scholarly journals Ion-pair Formation of Some Substitution-inert Complexes and Sulfate Ions. Determination of Association Constants Using Polarographic Diffusion Current

1966 ◽  
Vol 39 (2) ◽  
pp. 366-369 ◽  
Author(s):  
Nobuyuki Tanaka ◽  
Kazuko Ogino (née Ebata) ◽  
Gen Sato
Keyword(s):  
Ion Pair ◽  
Pair Formation ◽  
Association Constants ◽  
Diffusion Current ◽  
Sulfate Ions ◽  
Ion Pair Formation

Rapid Colorimetric Assay of Trimethoprim and Sulfamethoxazole in Pharmaceuticals

1983 ◽  
Vol 66 (6) ◽  
pp. 1447-1449 ◽  
Author(s):  
Asis K Sanyal ◽  
Dinabandhu Laha
Keyword(s):  
Solvent Extraction ◽  
Colorimetric Assay ◽  
Pharmaceutical Preparations ◽  
Ion Pair ◽  
Pair Formation ◽  
Bromophenol Blue ◽  
Colorimetric Determination ◽  
Ion Pair Formation ◽  
Subsequent Measurement

Abstract A method is described for the direct colorimetric determination of trimethoprim and sulfamethoxazole in pharmaceutical preparations, without prior separation. Estimation of trimethoprim is based on its ion-pair formation with bromophenol blue and subsequent measurement of absorbance of the ionpair at 418 nm. Estimation of sulfamethoxazole is possible without removal of trimethoprim by solvent extraction.

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