Guanine-Tethered Oligonucleotides Restore Abnormal Protein Synthesis with a SNP Mutation in a 5’-UTR G-quadruplex of Human MSH2

2021 ◽  
Author(s):  
Masaki Hagihara ◽  
Shuhei Shiroto ◽  
Shunya Igarashi ◽  
Shin-ichi Sato
Keyword(s):  
Protein Synthesis ◽  
Abnormal Protein ◽  
G Quadruplex

Inhibition of Protein Synthesis Through RNA-Based Tandem G-Quadruplex Formation

2021 ◽  
Author(s):  
Masaki Hagihara
Keyword(s):  
Protein Synthesis ◽  
Reverse Transcriptase ◽  
Repeat Sequences ◽  
Guanine Quadruplex ◽  
G Quadruplex ◽  
Inhibition Of Protein Synthesis ◽  
Quadruplex Formation

Tandem guanine repeat sequences can adopt guanine quadruplex (G-quadruplex) structures and consecutive guanine repeat sequences can potentially afford multiple G-quadruplex structures. By using a reverse transcriptase stop assay and biophysical...

Abnormal protein synthesis in facioscapulohumeral muscular dystrophy

Neurology ◽  
1972 ◽  
Vol 22 (12) ◽  
pp. 1286-1286 ◽  
Author(s):  
V. Ionasescu ◽  
H. Zellweger ◽  
P. Shirk ◽  
T. W. Conway
Keyword(s):  
Protein Synthesis ◽  
Muscular Dystrophy ◽  
Facioscapulohumeral Muscular Dystrophy ◽  
Abnormal Protein

Homochirality as the Signature of Extra-Terrestrial Life

1997 ◽  
Vol 161 ◽  
pp. 505-510
Author(s):  
Alexandra J. MacDermott ◽  
Laurence D. Barron ◽  
Andrè Brack ◽  
Thomas Buhse ◽  
John R. Cronin ◽  
...  
Keyword(s):  
Amino Acids ◽  
Protein Synthesis ◽  
Optical Rotation ◽  
Physical Origin ◽  
Natural Choice ◽  
Rosetta Mission ◽  
Terrestrial Life ◽  
Subsurface Layers ◽  
Solar System Bodies ◽  
Origin Of Homochirality

AbstractThe most characteristic hallmark of life is its homochirality: all biomolecules are usually of one hand, e.g. on Earth life uses only L-amino acids for protein synthesis and not their D mirror images. We therefore suggest that a search for extra-terrestrial life can be approached as a Search for Extra- Terrestrial Homochirality (SETH). The natural choice for a SETH instrument is optical rotation, and we describe a novel miniaturized space polarimeter, called the SETH Cigar, which could be used to detect optical rotation as the homochiral signature of life on other planets. Moving parts are avoided by replacing the normal rotating polarizer by multiple fixed polarizers at different angles as in the eye of the bee. We believe that homochirality may be found in the subsurface layers on Mars as a relic of extinct life, and on other solar system bodies as a sign of advanced pre-biotic chemistry. We discuss the chiral GC-MS planned for the Roland lander of the Rosetta mission to a comet and conclude with theories of the physical origin of homochirality.

Lymphocyte activity and protein synthesis

2001 ◽  
Vol 101 (6) ◽  
pp. 591
Author(s):  
DEREK C. MACALLAN
Keyword(s):  
Protein Synthesis ◽  
Lymphocyte Activity

Protein synthesis in mitochondria purified from roots, leaves and flowers of sugar beet

1991 ◽  
Vol 83 (1) ◽  
pp. 7-16 ◽  
Author(s):  
Christina Lind ◽  
Christer Hallden ◽  
Ian M. Moller
Keyword(s):  
Protein Synthesis ◽  
Sugar Beet

Respiratory energy requirements and rate of protein turnover in vivo determined by the use of an inhibitor of protein synthesis and a probe to assess its effect

1994 ◽  
Vol 92 (4) ◽  
pp. 585-594 ◽  
Author(s):  
T. J. Bouma ◽  
R. De Visser ◽  
J. H. J. A. Janssen ◽  
M. J. De Kock ◽  
P H. Van Leeuwen ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Protein Turnover ◽  
Energy Requirements ◽  
Inhibitor Of Protein Synthesis

Altered protein synthesis during in situ oat leaf senescence

1990 ◽  
Vol 80 (4) ◽  
pp. 619-623 ◽  
Author(s):  
Louise Lalonde ◽  
Rajinder S. Dhindsa
Keyword(s):  
Protein Synthesis ◽  
Leaf Senescence ◽  
Altered Protein

Age of potato seed-tubers influences protein synthesis during sprouting

1993 ◽  
Vol 89 (2) ◽  
pp. 262-270 ◽  
Author(s):  
G. N. Mohan Kumar ◽  
N. Richard Knowles
Keyword(s):  
Protein Synthesis ◽  
Potato Seed ◽  
Seed Tubers
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