scholarly journals The Anti-inflammatory Effect of Gigukjiwhangwhangami through the Inhibition of Nuclear Factor-κB Activation in the Peripheral Blood Mononuclear Cells of Patients with Cerebral Infarction

2006 ◽  
Vol 29 (11) ◽  
pp. 2251-2255 ◽  
Author(s):  
Su-Jin Kim ◽  
Hyun-Ja Jeong ◽  
Phil-Dong Moon ◽  
Kang-Min Lee ◽  
Min-Gu Lee ◽  
...  
Keyword(s):  
Cerebral Infarction ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Red Wine Intake Prevents Nuclear Factor-κB Activation in Peripheral Blood Mononuclear Cells of Healthy Volunteers During Postprandial Lipemia

Circulation ◽  
2000 ◽  
Vol 102 (9) ◽  
pp. 1020-1026 ◽  
Author(s):  
Luis Miguel Blanco-Colio ◽  
Mónica Valderrama ◽  
Luis Antonio Alvarez-Sala ◽  
Carmen Bustos ◽  
Mónica Ortego ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Red Wine ◽  
Mononuclear Cells ◽  
Postprandial Lipemia ◽  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

Nuclear factor-κB activation in peripheral blood mononuclear cells in children with sepsis

2007 ◽  
Vol 35 (10) ◽  
pp. 2395-2401 ◽  
Author(s):  
Noriko Hotta ◽  
Takashi Ichiyama ◽  
Masahiro Shiraishi ◽  
Tsuyoshi Takekawa ◽  
Tomoyo Matsubara ◽  
...  
Keyword(s):  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells

Anti-inflammatory effect of photodynamic therapy using guaiazulene and red lasers on peripheral blood mononuclear cells

2020 ◽  
Vol 31 ◽  
pp. 101747
Author(s):  
Ampika Phutim-Mangkhalthon ◽  
Aroon Teerakapong ◽  
Patcharaporn Tippayawat ◽  
Noppawan Phumala Morales ◽  
Supawich Morkmued ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Peripheral Blood Mononuclear ◽  
Blood Mononuclear Cells ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Protective Effect of Yinhua Miyanling Tablet on Lipopolysaccharide-Induced Inflammation through Suppression of NLRP3/Caspase-1 Inflammasome in Human Peripheral Blood Mononuclear Cells

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Jingying Sai ◽  
Lingxin Xiong ◽  
Jingtong Zheng ◽  
Chuangui Liu ◽  
Yanjiao Lu ◽  
...  
Keyword(s):  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Human Peripheral Blood ◽  
Peripheral Blood Mononuclear ◽  
Caspase 1 ◽  
Blood Mononuclear Cells ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Yinhua Miyanling Tablet (YMT), the Chinese formula, has long been administrated in clinical practice for the treatment of acute pyelonephritis and acute urocystitis. In the current study, we aimed to investigate the anti-inflammatory effect of YMTin vitroand to evaluate the association between anti-inflammation and innate immune response. Human peripheral blood mononuclear cells (PBMCs) were isolated using Ficoll density gradient centrifugation and then were stimulated by Lipopolysaccharide (LPS). The differential gene expression of inflammation-related genes after drug administration was assessed using PCR array, and the protein levels of differential genes were measured by ELISA and Western blot. The result showed that YMT significantly inhibited the expression of NLRP3, Caspase-1, and the downstream cytokine IL-1βand suppressed the production of inflammatory mediators TNF-α, IL-6, IL-10, and MCP-1 in a dose-dependent manner compared to the LPS groupP<0.01. The finding indicated that YMT exhibited anti-inflammatory effectin vitroby suppressing the NLRP3/Caspase-1 inflammasome, and that may have therapeutic potential for the treatment of inflammatory diseases.

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