Site-selective Scission of Double-stranded DNA by Combining Peptide Nucleic Acids and Ce(IV)/EDTA

2004 ◽  
Vol 33 (7) ◽  
pp. 920-921 ◽  
Author(s):  
Yoji Yamamoto ◽  
Makoto Komiyama
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Double Stranded Dna ◽  
Site Selective

Recognition Mechanisms and Applications of Peptide Nucleic Acids Targeting Double-stranded DNA

2016 ◽  
Vol 23 (41) ◽  
pp. 4681-4705 ◽  
Author(s):  
Wenjia Li ◽  
Huanhuan Shi ◽  
Bo Dong ◽  
Kaixuan Nie ◽  
Zhengchun Liu ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Double Stranded Dna

scholarly journals Strand displacement and duplex invasion into double-stranded DNA by pyrrolidinyl peptide nucleic acids

2015 ◽  
Vol 13 (35) ◽  
pp. 9223-9230 ◽  
Author(s):  
Peggy R. Bohländer ◽  
Tirayut Vilaivan ◽  
Hans-Achim Wagenknecht
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Dna Duplexes ◽  
Strand Displacement ◽  
Nucleic Acid Probes ◽  
Double Stranded Dna

Strand displacement and duplex invasion of DNA duplexes by pyrrolidinyl peptide nucleic acid are demonstrated using the concept of wavelength-shifting nucleic acid probes.

scholarly journals Recent Advances in Chemical Modification of Peptide Nucleic Acids

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Eriks Rozners
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Chemical Modifications ◽  
Practical Applications ◽  
High Affinity ◽  
Dna And Rna ◽  
Double Stranded Dna ◽  
Ongoing Effort

Peptide nucleic acid (PNA) has become an extremely powerful tool in chemistry and biology. Although PNA recognizes single-stranded nucleic acids with exceptionally high affinity and sequence selectivity, there is considerable ongoing effort to further improve properties of PNA for both fundamental science and practical applications. The present paper discusses selected recent studies that improve on cellular uptake and binding of PNA to double-stranded DNA and RNA. The focus is on chemical modifications of PNA's backbone and heterocyclic nucleobases. The paper selects representative recent studies and does not attempt to provide comprehensive coverage of the broad and vibrant field of PNA modification.

Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

2021 ◽  
Vol 23 (1) ◽  
pp. 219-228
Author(s):  
Nabanita Saikia ◽  
Mohamed Taha ◽  
Ravindra Pandey
Keyword(s):  
Nucleic Acid ◽  
Boron Nitride ◽  
Nucleic Acids ◽  
Dynamic Stability ◽  
Peptide Nucleic Acid ◽  
Rational Design ◽  
Peptide Nucleic Acids ◽  
Boron Nitride Nanotubes ◽  
Molecular Hybrids ◽  
Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

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