scholarly journals Fabrication of SmCoxNanoparticles as a Potential Candidate of Materials for Super-high-density Magnetic Memory: Use of Gold as the Third Element

2007 ◽  
Vol 36 (10) ◽  
pp. 1264-1265 ◽  
Author(s):  
Toru Matsushita ◽  
Junya Masuda ◽  
Takashi Iwamoto ◽  
Naoki Toshima
Keyword(s):  
High Density ◽  
Magnetic Memory ◽  
Potential Candidate ◽  
The Third

Tuning the Mechanical Properties of High-Density Polyethylene by ECAE Process

2015 ◽  
Author(s):  
Catalin Fetecau ◽  
Felicia Stan ◽  
Laurentiu Sandu ◽  
Florin Susac
Keyword(s):  
Mechanical Properties ◽  
High Density Polyethylene ◽  
Equal Channel Angular Extrusion ◽  
Morphological Changes ◽  
Longitudinal Axis ◽  
High Density ◽  
Scanning Calorimetry ◽  
Plastic Deformations ◽  
The Third ◽  
Indentation Tests

This paper investigates the ability of the equal channel angular extrusion (ECAE) process to induce morphological changes and hence tune the mechanical properties of high-density polyethylene (HDPE). In this study, differential scanning calorimetry (DSC), compression and cylindrical macro-indentation tests have been used to investigate the evolution of the mechanical properties of HDPE processed by ECAE up to four passes via route BC, i.e. counter clockwise 90° billet rotation about its longitudinal axis. It was found that the ECAE process induces significant plastic deformations with changes in the crystalline structure. The ECAE process increased the HDPE crystallinity by 10 to 15%. The number of ECAE passes has a significant effect on the magnitude of the mechanical properties especially on the elastic modulus and yield stress. Young’s modulus and yield strength decreased with increasing the number of ECAE passes and reached a stationary state after the third pass.

The human breast carcinoma cell line HBL-100 acquires exogenous cholesterol from high-density lipoprotein via CLA-1 (CD-36 and LIMPII analogous 1)-mediated selective cholesteryl ester uptake

2000 ◽  
Vol 349 (2) ◽  
pp. 559-566 ◽  
Author(s):  
Pirkko J. PUSSINEN ◽  
Barbara KARTEN ◽  
Andrea WINTERSPERGER ◽  
Helga REICHER ◽  
Mark MCLEAN ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
High Density Lipoprotein ◽  
Cholesteryl Ester ◽  
Density Lipoprotein ◽  
High Density ◽  
Hormone Sensitive Lipase ◽  
Potential Candidate ◽  
Selective Uptake ◽  
Exogenous Cholesterol ◽  
Hormone Sensitive

Aberrant cell proliferation is one of the hallmarks of carcinogenesis, and cholesterol is thought to play an important role during cell proliferation and cancer progression. In the present study we examined the pathways that could contribute to enhanced proliferation rates of HBL-100 cells in the presence of apolipoprotein E-depleted high-density lipoprotein subclass 3 (HDL3). When HBL-100 cells were cultivated in the presence of HDL3 (up to 200 μg/ml HDL3 protein), the growth rates and cellular cholesterol content were directly related to the concentrations of HDL3 in the culture medium. In principle, two pathways can contribute to cholesterol/cholesteryl ester (CE) uptake from HDL3, (i) holoparticle- and (ii) scavenger-receptor BI (SR-BI)-mediated selective uptake of HDL3-associated CEs. Northern- and Western-blot analyses revealed the expression of CLA-1 (CD-36 and LIMPII analogous 1), the human homologue of the rodent HDL receptor SR-BI. In line with CLA-1 expression, selective uptake of HDL3-CEs exceeded HDL3-holoparticle uptake between 12- and 58-fold. Competition experiments demonstrated that CLA-1 ligands (oxidized HDL, oxidized and acetylated low-density lipoprotein and phosphatidylserine) inhibited selective HDL3-CE uptake. In line with the ligand-binding specificity of CLA-1, phosphatidylcholine did not compete for selective HDL3-CE uptake. Selective uptake was regulated by the availability of exogenous cholesterol and PMA, but not by adrenocorticotropic hormone. HPLC analysis revealed that a substantial part of HDL3-CE, which was taken up selectively, was subjected to intracellular hydrolysis. A potential candidate facilitating extralysosomal hydrolysis of HDL3-CE is hormone-sensitive lipase, an enzyme which was identified in HBL-100 cells by Western blots. Our findings demonstrate that HBL-100 cells are able to acquire HDL-CEs via selective uptake. Subsequent partial hydrolysis by hormone-sensitive lipase could provide ‘free’ cholesterol that is available for the synthesis of cellular membranes during proliferation of cancer cells.

