scholarly journals Frequency and Genetic Characterization of Multidrug-Resistant Mutants of Staphylococcus aureus after Selection with Individual Antiseptics and Fluoroquinolones

2002 ◽  
Vol 25 (9) ◽  
pp. 1129-1132 ◽  
Author(s):  
Norihisa Noguchi ◽  
Maki Tamura ◽  
Koji Narui ◽  
Kazunori Wakasugi ◽  
Masanori Sasatsu
Keyword(s):  
Staphylococcus Aureus ◽  
Genetic Characterization ◽  
Multidrug Resistant ◽  
Resistant Mutants

scholarly journals Phenotypic and genetic characterization of multidrug-resistant Staphylococcus aureus in the tropics of Southeast Asia

Microbiology ◽  
2016 ◽  
Vol 162 (12) ◽  
pp. 2064-2074 ◽  
Author(s):  
Siti Norayuni Mohd Zulkeflle ◽  
Yus Amira Yusaimi ◽  
Norio Sugiura ◽  
Koji Iwamoto ◽  
Masafumi Goto ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Southeast Asia ◽  
Genetic Characterization ◽  
Multidrug Resistant ◽  
Phenotypic And Genetic Characterization ◽  
The Tropics

Characterization of sparfloxacin-resistant mutants of Staphylococcus aureus obtained in vitro

2001 ◽  
Vol 18 (2) ◽  
pp. 107-112 ◽  
Author(s):  
Joaquim Ruiz ◽  
Josep M. Sierra ◽  
M.Teresa Jiménez De Anta ◽  
Jordi Vila
Keyword(s):  
Staphylococcus Aureus ◽  
Resistant Mutants

Genetic characterization of two methicillin-resistant Staphylococcus aureus spa type t127 strains isolated from workers in the dairy production chain in Greece

2021 ◽  
Author(s):  
Theodoros Karampatakis ◽  
Panagiotis Papadopoulos ◽  
Katerina Tsergouli ◽  
Apostolos S. Angelidis ◽  
Daniel Sergelidis ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Genetic Characterization ◽  
Food Handler ◽  
Dairy Production ◽  
Whole Genome ◽  
Genome Sequences ◽  
Production Chain ◽  
Methicillin Resistant ◽  
Mrsa Strains

AbstractMethicillin-resistant Staphylococcus aureus (MRSA) constitutes a constant threat for the public health. Aim of the present study was to analyse the whole genome sequences of two MRSA strains belonging to Staphylococcus protein A (spa) type t127 isolated from humans working in two distantly located dairy production farms in Greece.MRSA strains were isolated from the nasal cavity of a food handler in a milk industry in Epirus, northwestern Greece (E-MRSA), and a person working in a cattle farm in Thrace, northeastern Greece (T-MRSA). Whole genome sequences taken using next generation sequencing were analysed for resistance and virulence genes applying various bioinformatic tools.Both isolates were assigned to ST1-IVa-t127 type, and they were transferring genes conferring resistance to tetracycline, β-lactams, and aminoglycosides; T-MRSA was carrying additional genes leading to macrolide, lincosamide and streptogramin B (MLSB) resistance. Both isolates were carrying three plasmid replicon types, rep5, rep7 and rep16, while T-MRSA harboured also rep10 and rep15. E-MRSA carried scn and sak genes which were absent from T-MRSA.In conclusion, the genetic characterization of two unrelated ST1-IVa-t127 MRSA strains isolated from humans in close contact with livestock in Greece can be used as basis for further epidemiological and evolutionary studies.

Genetic characterization of livestock-associated methicillin-resistant Staphylococcus aureus isolated in Greece

2021 ◽  
Author(s):  
Theodoros Karampatakis ◽  
Panagiotis Papadopoulos ◽  
Katerina Tsergouli ◽  
Apostolos S. Angelidis ◽  
Angeliki Melidou ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Genetic Characterization ◽  
Methicillin Resistant

scholarly journals Genetic Characterization of Fluoroquinolone-Resistant Streptococcus pneumoniae Strains Isolated during Ciprofloxacin Therapy from a Patient with Bronchiectasis

2003 ◽  
Vol 47 (4) ◽  
pp. 1419-1422 ◽  
Author(s):  
Adela G. de la Campa ◽  
María-José Ferrandiz ◽  
Fe Tubau ◽  
Román Pallarés ◽  
Federico Manresa ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Genetic Characterization ◽  
Susceptible Strain ◽  
Low Level ◽  
Resistant Strains ◽  
Resistant Mutants ◽  
High Level ◽  
Level Resistance

ABSTRACT Five Spain9V-3 Streptococcus pneumoniae strains were isolated from a patient with bronchiectasis who had received long-term ciprofloxacin therapy. One ciprofloxacin-susceptible strain was isolated before treatment, and four ciprofloxacin-resistant strains were isolated during treatment. The resistant strains were derived from the susceptible strain either by a parC mutation (low-level resistance) or by parC and gyrA mutations (high-level resistance). This study shows that ciprofloxacin therapy in a patient colonized by susceptible S. pneumoniae may select fluoroquinolone-resistant mutants.

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