scholarly journals Studies on the Antioxidant Activity of Lippia citriodora Infusion: Scavenging Effect on Superoxide Radical, Hydroxyl Radical and Hypochlorous Acid

2002 ◽  
Vol 25 (10) ◽  
pp. 1324-1327 ◽  
Author(s):  
Patrícia Valentão ◽  
Eduarda Fernandes ◽  
Félix Carvalho ◽  
Paula Branquinho Andrade ◽  
Rosa Maria Seabra ◽  
...  
2002 ◽  
Vol 25 (10) ◽  
pp. 1320-1323 ◽  
Author(s):  
Patrícia Valentão ◽  
Eduarda Fernandes ◽  
Félix Carvalho ◽  
Paula Branquinho Andrade ◽  
Rosa Maria Seabra ◽  
...  

2002 ◽  
Vol 57 (11-12) ◽  
pp. 1066-1071 ◽  
Author(s):  
Vera Hadjimitova ◽  
Trayko Traykov ◽  
Milka Mileva ◽  
Stefan Ribarov

We studied antioxidant activity of six neuroleptics (chlorpromazine, levomepromazine, promethazine, trifluoperazine and thioridazine) and two antidepressants (imipramine and amitriptyline) in the range of concentration of 10−7−10−4 м. We applied luminol-dependent chemiluminescence to test the ability of these drugs to scavenge the biologically relevant oxygen-derived species: hydroxyl radical, superoxide radical, hypochlorous acid in vitro. We found that the phenothiazines were powerful scavengers of hydroxyl and superoxide radicals. Chlorprothixene, amitriptyline and imipramine had no scavenge activity to the superoxide radical. All drugs showed a moderate scavenger effect on hypochloric anion.


2013 ◽  
Vol 781-784 ◽  
pp. 1689-1693
Author(s):  
Jing Xian Sun ◽  
Hai Ying Yang ◽  
Ping Zhou ◽  
Guang Qiu Zhang ◽  
Gang Du ◽  
...  

The antioxidant activity of Polyrhachis vicina wine extract was investigated: The IC50 of scavenging effect on superoxide radical generated by Pyrogallol autoxidation was 0.37 mg/mL; the maximum scavenging rate was 81.4%. The IC50 of scavenging effect on hydroxyl free radical generated by Fenton reaction was 0.66 mg/mL; the maximum scavenging rate was 91.8%. The IC50 of DPPH· scavenging effect was 0.48 mg/mL; the maximum scavenging rate was 91.4%. The results indicated that Polyrhachis vicina wine extract showed activity both in scavenging free radicals and antioxidation.


1995 ◽  
Vol 61 ◽  
pp. 73-101 ◽  
Author(s):  
Barry Halliwell

The term antioxidant is widely used but rarely defined. One suggested definition is that an antioxidant is 'a substance that, when present at low concentrations compared with those of an oxidizable substrate, significantly delays or prevents oxidation of that substrate'. Many substances have been suggested to act as antioxidants in vivo, but few have been proved to do so. This chapter addresses the criteria necessary to evaluate a proposed antioxidant activity. Simple methods for assessing the possibility of physiologically feasible scavenging of important biological oxygen-derived species (superoxide, hydrogen peroxide, hydroxyl radical, hypochlorous acid, haem-associated ferryl species, radicals derived from activated phagocytes and peroxyl radicals, both lipid-soluble and water-soluble) are presented. Methods that may be used to gain evidence that a compound actually does function as an antioxidant in vivo are discussed.


2002 ◽  
Vol 50 (17) ◽  
pp. 4989-4993 ◽  
Author(s):  
Patrícia Valentão ◽  
Eduarda Fernandes ◽  
Félix Carvalho ◽  
Paula B. Andrade ◽  
Rosa M. Seabra ◽  
...  

2014 ◽  
Vol 38 (8) ◽  
pp. 3688-3698 ◽  
Author(s):  
Huilu Wu ◽  
Yanhui Zhang ◽  
Chengyong Chen ◽  
Jiawen Zhang ◽  
Yuchen Bai ◽  
...  

Three novel structure Ag(i) complexes have been synthesized and characterized. The three ligands and Ag(i) complexes bind to DNA in an intercalation mode. The Ag(i) complexes have stronger ability of antioxidation for hydroxyl radical and superoxide radical.


2012 ◽  
Vol 554-556 ◽  
pp. 891-899
Author(s):  
Xu Yan Zong ◽  
Li Li ◽  
Xu Qiao Feng ◽  
Hui Bo Luo ◽  
Jian Zhou ◽  
...  

Brewer’s spent grain (BSG) protein extracted from BSG was hydrolyzed using Alcalase to produce BSG protein hydrolysate. BSG protein hydrolysate was fractionated by ultrafiltration to obtain brown color BSG peptides. Antioxidant activity of BSG peptides was analyzeded and compared with reduced glutathione (GSH). BSG peptides exhibited 50% of scavenging activities on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, hydroxyl radical, and superoxide radical with concentrations less than 0.8 mg/mL, 0.6 mg/mL and 0.6 mg/mL, respectively. The reducing power of BSG peptides was 0.70 at the concentration of 2.00 mg/mL. 86.30% of the total amount of the BSG peptides purified by gel permeation chromatography was below 2000 Da. Because of its antioxidant activity, stability, nutritive value and low cost, BSG peptides exerts a possibility to use in food or cosmetic products.


2012 ◽  
Vol 40 (1) ◽  
pp. 222 ◽  
Author(s):  
Otakar ROP ◽  
Martin POSOLDA ◽  
Jiri MLCEK ◽  
Vojtech REZNICEK ◽  
Jiri SOCHOR ◽  
...  

During the last century due to the changes in landscape management, in country people’s lives and with intensive fruit-growing the native cultivars of apple fruit trees have been gradually disappearing. The aim of the study was to compare the juices made of native apple cider cultivars. The cultivars-‘Boikovo’, ‘Jadernicka moravska’, ‘Kardinal zihany’, ‘Panenske ceske’, ‘Parmena zlata zimni’, ‘Strymka’ growing in the locality of the Litencicke Hills in the eastern part of the Czech Republic were selected. For comparison, the fruits of commercial ‘Idared’ cultivar were also included. The chemical composition, antioxidant capacity, phenols, flavonoids and ascorbic acid content and the influence of juices on scavenging activity of nitric oxide and hydroxyl radical were measured. The mutual ratio of examined properties which were found, provide information about qualities and possibilities of use of native cultivars. High antioxidant properties characterize the juice of native apple cultivars. In particular, the ‘Strymka’ cultivar contained 2,637.34 mg of AAE (ascorbic acid equivalent) per litre in case of antioxidant capacity. In the juice of this cultivar the value of 144.05 mg of ascorbic acid per litre was recorded. As regards the ‘Panenske ceske’ cultivar, antioxidant capacity was 2,548.38 mg of AAE l-1 and in relation to ascorbic acid, the value was 145.35 mg l-1. Similarly, high values were observed in both cultivars concerning the scavenging effect of apple juices on hydroxyl radical and nitric oxide (the ‘Strymka’ cultivar 16.38% and 19.26%, the ‘Panenske ceske’ cultivar 16.31% and 18.60%).


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