scholarly journals Ultra-High-Density QTL Marker Mapping for Seedling Photomorphogenesis Mediating Arabidopsis Establishment in Southern Patagonia

2021 ◽  
Vol 12 ◽  
Author(s):  
Daniel Matsusaka ◽  
Daniele Filiault ◽  
Diego H. Sanchez ◽  
Javier F. Botto
Keyword(s):  
Complex Traits ◽  
Red Light ◽  
High Density ◽  
Potential Candidate ◽  
Hypocotyl Length ◽  
Light Responses ◽  
Wide Range ◽  
Southern Patagonia ◽  
Ril Population ◽  
Wild Accessions

Arabidopsis thaliana shows a wide range of genetic and trait variation among wild accessions. Because of its unparalleled biological and genomic resources, Arabidopsis has a high potential for the identification of genes underlying ecologically important complex traits, thus providing new insights on genome evolution. Previous research suggested that distinct light responses were crucial for Arabidopsis establishment in a peculiar ecological niche of southern Patagonia. The aim of this study was to explore the genetic basis of contrasting light-associated physiological traits that may have mediated the rapid adaptation to this new environment. From a biparental cross between the photomorphogenic contrasting accessions Patagonia (Pat) and Columbia (Col-0), we generated a novel recombinant inbred line (RIL) population, which was entirely next-generation sequenced to achieve ultra-high-density saturating molecular markers resulting in supreme mapping sensitivity. We validated the quality of the RIL population by quantitative trait loci (QTL) mapping for seedling de-etiolation, finding seven QTLs for hypocotyl length in the dark and continuous blue light (Bc), continuous red light (Rc), and continuous far-red light (FRc). The most relevant QTLs, Rc1 and Bc1, were mapped close together to chromosome V; the former for Rc and Rc/dark, and the latter for Bc, FRc, and dark treatments. The additive effects of both QTLs were confirmed by independent heterogeneous inbred families (HIFs), and we explored TZP and ABA1 as potential candidate genes for Rc1 and Bc1QTLs, respectively. We conclude that the Pat × Col-0 RIL population is a valuable novel genetic resource to explore other adaptive traits in Arabidopsis.

scholarly journals Fruiting of High-density Apple Orchards on Clonal Rootstocks

HortScience ◽  
1996 ◽  
Vol 31 (4) ◽  
pp. 665e-665
Author(s):  
A.S. Devyatov
Keyword(s):  
Podzolic Soil ◽  
Tree Density ◽  
High Density ◽  
Annual Precipitation ◽  
Apple Orchards ◽  
Average Yield ◽  
The Third ◽  
Initial Yield ◽  
Nursery Trees ◽  
All Treatment

Orchard densities from 833 to 2500 trees/ha were studied on sod-podzolic soil (annual precipitation 550 mm). An orchard was planted in Spring 1990 and 1991 using 2-year-old nursery trees grown in film containers. The interval between trees in the row was 1 to 1.5 to 2 to 2.5 and 3 m. The trees were grafted on dwarf rootstock (62-396) and semi-dwarf (54-118). The commercial fruiting of `Tellisaare' began the third year after planting, `Antey' the fourth, and Spartan at fifth. The initial yield of `Antey in the most dense treatment was 14.5 t·ha–1, `Tellisaare' was 15 to 22 t·ha–1, according to rootstocks. Average yield of `Antey' on 62-396 for 1992–95 at the orchard density of 2500 trees/ha was 10 t·ha–1·year–1 and on rootstock of 54-118 it was 21 t·ha–1. However, yield of `Tellisaare' 54-118 for 1992–1995 was 13 to 15 t·ha–1 in all treatment of orchard density from 1666 to 833 trees/ha. The annual yield of this cultivar grafted on rootstock 54-118 at a tree density of 2500 plants/ha increased to 18.3 t·ha–1.

scholarly journals Identification of fruit size associated quantitative trait loci featuring SLAF based high-density linkage map of goji berry (Lycium spp.)

