A Novel Regioselective Desulfation Method Specific to Silyl Ester of Primary Sulfate Using Silylating Agents. Selective Preparation of Secondary Alkyl Sulfates Having a Primary Hydroxy Group

2001 ◽  
Vol 74 (1) ◽  
pp. 181-182 ◽  
Author(s):  
Mineko Horibe ◽  
Hiroyuki Oshita
Keyword(s):  
Hydroxy Group ◽  
Silyl Ester ◽  
Primary Hydroxy Group ◽  
Silylating Agents ◽  
Alkyl Sulfates

Direct Etherification of a Single Primary Hydroxy Group of β-Cyclodextrin

2021 ◽  
Vol 57 (1) ◽  
pp. 121-125
Author(s):  
N. V. Kutyasheva ◽  
G. I. Kurochkina ◽  
E. A. Solomatin ◽  
M. K. Grachev
Keyword(s):  
Hydroxy Group ◽  
Primary Hydroxy Group

scholarly journals Spin-labeling of Dexamethasone: Radical Stability vs. Temporal Resolution of EPR-Spectroscopy on Biological Samples

2018 ◽  
Vol 232 (5-6) ◽  
pp. 883-891 ◽  
Author(s):  
Karolina A. Walker ◽  
Michael L. Unbehauen ◽  
Silke B. Lohan ◽  
Siavash Saeidpour ◽  
Martina C. Meinke ◽  
...  
Keyword(s):  
Detection Limit ◽  
Hydroxy Group ◽  
Epr Spectroscopy ◽  
Biological Samples ◽  
Spin Labeling ◽  
Hacat Cells ◽  
Nmr Data ◽  
Primary Hydroxy Group ◽  
High Yields ◽  
Stability Measurements

AbstractSpin-labeling active compounds is a convenient way to prepare them for EPR spectroscopy with minimal alteration of the target molecule. In this study we present the labeling reaction of dexamethasone (Dx) with either TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxy) or PCA (3-(carboxy)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy) with high yields. According to NMR data, both labels are attached at the primary hydroxy group of the steroid. In subsequent spin-stability measurements both compounds were applied onto HaCaT cells. When the signal of Dx-TEMPO decreased below the detection limit within 3 h, the signal of Dx-PCA remained stable for the same period of time.

Preparation and Conformational Study of B-Ring Substituted Lupane Derivatives

2006 ◽  
Vol 71 (8) ◽  
pp. 1131-1160 ◽  
Author(s):  
Martin Dračínský ◽  
Simona Hybelbauerová ◽  
Jan Sejbal ◽  
Miloš Buděšínský
Keyword(s):  
Double Bond ◽  
Hydroxy Group ◽  
Molecular Modelling ◽  
Nmr Spectra ◽  
Hydroxy Derivative ◽  
Secondary Hydroxy Group ◽  
Conformational Study ◽  
Primary Hydroxy Group ◽  
Type 3 ◽  
C Nmr

New lupane-type triterpenoids with 5(6) double bond were prepared using the method of partial demethylation on carbon C-4. Hydroboration of the double bond led to 6α-hydroxy derivative. By the oxidation and following reduction of 6α-hydroxy derivative the 6-oxo and 6β-hydroxy derivatives were prepared. A new method for selective oxidation of secondary hydroxy group in the presence of primary hydroxy group was performed. The conformation of ring A of new lupane-type 3-oxo derivatives with a substituent on ring B was elucidated on the bases of 1H and 13C NMR spectra and molecular modelling.

Simple and practical method for selective acylation of primary hydroxy group catalyzed by N-methyl-2-phenylimidazole (Ph-NMI) or 2-phenylimidazo[2,1-b]benzothiazoles (Ph-IBT)

2014 ◽  
Vol 55 (51) ◽  
pp. 7039-7042 ◽  
Author(s):  
Kouta Ibe ◽  
Yu-suke Hasegawa ◽  
Misuzu Shibuno ◽  
Tsukasa Shishido ◽  
Yuzo Sakai ◽  
...  
Keyword(s):  
Hydroxy Group ◽  
Practical Method ◽  
Primary Hydroxy Group ◽  
Selective Acylation
Sign in / Sign up

Export Citation Format

Share Document