gloves on Brain Aromatase Activity in Male Rats

2010 ◽  
Vol 33 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Kanako Satoh ◽  
Ryouichi Nonaka ◽  
Dai Nakae ◽  
Akio Ogata
Keyword(s):  
In Utero ◽  
Male Rats ◽  
In Utero Exposure ◽  
Aromatase Activity ◽  
Butadiene Rubber ◽  
Nitrile Butadiene Rubber ◽  
Brain Aromatase

Changes in fetal brain aromatase activity following in utero 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in rats

2002 ◽  
Vol 11 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Masahiko Ikeda ◽  
Naomi Inukai ◽  
Tetsuo Mitsui ◽  
Hideko Sone ◽  
Junzo Yonemoto ◽  
...  
Keyword(s):  
Fetal Brain ◽  
In Utero ◽  
Aromatase Activity ◽  
Brain Aromatase ◽  
Tetrachlorodibenzo P Dioxin ◽  
Dioxin Exposure

Effects of in Utero Exposure to Alcohol upon Male Rats

1985 ◽  
Vol 9 (4) ◽  
pp. 355-359 ◽  
Author(s):  
Mahendra Udani ◽  
Stephen Parker ◽  
Judith Gavater ◽  
David H. Van Thiel
Keyword(s):  
In Utero ◽  
Male Rats ◽  
In Utero Exposure

scholarly journals In utero exposure to an AR antagonist plus an inhibitor of fetal testosterone synthesis induces cumulative effects on F1 male rats☆

2010 ◽  
Vol 30 (2) ◽  
pp. 261-270 ◽  
Author(s):  
A.K. Hotchkiss ◽  
C.V. Rider ◽  
J. Furr ◽  
K.L. Howdeshell ◽  
C.R. Blystone ◽  
...  
Keyword(s):  
In Utero ◽  
Cumulative Effects ◽  
Male Rats ◽  
In Utero Exposure ◽  
Testosterone Synthesis

scholarly journals Dysgenesis and Histological Changes of Genitals and Perturbations of Gene Expression in Male Rats after In Utero Exposure to Antiandrogen Mixtures

2007 ◽  
Vol 98 (1) ◽  
pp. 87-98 ◽  
Author(s):  
S. B. Metzdorff ◽  
M. Dalgaard ◽  
S. Christiansen ◽  
M. Axelstad ◽  
U. Hass ◽  
...  
Keyword(s):  
Gene Expression ◽  
In Utero ◽  
Male Rats ◽  
In Utero Exposure ◽  
Histological Changes

Androgens Regulate Brain Aromatase Activity in Adult Male Rats through a Receptor Mechanism*

Endocrinology ◽  
1984 ◽  
Vol 114 (6) ◽  
pp. 2183-2189 ◽  
Author(s):  
CHARLES E. ROSELLI ◽  
JOHN A. RESKO
Keyword(s):  
Adult Male ◽  
Male Rats ◽  
Aromatase Activity ◽  
Brain Aromatase

Effects on developmental landmarks and reproductive capability of 3,3',4,4'-Tetrachlorobiphenyl and 3,3',4,4',5- Pentacholorobiphenyl in offspring of rats exposed during pregnancy

1998 ◽  
Vol 17 (7) ◽  
pp. 365-372 ◽  
Author(s):  
A S Faqi ◽  
P R Dalsenter ◽  
H-J Merker ◽  
I Chahoud
Keyword(s):  
Serum Testosterone ◽  
In Utero ◽  
Male Offspring ◽  
Male Rats ◽  
Ventral Prostate ◽  
In Utero Exposure ◽  
Neonatal Hypothyroidism ◽  
Reproductive Effects ◽  
Pcb 126 ◽  
Daily Sperm Production

1 Pregnant Wistar rats were treated orally with a single dose of 100 mg3,3',4,4'-tetrachlorobiphenyl (PCB 77)/ kg b.w. or 10 mg3,3',4,4',5 pentachlorobiphenyl (PCB 126)/kg b.w. on day 15 of pregnancy. The control rats received peanut oil at the same day. Developmental landmarks were assessed in all offspring rats and reproductive effects of PCB 77 and PCB 126 on male offspring were studied on postnatal day 65 (at puberty) and on postnatal day 140 (at adulthood). 2 The ano-genital distance as well as the ratio anogenital distance to body length was reduced in male pups of the PCB 126 group and the age at vaginal opening was significantly delayed in the female pups. 3 Testis, brain weights and daily sperm production were permanently increased and seminal vesicle weights were decreased in male offspring of the PCB 77 group. In male rats of PCB 126 group, the brain weights were permanently increased and ventral prostate weights permanently reduced. In both PCB groups, however, serum testosterone concentration was reduced only at adulthood. Additionally, the male rats of the PCB 126 group showed alterations in sexual behavior. In these rats the number of mounts with intromissions was significantly increased. 4 The results of this study show that PCB 126 elicits some TCDD-like reproductive effects after in utero exposure, while the reproductive effects of in utero exposure to PCB 77 on male offspring may be attributed to the neonatal hypothyroidism induced by the substance during early fetal development. Further studies using multiple doses and providing thyroid hormone data will be necessary to support this hypothesis.

Molecular and toxicologic research in newborn hypospadiac male rats following in utero exposure to di-n-butyl phthalate (DBP)

Toxicology ◽  
2009 ◽  
Vol 260 (1-3) ◽  
pp. 120-125 ◽  
Author(s):  
Ying-Jian Zhu ◽  
Jun-Tao Jiang ◽  
Long Ma ◽  
Jie Zhang ◽  
Yan Hong ◽  
...  
Keyword(s):  
In Utero ◽  
Male Rats ◽  
In Utero Exposure ◽  
Butyl Phthalate
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