2020 ◽  
Author(s):  
Fazal Rehman ◽  
Haiguang Gong ◽  
Zhong Li ◽  
Shaohua Zeng ◽  
Tianshun Yang ◽  
...  
Keyword(s):  
Qtl Mapping ◽  
Linkage Map ◽  
Genetic Map ◽  
De Novo ◽  
Fruit Size ◽  
Leaf Size ◽  
High Density ◽  
Potential Candidate ◽  
Goji Berry ◽  
High Density Linkage Map

Abstract Background: Goji (Lycium spp., 2n = 24) is a perennial woody plant bearing functional properties. Fruit size associated attributes are important for evaluating small-fruited goji berry and plant architecture. The domestication traits are regulated quantitatively in crop plants but fewer studies have attempted on genomic regions corresponding to the fruit traits.Results: In this study, we established high-resolution map using SLAF-seq for de novo SNPs detection, based on 305 F1 offspring derived from L. chinense and L. barbarum. This genetic map contained 3,495 SNP markers on 12 LGs, spanning 1,649.03 cM with 0.47 cM average interval. Female and male parents had sequencing depth of 72.43-fold and 60.43-fold, respectively, while 15.23-fold detected for individuals. Phenotype data were obtained for 2 years and included 3rd year data as an average. QTL mapping analysis resulted in 117 QTLs corresponding to all traits, of which 23 QTLs in 2 years and 6 QTLs in 3rd years were detected. 6 promising QTLs, qFW10-3.1, qFL10-2.1, qLL10-2.1, qLD10-2.1, qLD12-4.1 and qLA10-2.1 were discovered influencing fruit weight, fruit length and leaf size related attributes covering an interval ranged 13.74-76.61 cM on LG10 with peak LOD up to 14.21 and PVE 19.3%. Additionally, 3 QTLs, qFS-1, qFS-2 and qFF-1, targeting fruit sweetness and fruit firmness were also identified in this study. Strikingly, among stable QTLs, qFL10-2.1, was co-localized to qLL10-2.1, qLD10-2.1, qLA10-2.1 and harbored significantly similar markers distribution, while qLL10-2.1 was the major and stable QTL with LOD ranged from 8.71-14.21 and PVE 12.3-19.3%. As LG10 harbored most of the fruit and leaf size related QTLs, we might speculate that it could be a hotspot region regulating fruit size and plant architectures.Conclusions: This report highlighted that the high-density linkage map construction using SLAF-seq is an important means for profound QTL mapping approach. Substantially, we utilized highly saturated genetic map to find out genetic locus targeting fruit and leaf size related attributes under QTL mapping. Our results will shed light on domestication traits and further strengthen molecular and genetic underpinnings of goji berry. Moreover, these findings would facilitate to assemble reference genome, determining potential candidate genes and marker-assisted breeding.

scholarly journals Construction of a high-density genetic linkage map and mapping of quantitative trait loci for growth-related traits in silver carp (Hypophthalmichthys molitrix)

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Xinhua Wang ◽  
Haiyang Liu ◽  
Meixia Pang ◽  
Beide Fu ◽  
Xiaomu Yu ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Linkage Map ◽  
Quantitative Trait ◽  
Genetic Linkage ◽  
Genetic Linkage Map ◽  
Growth Traits ◽  
Silver Carp ◽  
High Density ◽  
Potential Candidate ◽  
Hypophthalmichthys Molitrix

