scholarly journals Studies on Hydroxy Amino Acids. I. A New Synthesis of Aziridine Derivative from β-Hydroxy α-Amino Acid

1968 ◽  
Vol 41 (6) ◽  
pp. 1353-1355 ◽  
Author(s):  
Kenji Okawa ◽  
Teiji Kinutani ◽  
Katsunobu Sakai
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Hydroxy Amino ◽  
New Synthesis

scholarly journals Amino acid distributions around O-linked glycosylation sites

1991 ◽  
Vol 275 (2) ◽  
pp. 529-534 ◽  
Author(s):  
I B Wilson ◽  
Y Gavel ◽  
G von Heijne
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Sequence Data ◽  
Prominent Feature ◽  
Primary Sequence ◽  
Hydroxy Amino ◽  
Glycosylation Sites ◽  
Sequence Requirements ◽  
Primary Sequence Data ◽  
Glycosylated Proteins

To study the sequence requirements for addition of O-linked N-acetylgalactosamine to proteins, amino acid distributions around 174 O-glycosylation sites were compared with distributions around non-glycosylated sites. In comparison with non-glycosylated serine and threonine residues, the most prominent feature in the vicinity of O-glycosylated sites is a significantly increased frequency of proline residues, especially at positions -1 and +3 relative to the glycosylated residues. Alanine, serine and threonine are also significantly increased. The high serine and threonine content of O-glycosylated regions is due to the presence of clusters of several closely spaced glycosylated hydroxy amino acids in many O-glycosylated proteins. Such clusters can be predicted from the primary sequence in some cases, but there is no apparent possibility of predicting isolated O-glycosylation sites from primary sequence data.

scholarly journals Studies on Hydroxy Amino Acids. IV. Syntheses of Several Peptides Containing Aziridinecarboxylic Acid Derived from the Corresponding Hydroxy Amino Acid Derivatives

1972 ◽  
Vol 45 (4) ◽  
pp. 1162-1167 ◽  
Author(s):  
Yasuo Nakagawa ◽  
Takashi Tsuno ◽  
Kiichiro Nakajima ◽  
Michio Iwai ◽  
Haruki Kawai ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Hydroxy Amino Acid ◽  
Hydroxy Amino
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