New Addition Reactions of Cyclic Ethers with Esters and Thioesters Catalyzed by Quaternary Ammonium Salts or Crown Ether Complexes

1991 ◽  
Vol 20 (4) ◽  
pp. 697-700 ◽  
Author(s):  
Tadatomi Nishikubo ◽  
Kazuya Sato
Keyword(s):  
Crown Ether ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Cyclic Ethers ◽  
Addition Reactions ◽  
Crown Ether Complexes

Cinchona alkaloid-based chiral catalysts act as highly efficient multifunctional organocatalysts for the asymmetric conjugate addition of malonates to nitroolefins

2015 ◽  
Vol 13 (40) ◽  
pp. 10216-10225 ◽  
Author(s):  
Veeramanoharan Ashokkumar ◽  
Ayyanar Siva
Keyword(s):  
Michael Addition ◽  
Quaternary Ammonium ◽  
Conjugate Addition ◽  
Quaternary Ammonium Salts ◽  
Cinchona Alkaloid ◽  
Ammonium Salts ◽  
Addition Reactions ◽  
Chiral Catalysts ◽  
Reaction Conditions ◽  
Highly Efficient

New pentaerythritol tetrabromide based chiral quaternary ammonium salts have been prepared and used as organocatalysts for enantioselective Michael addition reactions between various nitroolefins and Michael donors under mild reaction conditions with very good chemical yields and ee's.

Highly enantioselective Michael addition reactions with new trimeric chiral phase transfer catalysts

2015 ◽  
Vol 39 (4) ◽  
pp. 3098-3104 ◽  
Author(s):  
Arockiam Jesin Beneto ◽  
Jayaraman Sivamani ◽  
Veeramanoharan Ashokkumar ◽  
Rajendiran Balasaravanan ◽  
Kumaraguru Duraimurugan ◽  
...  
Keyword(s):  
Michael Addition ◽  
Quaternary Ammonium ◽  
Phase Transfer ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Addition Reactions ◽  
Chiral Phase ◽  
Catalytic Activities ◽  
Phase Transfer Catalysts ◽  
Chiral Phase Transfer Catalysts

New types of mesitylene based tri-site containing asymmetric quaternary ammonium salts 9 (9a and 9b) were synthesized and their catalytic activities were studied using Michael addition reactions with various chalcones and diethylmalonate under mild basic conditions with very good yields and ee's.

Synthesis and stability of 1-aminoalkylphosphonic acid quaternary ammonium salts

2021 ◽  
Author(s):  
Tomasz K. Olszewski ◽  
Anna Brol
Keyword(s):  
Phosphonic Acid ◽  
Quaternary Ammonium ◽  
Alkylating Agent ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Aminoalkylphosphonic Acid

An effective protocol for quaternization of simple 1-aminoalkylphosphonic acids under basic conditions and using Me2SO4 as convenient alkylating agent is reported. In the course of reaction phosphonic acid quaternary ammonium...

scholarly journals Green Accelerated Synthesis, Antimicrobial Activity and Seed Germination Test of Quaternary Ammonium Salts of 1,2-bis(4-pyridyl)ethane

Molecules ◽  
2019 ◽  
Vol 24 (13) ◽  
pp. 2424 ◽  
Author(s):  
Tăbăcaru ◽  
Botezatu ◽  
Horincar ◽  
Furdui ◽  
Dinică
Keyword(s):  
Escherichia Coli ◽  
Triticum Aestivum ◽  
Seed Germination ◽  
Quaternary Ammonium ◽  
Pathogenic Bacteria ◽  
Classical Method ◽  
Triticum Aestivum L ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Radicle Growth

A family of fifteen quaternary ammonium salts (QAs), bearing the 1,2-bis(4-pyridyl)ethane core, were obtained using for the first time two different green methods, such as microwave (MW) and ultrasounds (US) irradiation, with very good yields and in much shorter times compared to the classical method, and an assay on their antimicrobial action against Escherichia coli (E. coli) was carried out. While 12 to 24 hours were required for complete alkylation of 1,2-bis(4-pyridyl)ethane by reactive halogenated derivatives in anhydrous solvent under reflux conditions, MW and US irradiation reduced the reaction time and the desired products were achieved in a few min. One of the aims of this study was to evaluate the antibacterial potential of the synthesized QAs against pathogenic bacteria, along with their impact on germination activity of wheat seeds (Triticum aestivum L.). The antibacterial activity of the QAs against Escherichia coli was explored by determining the minimum inhibitory concentration (MIC). The MIC values varied from 0.312 to 2.5 mg/mL, highlighting the lowest values attained for the derivatives containing methoxy, chlorine and benzofurane functional groups. The viability of aerobic bacteria was determined with the Tetrazolium/Formazan Test, a method that was found to be the best alternative approach with respect to the difuzimetric method. Seeds of Triticum aestivum L. were used for the evaluation of the germination indicators, such as seed germination (SG), the relative seed germination (RSG), the relative radicle growth (RRG), and the seed germination index (GI). The toxicity studies of QAs 1, 4 and 7, at two different concentrations, showed no inhibitory effect on seed germination.

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