scholarly journals Inhibitory Effects of Ethaverine, a Homologue of Papaverine, on Monoamine Oxidase Activity in Mouse Brain.

2001 ◽  
Vol 24 (7) ◽  
pp. 838-840 ◽  
Author(s):  
Sang Seon LEE ◽  
Jae Joon LEE ◽  
Mi Jeong CHEONG ◽  
Young Ho KIM ◽  
Youngsoo KIM ◽  
...  
2001 ◽  
Vol 15 (2) ◽  
pp. 167-169 ◽  
Author(s):  
Sang Sun Lee ◽  
Masaaki Kai ◽  
Myung Koo Lee

1968 ◽  
Vol 46 (15) ◽  
pp. 2519-2524 ◽  
Author(s):  
Surendra S. Parmar ◽  
R. C. Arora

Several substituted quinazolone hydrazides were synthesized to investigate their ability to inhibit rat liver mitochondrial monoamine oxidase. The monoamine oxidase activity was measured manometrically as oxygen uptake during oxidative deamination of tyramine. All quinazolone hydrazides, except 2-methyl-3-(3′-benzhydrazide)-4-quinazolone and 2-methyl-6,8-diiodo-3-(4′-phenylacetylhydrazide)-4-quinazolone, inhibited monoamine oxidase activity when used at a final concentration of 3 × 10−4 M. Substitution at position-6 or positions-6 and -8 of the quinazolone nucleus increased enzyme inhibitory power of quinazolone hydrazides. Monosubstituted quinazolone hydrazides exhibited maximum inhibitory effects while disubstitution resulted in a decrease in their ability to inhibit monoamine oxidase.


1964 ◽  
Vol 11 (4) ◽  
pp. 283-290 ◽  
Author(s):  
TAKASHI KOBAYASHI ◽  
TAKURO KOBAYASHI ◽  
JUNZO KATO ◽  
HIROSHI MINAGUCHI

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