scholarly journals cDNA Cloning and Sequence Analysis of a Novel Calcium Binding Protein with Oligoproline Motif.

1995 ◽  
Vol 20 (4) ◽  
pp. 263-268 ◽  
Author(s):  
Su Yu ◽  
Masayuki Ozawa ◽  
Apala Farhat Naved ◽  
Teruo Miyauchi ◽  
Hisako Muramatsu ◽  
...  
Keyword(s):  
Sequence Analysis ◽  
Cdna Cloning ◽  
Calcium Binding ◽  
Binding Protein ◽  
Calcium Binding Protein

scholarly journals Isolation and characterization of grancalcin, a novel 28 kDa EF-hand calcium-binding protein from human neutrophils

1992 ◽  
Vol 286 (2) ◽  
pp. 549-554 ◽  
Author(s):  
C G Teahan ◽  
N F Totty ◽  
A W Segal
Keyword(s):  
Sequence Analysis ◽  
Calcium Binding ◽  
Binding Protein ◽  
Sequence Similarity ◽  
Gel Filtration ◽  
Calcium Binding Protein ◽  
Peptide Sequence ◽  
Human Neutrophils ◽  
Isolation And Characterization ◽  
Ef Hand

A novel 28 kDa protein, which we have named ‘grancalcin’, has been identified in human neutrophils. The protein was isolated from the cytosol and found to be a homodimer, with an apparent molecular mass of 55 kDa on gel filtration. Polyclonal antibodies were raised to the native protein. N-Terminal sequence analysis and tryptic-peptide sequence analysis was performed. The protein exhibits sequence similarity to sorcin, a 24 kDa calcium-binding protein over-expressed in certain multi-drug-resistant cell lines. It appears to be a member of the EF-hand family of calcium-binding proteins. The association of a high proportion of this protein with the membranes and granules in the presence of physiological concentrations of calcium may indicate a role in granule-membrane fusion and degranulation.

Vitamin-D dependent 9 kDa calcium-binding protein gene: cDNA cloning, mRNA distribution and regulation

Biochimie ◽  
1986 ◽  
Vol 68 (7-8) ◽  
pp. 935-940 ◽  
Author(s):  
Monique Thomasset ◽  
Claude Desplan ◽  
Maryvonne Warembourg ◽  
Christine Perret
Keyword(s):  
Vitamin D ◽  
Cdna Cloning ◽  
Calcium Binding ◽  
Protein Gene ◽  
Binding Protein ◽  
Calcium Binding Protein ◽  
Binding Protein Gene
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