scholarly journals Social stress increases plasma cortisol and reduces forebrain cell proliferation in subordinate male zebrafish (Danio rerio)

2018 ◽  
Vol 222 (2) ◽  
pp. jeb194894 ◽  
Author(s):  
Jonathan Tea ◽  
Sarah L. Alderman ◽  
Kathleen M. Gilmour
Keyword(s):  
Cell Proliferation ◽  
Danio Rerio ◽  
Social Stress ◽  
Plasma Cortisol ◽  
Subordinate Male

P2 OPPOSITE AUTONOMIC AND NEUROENDOCRINE ALTERATIONS IN DOMINANT AND SUBORDINATE MALE MICE UNDER CHRONIC SOCIAL STRESS

2004 ◽  
Vol 15 (5) ◽  
pp. A8
Author(s):  
A. Bartolomucci ◽  
F. D??Amato ◽  
R. Rizzi ◽  
L. Garbugino ◽  
R. Conti ◽  
...  
Keyword(s):  
Social Stress ◽  
Male Mice ◽  
Chronic Social Stress ◽  
Subordinate Male

scholarly journals The effect of social stress on adrenal axis activity in horses: the importance of monitoring corticosteroid-binding globulin capacity

1998 ◽  
Vol 157 (3) ◽  
pp. 425-432 ◽  
Author(s):  
SL Alexander ◽  
CH Irvine
Keyword(s):  
Social Stress ◽  
Plasma Cortisol ◽  
Binding Capacity ◽  
Plasma Concentrations ◽  
Social Instability ◽  
Total Cortisol ◽  
Adrenal Axis ◽  
Free Cortisol ◽  
Corticosteroid Binding Globulin ◽  
Cortisol Levels

Plasma cortisol is largely bound to corticosteroid-binding globulin (CBG), which regulates its bioavailability by restricting exit from capillaries. Levels of CBG may be altered by several factors including stress and this can influence the amount of cortisol reaching cells. This study investigated the effect of social instability on plasma concentrations of CBG, total and free (not protein bound) cortisol in horses. Horses new to our research herd ('newcomers') were confined in a small yard with four dominant resident horses for 3-4 h daily for 3-4 (n = 5) or 9-14 (n = 3) days. Jugular blood was collected in the mornings from newcomers before the period of stress began ('pre-stress'), and then before each day's stress. Residents were bled before stress on the first and thirteenth day. Residents always behaved aggressively towards newcomers. By the end of the stress period, all newcomers were subordinate to residents. In newcomers (n = 8) after 3-4 days of social stress, CBG binding capacity had fallen (P = 0.0025), while free cortisol concentrations had risen (P = 0.0016) from pre-stress values. In contrast, total cortisol did not change. In residents, CBG had decreased slightly but significantly (P = 0.0162) after 12 days of stress. Residents and newcomers did not differ in pre-stress CBG binding capacity, total or free cortisol concentrations. However, by the second week of stress, CBG binding capacity was lower (P = 0.015) and free cortisol higher (P = 0.030) in newcomers (n = 3) than in residents. Total cortisol did not differ between the groups. In conclusion social stress clearly affected the adrenal axis of subordinate newcomer horses, lowering the binding capacity of CBG and raising free cortisol concentrations. However, no effect of stress could be detected when only total cortisol was measured. Therefore, to assess adrenal axis status accurately in horses, it is essential to monitor the binding capacity of CBG and free cortisol concentrations in addition to total cortisol levels.

Surplus dietary tryptophan reduces plasma cortisol and noradrenaline concentrations and enhances recovery after social stress in pigs

2005 ◽  
Vol 85 (4) ◽  
pp. 469-478 ◽  
Author(s):  
S KOOPMANS ◽  
M RUIS ◽  
R DEKKER ◽  
H VANDIEPEN ◽  
M KORTE ◽  
...  
Keyword(s):  
Social Stress ◽  
Plasma Cortisol

Social stress-related behavior affects hippocampal cell proliferation in mice

2006 ◽  
Vol 89 (2) ◽  
pp. 123-127 ◽  
Author(s):  
Rupshi Mitra ◽  
Karan Sundlass ◽  
Karen J. Parker ◽  
Alan F. Schatzberg ◽  
David M. Lyons
Keyword(s):  
Cell Proliferation ◽  
Social Stress ◽  
Hippocampal Cell

