Systematic reconstruction of the cellular trajectories of mammalian embryogenesis

2021 ◽  
Author(s):  
Bobby Ranjan
Keyword(s):  
Mammalian Embryogenesis

scholarly journals Methylation and imprinting in mammalian embryogenesis

1995 ◽  
Vol 11 (5) ◽  
pp. 5-14
Author(s):  
L. M. Morozova
Keyword(s):  
Mammalian Embryogenesis

scholarly journals Medawar’s PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation

2021 ◽  
Vol 12 ◽  
Author(s):  
Ellen Menkhorst ◽  
Nandor Gabor Than ◽  
Udo Jeschke ◽  
Gabriela Barrientos ◽  
Laszlo Szereday ◽  
...  
Keyword(s):  
Immune Cell ◽  
Successful Pregnancy ◽  
Fetal Health ◽  
The Past ◽  
Mammalian Embryogenesis ◽  
Carbohydrate Ligands ◽  
Membrane Bound

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many processes required for a successful pregnancy. Over the past decades, increasing evidence gathered from in vitro and in vivo experiments indicate that members of the galectin family specifically bind to both intracellular and membrane bound carbohydrate ligands regulating angiogenesis, immune-cell adaptations required to tolerate the fetal semi-allograft and mammalian embryogenesis. Therefore, galectins play important roles in fetal development and placentation contributing to maternal and fetal health. This review discusses the expression and role of galectins during the course of pregnancy, with an emphasis on maternal immune adaptions and galectin-glycan interactions uncovered in the recent years. In addition, we summarize the galectin fingerprints associated with pathological gestation with particular focus on preeclampsia.

Mesoderm-inducing properties of INT-2 and kFGF: two oncogene-encoded growth factors related to FGF

Development ◽  
1989 ◽  
Vol 106 (1) ◽  
pp. 79-83 ◽  
Author(s):  
G.D. Paterno ◽  
L.L. Gillespie ◽  
M.S. Dixon ◽  
J.M. Slack ◽  
J.K. Heath
Keyword(s):  
Growth Factors ◽  
Embryonic Development ◽  
Xenopus Laevis ◽  
Dna Synthesis ◽  
Signalling Pathways ◽  
Control Mechanisms ◽  
Animal Pole ◽  
Receptor Signalling ◽  
Mammalian Embryogenesis ◽  
Mesoderm Formation

Many theories of neoplasia suggest that oncogenic transformations result from aberrations in the control mechanisms which normally regulate growth and differentiation during embryonic development. It has recently become clear that many proto-oncogenes are differentially expressed during embryonic development and may thus be important embryonic regulatory molecules. We report here that the products of two transforming oncogenes int-2 and hst/ks (now called kfgf) can, with different potencies, induce mesoderm formation in isolated Xenopus laevis animal pole explants and stimulate DNA synthesis in mammalian fibroblasts. The results suggest that these proteins may function as mesoderm inducers in mammalian embryogenesis and that similar receptor/signalling pathways may be utilized for developmental and oncogenic processes. Finally, we have shown that the Xenopus assay system used in this study provides a powerful screen for protein factors that are active in development.

scholarly journals mtDNA Chromatin-like Organization Is Gradually Established during Mammalian Embryogenesis

iScience ◽  
2019 ◽  
Vol 12 ◽  
pp. 141-151 ◽  
Author(s):  
Shani Marom ◽  
Amit Blumberg ◽  
Anshul Kundaje ◽  
Dan Mishmar
Keyword(s):  
Mammalian Embryogenesis

Transforming growth factor betas in mammalian embryogenesis

1990 ◽  
Vol 2 (3) ◽  
pp. 153-168 ◽  
Author(s):  
Rosemary J. Akhurst ◽  
David R. FitzPatrick ◽  
Derek Gatherer ◽  
Sigrd A. Lehnert ◽  
Fergus A. Millan
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Mammalian Embryogenesis

Membrane dynamics in mammalian embryogenesis: Implication in signal regulation

2016 ◽  
Vol 108 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Yoh Wada ◽  
Ge-Hong Sun-Wada ◽  
Nobuyuki Kawamura ◽  
Jyunichiro Yasukawa
Keyword(s):  
Membrane Dynamics ◽  
Mammalian Embryogenesis ◽  
Signal Regulation

scholarly journals In vitro modeling of early mammalian embryogenesis

2020 ◽  
Vol 13 ◽  
pp. 134-143 ◽  
Author(s):  
Anna-Katerina Hadjantonakis ◽  
Eric D. Siggia ◽  
Mijo Simunovic
Keyword(s):  
In Vitro Modeling ◽  
Mammalian Embryogenesis

scholarly journals Adrenomedullin in mammalian embryogenesis

2002 ◽  
Vol 57 (1) ◽  
pp. 40-54 ◽  
Author(s):  
Mercedes Garayoa ◽  
Elena Bodegas ◽  
Frank Cuttitta ◽  
Luis M. Montuenga
Keyword(s):  
Mammalian Embryogenesis
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