scholarly journals Biological Activity and Structural Characterization of Alkaline-Soluble Polysaccharides from the Kernels of Prunus mume SIEB. et ZACC.

1994 ◽  
Vol 17 (3) ◽  
pp. 386-390 ◽  
Author(s):  
Chikaku DOGASAKI ◽  
Hajime MURAKAMI ◽  
Motohiro NISHIJIMA ◽  
Naohito OHNO ◽  
Toshiro YADOMAE ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Prunus Mume

Structural characterization of naphthalene sulfonamides and a sulfonate ester and their in vitro efficacy against Leishmania tarentolae promastigotes

2021 ◽  
Vol 45 (10) ◽  
pp. 4791-4801
Author(s):  
Edward W. Li ◽  
Jade Katinas ◽  
Marjorie A. Jones ◽  
Christopher G. Hamaker
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Leishmania Tarentolae ◽  
Sulfonate Ester

Structural and biological activity analyses of two naphthalene sulfonamides and a naphthalene sulfonate ester.

Structural characterization of a peptoid with lysine-like side chains and biological activity using NMR and computational methods

2013 ◽  
Vol 11 (4) ◽  
pp. 640-647 ◽  
Author(s):  
Ulrich Sternberg ◽  
Esther Birtalan ◽  
Igor Jakovkin ◽  
Burkhard Luy ◽  
Ute Schepers ◽  
...  
Keyword(s):  
Biological Activity ◽  
Computational Methods ◽  
Structural Characterization ◽  
Side Chains

scholarly journals Structural Characterization and Biological Effects of Constituents of the Seeds of Alpinia katsumadai (Alpina Katsumadai Seed)

2012 ◽  
Vol 7 (6) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Joo-Won Nam ◽  
Eun-Kyoung Seo
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Plant Material ◽  
Review Paper ◽  
Biological Effects ◽  
Chemical Constituents ◽  
Oriental Medicine

Alpinia katsumadai Hayata (Zingiberaceae) has been used as an anti-emetic medicine and to treat gastric disorders in Oriental Medicine. Previous phytochemical investigations of this plant have resulted in the isolation of various diarylheptanoids, kavalactones, flavonoids, stilbenes, monoterpenes, and sesquiterpenes. Some of these compounds have antioxidant, anti-emetic, antiviral, and cytoprotective effects. This review paper discusses the structural characterization of the chemical constituents of A. katsumadai, as well as the biological activity of pure constituents of this plant material.

scholarly journals BIOMOLECOLE DA BASIDIOMICETI COME SORGENTE DI POTENZIALI NUOVI FARMACI

2012 ◽  
Author(s):  
Gianluca Nasini
Keyword(s):  
Helicobacter Pylori ◽  
Biological Activity ◽  
Structural Characterization ◽  
Potent Inhibitor ◽  
Ring System ◽  
Spectroscopic Evidence ◽  
X Ray ◽  
Related Compounds

We reported the isolation and structural characterization of a new biogenetical related compounds, produced in cultures by various strains of Basidiomycetes of the genera Armillaria, Laurilia, Clitocybe and Clavicorona . The isolated metabolites are sesquiterpenoids containing the protoilludane ring system and are even correlated with some biological activity and biogenetic steps. We have analyzed the chemistry of the melleolides, sulcatines, tsugicolines and clavilactones. In particular, the spirolaxine, isolated from cultures of Sporotrichum laxum, is active on the bacterium Helicobacter pylori and is a potent inhibitor of angiogenesis. Its structure was determined on the basis of chemical and spectroscopic evidence and confirmed by X-ray analysis.

Structural characterization of the aquaporin inhibitor 2-nicotinamido-1,3,4-thiadiazole

2015 ◽  
Vol 71 (12) ◽  
pp. 1074-1079 ◽  
Author(s):  
Marianne E. Burnett ◽  
Hannah M. Johnston ◽  
Kayla N. Green
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Antimicrobial Agents ◽  
2D Nmr ◽  
Brain Barrier Permeability ◽  
Nmr Techniques ◽  
One Step ◽  
Uv Visible ◽  
The One

