scholarly journals Fractionation of a Differentiated Mouse Leukemia Cell Line by Discontinuous Ficoll-Urografin Density Gradients

1981 ◽  
Vol 6 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Hiroshi Sakagami ◽  
Senwa Unten ◽  
Minoru Takeda ◽  
Ken Takeda ◽  
Kunio Konno
1977 ◽  
Vol 5 (1) ◽  
pp. 295-308 ◽  
Author(s):  
C. Flores ◽  
T. V. Rajan

2012 ◽  
Vol 7 (11) ◽  
pp. 1934578X1200701 ◽  
Author(s):  
Dahai Zhang ◽  
Seketsu Fukuzawa ◽  
Masayuki Satake ◽  
Xianguo Li ◽  
Takafumi Kuranaga ◽  
...  

Two new sesterterpenes, ophiobolin O (1) and 6-epi-ophiobolin O (2), together with the known ophiobolins G (3), H (4), and K (5), and 6-epi-ophiobolin K (6) were isolated from the marine derived fungus Aspergillus sp. The structures of these compounds were elucidated based on chemical and physicochemical evidence, including MS, UV, IR and NMR spectra. The stereochemistry of 1 was further confirmed by catalytic reaction of 5 with p-TsOH as a catalyst. Compounds 1 to 6 showed cytotoxicity against mouse leukemia cell line P388, with IC50 values of 4.7, 9.3, 24.6, 105.7, 13.3 and 24.9 μM, respectively.


1989 ◽  
Vol 164 (3) ◽  
pp. 1397-1401 ◽  
Author(s):  
Toshio Tanaka ◽  
Masatoshi Hagiwara ◽  
Hiroyoshi Hidaka ◽  
Kazuo Nunoki ◽  
Hisataka Ohta ◽  
...  

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