HIGHLY STEREOSELECTIVE ALKYLATION REACTION OF ESTER ENOLATES GENERATED FROM δ-HYDROXY CARBOXYLIC ACID ESTERS

1986 ◽  
Vol 15 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Koichi Narasaka ◽  
Yutaka Ukaji
Keyword(s):  
Carboxylic Acid ◽  
Alkylation Reaction ◽  
Hydroxy Carboxylic Acid ◽  
Acid Esters

Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters

2019 ◽  
Author(s):  
Jiang Wang ◽  
Brian P. Cary ◽  
Peyton Beyer ◽  
Samuel H. Gellman ◽  
Daniel Weix
Keyword(s):  
Carboxylic Acid ◽  
Solid Support ◽  
Reaction Conditions ◽  
Decarboxylative Coupling ◽  
New Strategy ◽  
The Cross ◽  
Acyl Donors ◽  
Acid Esters

A new strategy for the synthesis of ketones is presented based upon the decarboxylative coupling of N-hydroxyphthalimide (NHP) esters with S-2-pyridyl thioesters. The reactions are selective for the cross-coupled product because NHP esters act as radical donors and the thioesters act as acyl donors. The reaction conditions are general and mild, with over 40 examples presented, including larger fragments and the 20-mer peptide Exendin(9-39) on solid support.

ChemInform Abstract: Practical Syntheses of Functionalized 1-Oxo-1,2,3,4-tetrahydro-β- carboline-3-carboxylic Acid Esters.

ChemInform ◽  
2010 ◽  
Vol 27 (33) ◽  
pp. no-no
Author(s):  
L. JEANNIN ◽  
J. SAPI ◽  
E. VASSILEVA ◽  
P. RENARD ◽  
J.-Y. LARONZE
Keyword(s):  
Carboxylic Acid ◽  
Acid Esters

Synthesis of Ethers by GaBr3-Catalyzed Reduction of Carboxylic Acid Esters and Lactones by Siloxanes

ChemSusChem ◽  
2013 ◽  
Vol 7 (2) ◽  
pp. 644-649 ◽  
Author(s):  
Ursula Biermann ◽  
Jürgen O. Metzger
Keyword(s):  
Carboxylic Acid ◽  
Acid Esters
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