Nuclear Factor-κB/Signal Transducers and Activators of Transcription-1-Mediated Inflammatory Responses in Lipopolysaccharide-Activated Macrophages Are a Major Inhibitory Target of Kahweol, a Coffee Diterpene

Ting Shen; Yung Chul Park; Seong Hwan Kim; Jaehwi Lee; Jae Youl Cho

doi:10.1248/bpb.33.1159

Nuclear Factor-κB/Signal Transducers and Activators of Transcription-1-Mediated Inflammatory Responses in Lipopolysaccharide-Activated Macrophages Are a Major Inhibitory Target of Kahweol, a Coffee Diterpene

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.33.1159 ◽

2010 ◽

Vol 33 (7) ◽

pp. 1159-1164 ◽

Cited By ~ 27

Author(s):

Ting Shen ◽

Yung Chul Park ◽

Seong Hwan Kim ◽

Jaehwi Lee ◽

Jae Youl Cho

Keyword(s):

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Activated Macrophages ◽

Signal Transducers ◽

Signal Transducers And Activators

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Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-κB

Circulation ◽

10.1161/circulationaha.112.112185 ◽

2012 ◽

Vol 126 (4) ◽

pp. 418-429 ◽

Cited By ~ 102

Author(s):

Suresh Kumar Verma ◽

Prasanna Krishnamurthy ◽

David Barefield ◽

Neha Singh ◽

Rajesh Gupta ◽

...

Keyword(s):

Heart Function ◽

Pressure Overload ◽

Nuclear Factor Κb ◽

Interleukin 10 ◽

Nuclear Factor ◽

Signal Transducers ◽

Dependent Inhibition ◽

Transcription 3 ◽

Signal Transducers And Activators

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Faculty Opinions recommendation of Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717952772.793458307 ◽

2012 ◽

Author(s):

Gad Cotter ◽

Olga Milo

Keyword(s):

Heart Function ◽

Pressure Overload ◽

Nuclear Factor Κb ◽

Interleukin 10 ◽

Nuclear Factor ◽

Signal Transducers ◽

Dependent Inhibition ◽

Transcription 3 ◽

Signal Transducers And Activators

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After portal branch ligation in rat, nuclear factor κB, interleukin-6, signal transducers and activators of transcription 3, c-fos, c-myc, and c-junare similarly induced in the ligated and nonligated lobes

Hepatology ◽

10.1002/hep.510290503 ◽

1999 ◽

Vol 29 (5) ◽

pp. 1463-1470 ◽

Cited By ~ 35

Author(s):

Peter Stärkel ◽

Yves Horsmans ◽

Christine Sempoux ◽

Christine De Saeger ◽

Johan Wary ◽

...

Keyword(s):

Interleukin 6 ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Portal Branch ◽

Signal Transducers ◽

Portal Branch Ligation ◽

Transcription 3 ◽

Signal Transducers And Activators

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Astragalus polysaccharide attenuates lipopolysaccharide-induced inflammatory responses in microglial cells: regulation of protein kinase B and nuclear factor-κB signaling

Inflammation Research ◽

10.1007/s00011-015-0798-9 ◽

2015 ◽

Vol 64 (3-4) ◽

pp. 205-212 ◽

Cited By ~ 17

Author(s):

Tao Luo ◽

Jian Qin ◽

Min Liu ◽

Jun Luo ◽

Fang Ding ◽

...

