scholarly journals Optical Resolution oferythro-2-Amino-1,2-diphenylethanol by Reciprocal Crystallization of the Diastereomeric Salts with (−)-Mandelic Acid on Alternate Seeding

1986 ◽  
Vol 59 (9) ◽  
pp. 2915-2916 ◽  
Author(s):  
Kazuhiko Saigo ◽  
Izuru Sugiura ◽  
Ikuko Shida ◽  
Kouzou Tachibana ◽  
Masaki Hasegawa
Keyword(s):  
Mandelic Acid ◽  
Optical Resolution ◽  
Diastereomeric Salts

scholarly journals Microwave-Assisted Synthesis of(±)-Mandelic Acid-d5, Optical Resolution, and Absolute Configuration Determination

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Claudio Bruno ◽  
Giovanni Lentini ◽  
Angelo Lovece ◽  
Maria Maddalena Cavalluzzi ◽  
Alessia Carocci ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Mandelic Acid ◽  
Optical Resolution ◽  
Racemic Mixture ◽  
Microwave Assisted Synthesis ◽  
Salt Formation ◽  
Microwave Assisted ◽  
Diastereomeric Salts ◽  
Chiral Capillary Electrophoresis ◽  
Resolving Agents

An efficient microwave-assisted synthesis of(±)-mandelic acid-d5was developed. The racemic mixture was resolved by diastereomeric salt formation using 1-phenylethylamine enantiomers as resolving agents. At each step, the resolution process was checked by determining mandelic acid-d5enantiomer ee values directly on fractional crystallized diastereomeric salts by chiral capillary electrophoresis analysis. Highly enriched (−)- and (+)-mandelic acid-d5(95% and 90% ee, resp.) were obtained and their absolute configurations—RandS, respectively—were determined by correlation of the (−)-mandelic acid-d5circular dichroism spectrum to the (R)-mandelic acid one.

Optical resolution of N-formylphenylalanine succeeds by crystal growth rate differences of diastereomeric salts

2007 ◽  
Vol 18 (2) ◽  
pp. 260-264 ◽  
Author(s):  
Laura Bereczki ◽  
Emese Pálovics ◽  
Petra Bombicz ◽  
György Pokol ◽  
Elemér Fogassy ◽  
...  
Keyword(s):  
Growth Rate ◽  
Crystal Growth ◽  
Optical Resolution ◽  
Crystal Growth Rate ◽  
Diastereomeric Salts

Optical Resolution of Mandelic Acid by Complexation with (S)-(+)-Alanine.

ChemInform ◽  
2003 ◽  
Vol 34 (5) ◽  
Author(s):  
Koichi Tanaka ◽  
Takatumi Fukuoka ◽  
Matoo Shiro
Keyword(s):  
Mandelic Acid ◽  
Optical Resolution

Optical Resolution of Phenylalanine and Mandelic Acid by Complex Formation with Copper(II) Ion

1992 ◽  
Vol 65 (11) ◽  
pp. 3149-3152 ◽  
Author(s):  
Yasushi Yamamoto ◽  
Shinji Kato ◽  
Hiroshi Yamashita ◽  
Takashi Maekawa
Keyword(s):  
Complex Formation ◽  
Mandelic Acid ◽  
Optical Resolution
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