Preparation and Characterization of Inclusion Complexes of Poly(alkyl vinyl ether) with Cyclodextrins

1998 ◽  
Vol 71 (3) ◽  
pp. 535-542 ◽  
Author(s):  
Akira Harada ◽  
Miyuko Okada ◽  
Mikiharu Kamachi
1992 ◽  
Vol 54-55 (1) ◽  
pp. 95-106 ◽  
Author(s):  
A. Verma ◽  
M. Glagola ◽  
A. Prasad ◽  
H. Marand ◽  
J. S. Riffle

Author(s):  
D. Nagasamy Venkatesh ◽  
S. Karthick ◽  
M. Umesh ◽  
G. Vivek ◽  
R.M. Valliappan ◽  
...  

Roxythromycin/ β-cyclodextrin (Roxy/ β-CD) dispersions were prepared with a view to study the influence of β-CD on the solubility and dissolution rate of this poorly soluble drug. Phase-solubility profile indicated that the solubility of roxythromycin was significantly increased in the presence of β-cyclodextrin and was classified as AL-type, indicating the 1:1 stoichiometric inclusion complexes. Physical characterization of the prepared systems was carried out by differential scanning calorimetry (DSC), X-ray diffraction studies (XRD) and IR studies. Solid state characterization of the drug β-CD binary system using XRD, FTIR and DSC revealed distinct loss of drug crystallinity in the formulation, ostensibly accounting for enhancement of dissolution rate.


Author(s):  
Alexander Puentes Parra ◽  
Jorge Ariel Martínez Ramírez ◽  
Claudia Elizabeth Mora Huertas

Polymer ◽  
2001 ◽  
Vol 42 (16) ◽  
pp. 6907-6912 ◽  
Author(s):  
Francis E Porbeni ◽  
Efe M Edeki ◽  
I Dan Shin ◽  
Alan E Tonelli
Keyword(s):  

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