Convergent Synthesis of the WXYZA’B’C’D’E’F’ Ring Segment of Maitotoxin

2022 ◽  
Author(s):  
Keitaro Umeno ◽  
Hisaaki Onoue ◽  
Keiichi Konoki ◽  
Kohei Torikai ◽  
Yoko Yasuno ◽  
...  
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment

Convergent Synthesis of the A—F Ring Segment of Yessotoxin and Adriatoxin.

ChemInform ◽  
2004 ◽  
Vol 35 (10) ◽  
Author(s):  
Isao Kadota ◽  
Hirokazu Ueno ◽  
Yoshinori Yamamoto
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment ◽  
F Ring

Convergent synthesis of the A–F ring segment of yessotoxin and adriatoxin

2003 ◽  
Vol 44 (50) ◽  
pp. 8935-8938 ◽  
Author(s):  
Isao Kadota ◽  
Hirokazu Ueno ◽  
Yoshinori Yamamoto
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment ◽  
F Ring

Convergent synthesis of the F–K ring segment of brevetoxin B

2003 ◽  
Vol 44 (43) ◽  
pp. 7929-7932 ◽  
Author(s):  
Isao Kadota ◽  
Naoko Nishina ◽  
Hiroki Nishii ◽  
Shigetoshi Kikuchi ◽  
Yoshinori Yamamoto
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment

Convergent Synthesis of the FGHI Ring Segment (I) of Yessotoxin.

ChemInform ◽  
2006 ◽  
Vol 37 (18) ◽  
Author(s):  
Isao Kadota ◽  
Hirokazu Ueno ◽  
Yuki Sato ◽  
Yoshinori Yamamoto
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment

Convergent synthesis of the A–E ring segment of ciguatoxin CTX3C

Tetrahedron ◽  
2009 ◽  
Vol 65 (37) ◽  
pp. 7784-7789 ◽  
Author(s):  
Isao Kadota ◽  
Takashi Abe ◽  
Miyuki Uni ◽  
Hiroyoshi Takamura ◽  
Yoshinori Yamamoto
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment

Convergent synthesis of the FGHI ring segment of yessotoxin

2006 ◽  
Vol 47 (1) ◽  
pp. 89-92 ◽  
Author(s):  
Isao Kadota ◽  
Hirokazu Ueno ◽  
Yuki Sato ◽  
Yoshinori Yamamoto
Keyword(s):  
Convergent Synthesis ◽  
Ring Segment

A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals

Tetrahedron ◽  
2002 ◽  
Vol 58 (9) ◽  
pp. 1697-1708 ◽  
Author(s):  
Yan Xing Jia ◽  
Xin Li ◽  
Bin Wu ◽  
Xue Zhi Zhao ◽  
Yong Qiang Tu
Keyword(s):  
Protease Inhibitors ◽  
Convergent Synthesis ◽  
Hiv 1

Convergent Synthesis of Immune Inhibitor IMMH002

Synthesis ◽  
2020 ◽  
Author(s):  
Qiong Xiao ◽  
Si Chen ◽  
Zeyu Shi ◽  
Dali Yin
Keyword(s):  
Environmental Impact ◽  
Lewis Acid ◽  
Column Chromatography ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Convergent Synthesis ◽  
Quality Problem ◽  
Cross Coupling Reaction

AbstractA convergent synthesis of IMMH002 in 36% overall yield starting from bromobenzene is described with a key Suzuki–Miyaura cross-coupling reaction used to provide a crucial intermediate. The route does not require column chromatography and solves the most intractable quality problem caused by a homologue by-product in the original linear synthesis. Furthermore, reducing the use of Lewis acid mediated reactions improves the environmental impact of the synthesis and reduces overall waste. The new route described herein is more efficient, convenient, reliable, and economically more viable when compared to the previously reported linear route.

Reducing-Agent-Free Convergent Synthesis of Hydroxyimino-Decorated Tetracyclic Fused Cinnolines via RhIII-Catalyzed Annulation Using Nitroolefins

2021 ◽  
Vol 86 (3) ◽  
pp. 2734-2747
Author(s):  
Pidiyara Karishma ◽  
Chikkagundagal K. Mahesha ◽  
Sanjay K. Mandal ◽  
Rajeev Sakhuja
Keyword(s):  
Reducing Agent ◽  
Convergent Synthesis
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