Nicotinamides are a class of compounds with a wide variety of applications, from use as antimicrobial agents to inhibitors of biological processes. These compounds are also cofactors, which are necessary components of metabolic processes. Structural modification gives rise to the activities observed. Similarly, 1,3,4-thiadiazoles have been shown to possess antioxidant, antimicrobial, or anti-inflammatory biological activity. To take advantage of each of the inherent characteristics of the two aforementioned functional groups, 2-nicotinamido-1,3,4-thiadiazole, C8H6N4OS, was synthesized. Since defining chemical connectivity is paramount in understanding biological activity, in this report, the structural characterization of 2-nicotinamido-1,3,4-thiadiazole has been carried out using X-ray crystallographic methods. The NMR-derived assignments were made possible by utilizing one- (1D) and two-dimensional (2D) NMR techniques. In addition, UV–Visible and IR spectroscopies, and elemental analysis were used to fully characterize the product synthesized by the one-step reaction between nicotinoyl chloride hydrochloride and 2-amino-1,3,4-thiadiazole. Computational parameters related to blood–brain barrier permeability are also presented.

Biological activity of bis(pyrazolylpyridine) and terpiridine Os(II) complexes in presence of biocompatible ionic liquids

2021 ◽  
Author(s):  
Angelina Petrović ◽  
Dusan Cocic ◽  
Dirk Bockfeld ◽  
Marko N Živanović ◽  
Nevena Nebojša Milivojević ◽  
...  
Keyword(s):  
Biological Activity ◽  
Ionic Liquids ◽  
Structural Characterization ◽  
Chemical Formula ◽  
Tert Butyl

Within this paper is presented the synthesis and structural characterization of three newly synthesized osmium(II) complexes Os1-3, with the chemical formula [OsIILCl2H2O], [L=2,6-bis(5-tert-butyl-1H-pyrazol-3-yl)pyridine (for Os1), 2,6-bis(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)pyridine (for Os2) or 2,2′:6′,2″-terpyridine...

Synthesis of the Novel Compounds 2-Lactosylthio-3-Alkyl/Alkoxythieno[3,2-d]Pyrimidin-4(3H)-Ones

2013 ◽  
Vol 740 ◽  
pp. 465-468
Author(s):  
Qiu Hong Dai ◽  
Quan Bin Liao ◽  
Nian Yu Huang ◽  
Ming Guo Liu
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Heterocyclic Compounds ◽  
The Novel ◽  
Ammonia Water ◽  
Activity Evaluation ◽  
Alcoholysis Reaction

The title compounds 2-lactosylthio-3-alkyl/alkoxythieno [3,2-pyrimidin-4(3H)-ones 5 were synthesized after the alcoholysis reaction of protected 2-lactosylthio-3-alkyl/alkoxythieno [3,2-pyrimidin-4(3H)-ones 4 with the catalyst of ammonia water. The latters were synthesized from the materials ethyl 3-aminothiophene-2-carboxylate 1 and alkyl/arylisothiocyanates through the thiourea intermediaters 2 and heterocyclic compounds 3. Structural characterization of the target compounds were researched and their biological activity evaluation were underway in our laboratories.

New ultrastructural findings about Borrelia burgdorferi by cryofixation, negative staining, thin sectioning and scanning techniques

1990 ◽  
Vol 48 (3) ◽  
pp. 582-583
Author(s):  
S. F. Hayes ◽  
M. D. Corwin ◽  
T. G. Schwan ◽  
D. W. Dorward ◽  
W. Burgdorfer
Keyword(s):  
Lyme Disease ◽  
Borrelia Burgdorferi ◽  
Structural Characterization ◽  
Negative Staining ◽  
Low Speed ◽  
Thin Sectioning ◽  
Ultrastructural Findings

Characterization of Borrelia burgdorferi strains by means of negative staining EM has become an integral part of many studies related to the biology of the Lyme disease organism. However, relying solely upon negative staining to compare new isolates with prototype B31 or other borreliae is often unsatisfactory. To obtain more satisfactory results, we have relied upon a correlative approach encompassing a variety EM techniques, i.e., scanning for topographical features and cryotomy, negative staining and thin sectioning to provide a more complete structural characterization of B. burgdorferi.For characterization, isolates of B. burgdorferi were cultured in BSK II media from which they were removed by low speed centrifugation. The sedimented borrelia were carefully resuspended in stabilizing buffer so as to preserve their features for scanning and negative staining. Alternatively, others were prepared for conventional thin sectioning and for cryotomy using modified procedures. For thin sectioning, the fixative described by Ito, et al.

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