AbstractHigh-density genetic map and quantitative trait loci (QTL) mapping are powerful tools for identifying genomic regions that may be responsible for such polygenic trait as growth. A high-density genetic linkage map was constructed by sequencing 198 individuals in a F1 family of silver carp (Hypophthalmichthys molitrix) in this study. This genetic map spans a length of 2,721.07 cM with 3,134 SNPs distributed on 24 linkage groups (LGs). Comparative genomic mapping presented a high level of syntenic relationship between silver carp and zebrafish. We detected one major and nineteen suggestive QTL for 4 growth-related traits (body length, body height, head length and body weight) at 6, 12 and 18 months post hatch (mph), explaining 10.2~19.5% of phenotypic variation. All six QTL for growth traits of 12 mph generally overlapped with QTL for 6 mph, while the majority of QTL for 18 mph were identified on two additional LGs, which may reveal a different genetic modulation during early and late muscle growth stages. Four potential candidate genes were identified from the QTL regions by homology searching of marker sequences against zebrafish genome. Hepcidin, a potential candidate gene identified from a QTL interval on LG16, was significantly associated with growth traits in the analyses of both phenotype-SNP association and mRNA expression between small-size and large-size groups of silver carp. These results provide a basis for elucidating the genetic mechanisms for growth and body formation in silver carp, a world aquaculture fish.

Damage evaluation and protection method of resin pipe for gas conduit subjected to impact load

2020 ◽  
Vol 11 (4) ◽  
pp. 423-447 ◽  
Author(s):  
Hiroki Tamai ◽  
Sota Jinkawa ◽  
Yoshimi Sonoda
Keyword(s):  
High Density Polyethylene ◽  
Impact Test ◽  
Impact Resistance ◽  
High Density ◽  
Third Party ◽  
Medium Density ◽  
Absorbed Energy ◽  
Polyethylene Pipe ◽  
The Third ◽  
The Impact

Medium-density polyethylene pipe has been widely introduced to low-pressure gas pipes because of its high flexibility and corrosion resistance. However, many third-party damages due to the impact of heavy equipment have been reported during the construction every year, thus, to prevent the third-party damage, materials such as high-density polyethylene and polyamide have been considered as the new gas pipe candidates. However, their impact resistance capacity under the third-party attack has not been clarified. In this study, static and impact loading experiments were conducted to compare load resistance capacities. As a result, it was revealed that the high-density polyethylene pipe and the polyamide pipe had higher static load capacity and impact resistance than the medium-density polyethylene pipe. By comparing the absorbed energy of the static test and the impact test and calculating the pseudo absorbed energy of the impact test, the evaluation formula judging the safer side of whether the penetration occurred was proposed. Furthermore, as one of the methods to protect the gas pipe, the protective effect of winding a sheet made of reinforced fiber and non-woven fabric was clarified.

Familial high-density lipoprotein deficiency (tangier disease): The third Italian case

1988 ◽  
Vol 11 (S2) ◽  
pp. 155-157 ◽  
Author(s):  
G. Bracco ◽  
G. Dotti ◽  
F. Levis ◽  
E. David ◽  
G. Saracco ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Tangier Disease ◽  
The Third ◽  
Italian Case

Thermal and flammability properties of polyethylene composites with fibers to replace natural wood

2021 ◽  
pp. 073168442110028
Author(s):  
Jairo da Silva Rocha ◽  
Viviane A Escócio ◽  
Leila LY Visconte ◽  
Élen BAV Pacheco
Keyword(s):  
Thermal Stability ◽  
Magnesium Hydroxide ◽  
High Density Polyethylene ◽  
Fiber Composite ◽  
Impact Resistance ◽  
High Density ◽  
Potential Candidate ◽  
Lignocellulosic Fiber ◽  
Sponge Gourd ◽  
Natural Wood

Composites of high-density polyethylene and lignocellulosic fiber residues from banana, papaya, and peach palm trees, in addition to sponge gourd and coconut fiber, were investigated to identify the least flammable composite as a potential substitute for natural pine wood. The high-density polyethylene/lignocellulosic fiber composites were prepared in a twin-screw extruder, injection molded to obtain specimens, and characterized in terms of thermogravimetry, flammability using the UL-94 burning test and limiting oxygen index, impact resistance and heat deflection temperature. The high-density polyethylene/sponge gourd fiber composite showed the best impact resistance and was selected for further tests, with the addition of 10wt% magnesium hydroxide and (or) rice husk ash as flame retardants. The use of both retardants provided greater thermal stability to the composite. The addition of magnesium hydroxide to the high-density polyethylene/sponge gourd fiber composite improved the flammability properties of horizontal burning and thermal stability and is a potential candidate to replace natural wood.

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