Enantioselective Borohydride Reduction of Ketones Catalyzed by Optically Active Cobalt(II) Complexes: Achievement of High Enantioselection by Modified Borohydrides with Furfuryl Alcohol Derivatives

1996 ◽  
Vol 25 (9) ◽  
pp. 737-738 ◽  
Author(s):  
Kiyoaki D. Sugi ◽  
Takushi Nagata ◽  
Tohru Yamada ◽  
Teruaki Mukaiyama
Keyword(s):  
Furfuryl Alcohol ◽  
Optically Active ◽  
Borohydride Reduction ◽  
Reduction Of Ketones

Enantioselective Borohydride Reduction Catalyzed by Optically Active β-Ketoiminato Cobalt Complexes

ChemInform ◽  
2004 ◽  
Vol 35 (1) ◽  
Author(s):  
Tohru Yamada ◽  
Takushi Nagata ◽  
Yuhki Ohtsuka ◽  
Taketo Ikeno ◽  
Teruaki Mukaiyama
Keyword(s):  
Cobalt Complexes ◽  
Optically Active ◽  
Borohydride Reduction

Use of enzymes as catalysts to promote key transformations in organic synthesis

1989 ◽  
Vol 324 (1224) ◽  
pp. 577-587 ◽  
Keyword(s):  
Organic Synthesis ◽  
Large Scale ◽  
Immobilized Enzymes ◽  
Building Blocks ◽  
Optically Active ◽  
The Past ◽  
Small Proteins ◽  
Areas Of Interest ◽  
Oxidation Of Benzene ◽  
Reduction Of Ketones

The field of biotransformations has developed rapidly over the past eight years. The use of esterases and lipases is now widespread; these enzymes are of particular importance in the production of optically active building blocks for organic synthesis as well as in large-scale processes involving the transesterification of fats. The latter area (i.e. the catalysis of esterification processes) has stimulated research into the properties of immobilized enzymes and the use of enzymes in low-water systems. In related work, enzymes have been used for the preparation of peptides and small proteins. Redox enzymes have been investigated extensively, particularly with regard to the stereocontrolled reduction of ketones to secondary alcohols. The methods for using commercially available enzymes of this type have become increasingly ‘userfriendly’. The controlled oxidation of hydrocarbon units is another area that has deserved increased attention. For example, oxidation of benzene and simple derivatives by Pseudomonas sp. has been researched by a number of U.K. groups. These recent advances in enzyme-catalysed reactions (using both whole-cell systems and partly purified protein) for the transformation of unnatural substrates is discussed and some areas of interest for the future are outlined.

ChemInform Abstract: Preparation of Optically Active 2-Cyclopenten-1,4-diol Derivatives from Furfuryl Alcohol.

ChemInform ◽  
2010 ◽  
Vol 28 (21) ◽  
pp. no-no
Author(s):  
T. T. CURRAN ◽  
D. A. HAY ◽  
C. P. KOEGEL ◽  
J. C. EVANS
Keyword(s):  
Furfuryl Alcohol ◽  
Optically Active
Sign in / Sign up

Export Citation Format

Share Document