Keyword(s):

Protein Kinase ◽

Inflammatory Responses ◽

Protein Kinase B ◽

Nuclear Factor Κb ◽

Microglial Cells ◽

Nuclear Factor ◽

Astragalus Polysaccharide

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Methanol extracts of Xanthium sibiricum roots inhibit inflammatory responses via the inhibition of nuclear factor-κB (NF-κB) and signal transducer and activator of transcription 3 (STAT3) in murine macrophages

Journal of Ethnopharmacology ◽

10.1016/j.jep.2015.07.038 ◽

2015 ◽

Vol 174 ◽

pp. 74-81 ◽

Cited By ~ 12

Author(s):

Anna Ju ◽

Young-Chang Cho ◽

Sayeon Cho

Keyword(s):

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Signal Transducer ◽

Murine Macrophages ◽

Methanol Extracts ◽

Xanthium Sibiricum ◽

Transcription 3

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Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-κB and inflammatory responses in lung epithelial cells

Clinical & Experimental Immunology ◽

10.1111/j.1365-2249.2006.03285.x ◽

2006 ◽

Vol 147 (2) ◽

pp. 359-369 ◽

Cited By ~ 37

Author(s):

B. Ekstrand-Hammarström ◽

C. Österlund ◽

B. Lilliehöök ◽

A. Bucht

Keyword(s):

Vitamin E ◽

Epithelial Cells ◽

Protein Kinases ◽

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Lung Epithelial Cells ◽

Nuclear Factor ◽

Mitogen Activated Protein Kinases ◽

Lung Epithelial ◽

Mitogen Activated Protein

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Sinensetin Inhibits Interleukin-6 in Human Mast Cell - 1 Via Signal Transducers and Activators of the Transcription 3 (STAT3) and Nuclear Factor Kappa B (NF-κB) Pathways

Natural Product Sciences ◽

10.20307/nps.2017.23.1.1 ◽

2017 ◽

Vol 23 (1) ◽

pp. 1

Author(s):

Hee-Sung Chae ◽

Young-Mi Kim ◽

Young-Won Chin

Keyword(s):

Mast Cell ◽

Interleukin 6 ◽

Nuclear Factor Kappa B ◽

Human Mast Cell ◽

Nuclear Factor ◽

Signal Transducers ◽

Nuclear Factor Kappa ◽

Transcription 3 ◽

Signal Transducers And Activators

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Caffeic acid phenethyl ester attenuates nuclear factor‑κB‑mediated inflammatory responses in M�ller cells and protects against retinal ganglion cell death

Molecular Medicine Reports ◽

10.3892/mmr.2019.10151 ◽

2019 ◽

Cited By ~ 2

Author(s):

Yanwen Jia ◽

Shengqun Jiang ◽

Chen Chen ◽

Guohua Lu ◽

Yang Xie ◽

...

Keyword(s):

Cell Death ◽

Ganglion Cell ◽

Caffeic Acid ◽

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Caffeic Acid Phenethyl Ester ◽

Nuclear Factor ◽

Retinal Ganglion ◽

Retinal Ganglion Cell Death ◽

Ganglion Cell Death

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2,8-Decadiene-1,10-Diol Inhibits Lipopolysaccharide-Induced Inflammatory Responses Through Inactivation of Mitogen-Activated Protein Kinase and Nuclear Factor-κB Signaling Pathway

Inflammation ◽

10.1007/s10753-015-0283-1 ◽

2015 ◽

Vol 39 (2) ◽

pp. 583-591 ◽

Cited By ~ 3

Author(s):

Mi-Sun Kim ◽

Eun-Kyung Ahn ◽

Seong Su Hong ◽

Joa Sub Oh

Keyword(s):

Protein Kinase ◽

Signaling Pathway ◽

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Mitogen Activated Protein Kinase ◽

Nuclear Factor ◽

Mitogen Activated Protein

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Phlorofucofuroeckol B suppresses inflammatory responses by down-regulating nuclear factor κB activation via Akt, ERK, and JNK in LPS-stimulated microglial cells

International Immunopharmacology ◽

10.1016/j.intimp.2015.08.028 ◽

2015 ◽

Vol 28 (2) ◽

pp. 1068-1075 ◽

Cited By ~ 20

Author(s):

Dong-Kyung Yu ◽

Bonggi Lee ◽

Misung Kwon ◽

Nayoung Yoon ◽

Taisun Shin ◽

...

Keyword(s):

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Microglial Cells ◽

Nuclear Factor

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