Forebrain cell proliferation, behavior, and physiology of zebrafish, Danio rerio, kept in enriched or barren environments

2010 ◽  
Vol 101 (1) ◽  
pp. 32-39 ◽  
Author(s):  
Kristine von Krogh ◽  
Christina Sørensen ◽  
Göran E. Nilsson ◽  
Øyvind Øverli
Keyword(s):  
Cell Proliferation ◽  
Danio Rerio

scholarly journals Expression of ion transport genes in ionocytes isolated from larval zebrafish (Danio rerio) exposed to acidic or Na+-deficient water

2020 ◽  
Vol 319 (4) ◽  
pp. R412-R427
Author(s):  
K. Shir-Mohammadi ◽  
S. F. Perry
Keyword(s):  
Gene Expression ◽  
Cell Proliferation ◽  
Ion Transport ◽  
Danio Rerio ◽  
Ionic Composition ◽  
Low Ph ◽  
Activity Level ◽  
Whole Body ◽  
Mrna Levels ◽  
Acid Base

In zebrafish ( Danio rerio), a specific ionocyte subtype, the H+-ATPase-rich (HR) cell, is presumed to be a significant site of transepithelial Na+ uptake/acid secretion. During acclimation to environments differing in ionic composition or pH, ionic and acid–base regulations are achieved by adjustments to the activity level of HR cell ion transport proteins. In previous studies, the quantitative assessment of mRNA levels for genes involved in ionic and acid–base regulations relied on measurements using homogenates derived from the whole body (larvae) or the gill (adult). Such studies cannot distinguish whether any differences in gene expression arise from adjustments of ionocyte subtype numbers or transcriptional regulation specifically within individual ionocytes. The goal of the present study was to use fluorescence-activated cell sorting to separate the HR cells from other cellular subpopulations to facilitate the measurement of gene expression of HR cell-specific transporters and enzymes from larvae exposed to low pH (pH 4.0) or low Na+ (5 μM) conditions. The data demonstrate that treatment of larvae with acidic water for 4 days postfertilization caused cell-specific increases in H+-ATPase ( atp6v1aa), ca17a, ca15a, nhe3b, and rhcgb mRNA in addition to increases in mRNA linked to cell proliferation. In fish exposed to low Na+, expression of nhe3b and rhcgb was increased owing to HR cell-specific regulation and elevated numbers of HR cells. Thus, the results of this study demonstrate that acclimation to low pH or low Na+ environmental conditions is facilitated by HR cell-specific transcriptional control and by HR cell proliferation.

scholarly journals Modulation of cell proliferation in the embryonic retina of zebrafish (Danio rerio)

2000 ◽  
Vol 219 (3) ◽  
pp. 391-401 ◽  
Author(s):  
Zheng Li ◽  
Minjie Hu ◽  
Malgorzata J. Ochocinska ◽  
Nancy M. Joseph ◽  
Stephen S. Easter
Keyword(s):  
Cell Proliferation ◽  
Danio Rerio ◽  
Embryonic Retina

scholarly journals Class II biocompatible E-Shell 300 3D printing material causes severe developmental toxicity in Danio rerio embryos and reduced cell proliferation in vitro – implications for 3D printed microfluidics

RSC Advances ◽  
2021 ◽  
Vol 11 (27) ◽  
pp. 16252-16267
Author(s):  
Zuzana Nejedlá ◽  
David Poustka ◽  
Regina Herma ◽  
Michaela Liegertová ◽  
Marcel Štofik ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
3D Printing ◽  
Danio Rerio ◽  
Negative Impact ◽  
Developmental Toxicity ◽  
Post Treatment ◽  
3D Printed ◽  
Proliferation In Vitro ◽  
Danio Rerio Embryos

E-Shell 300 3D-printed material demonstrated a considerable negative impact on cell proliferation and severe developmental toxicity due to release of surfactant residues. Post-treatment with ethanol improved the biocompatibility of the material.

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