scholarly journals Lovastatin Reduces Nuclear Factor κB Activation Induced by C-Reactive Protein in Human Vascular Endothelial Cells

2005 ◽  
Vol 28 (9) ◽  
pp. 1630-1634 ◽  
Author(s):  
Rong Lin ◽  
Juntian Liu ◽  
Ning Peng ◽  
Guangde Yang ◽  
Weijie Gan ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Nuclear Factor Kappa B ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Nuclear Factor ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Nuclear Factor Kappa

Tumoral C-reactive protein and nuclear factor kappa-B expression are associated with clinical outcome in patients with prostate cancer

2012 ◽  
Vol 10 (2) ◽  
pp. 91-99 ◽  
Author(s):  
Pamela McCall ◽  
Jamie Catlow ◽  
Peter A McArdle ◽  
Donald C McMillan ◽  
Joanne Edwards
Keyword(s):  
Prostate Cancer ◽  
Clinical Outcome ◽  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Nuclear Factor Kappa

C-reactive protein and statins: IL-8 as a molecular link?

2005 ◽  
Vol 108 (6) ◽  
pp. 493-495 ◽  
Author(s):  
Paul E. SZMITKO ◽  
Subodh VERMA
Keyword(s):  
Endothelial Cells ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
C Reactive Protein ◽  
Aortic Endothelial Cells ◽  
Reactive Protein ◽  
Il Interleukin ◽  
Downstream Effects ◽  
Mitogen Activated Protein

CRP (C-reactive protein) has not only emerged as a useful biomarker for cardiovascular disease, but also as a mediator of atherosclerosis. CRP directly activates vascular endothelial cells, amplifying the inflammatory response underlying atherogenesis. The expression of IL (interleukin)-8 appears to serve as one of the downstream effects of CRP. Kibayashi and co-workers in this issue of Clinical Science confirm that CRP induces IL-8 production in human aortic endothelial cells in vitro, via the activation of MAPKs (mitogen-activated protein kinases), an effect that can be inhibited by pitavastatin.

scholarly journals Leptin Induces C-Reactive Protein Expression in Vascular Endothelial Cells

2007 ◽  
Vol 27 (9) ◽  
Author(s):  
Prachi Singh ◽  
Michal Hoffmann ◽  
Robert Wolk ◽  
Abu S.M. Shamsuzzaman ◽  
Virend K. Somers
Keyword(s):  
Endothelial Cells ◽  
Protein Expression ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
C Reactive Protein ◽  
Reactive Protein
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