scholarly journals Glucose metabolism ontogenesis in rainbow trout (Oncorhynchus mykiss) in the light of the recently sequenced genome: new tools for intermediary metabolism programming

2016 ◽  
Vol 219 (5) ◽  
pp. 734-743 ◽  
Author(s):  
Lucie Marandel ◽  
Vincent Véron ◽  
Anne Surget ◽  
Élisabeth Plagnes-Juan ◽  
Stéphane Panserat
Keyword(s):  
Rainbow Trout ◽  
Glucose Metabolism ◽  
Oncorhynchus Mykiss ◽  
Intermediary Metabolism ◽  
Rainbow Trout Oncorhynchus Mykiss

The Influence of Social Status on Hepatic Glucose Metabolism in Rainbow Trout Oncorhynchus mykiss

2012 ◽  
Vol 85 (4) ◽  
pp. 309-320 ◽  
Author(s):  
Kathleen M. Gilmour ◽  
Sheryn Kirkpatrick ◽  
Andrey Massarsky ◽  
Brenda Pearce ◽  
Sarah Saliba ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Glucose Metabolism ◽  
Oncorhynchus Mykiss ◽  
Social Status ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Hepatic Glucose Metabolism ◽  
Hepatic Glucose

Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture

2010 ◽  
Vol 299 (2) ◽  
pp. R562-R572 ◽  
Author(s):  
Joan Sánchez-Gurmaches ◽  
Lourdes Cruz-Garcia ◽  
Joaquím Gutiérrez ◽  
Isabel Navarro
Keyword(s):  
Oleic Acid ◽  
Rainbow Trout ◽  
Glucose Metabolism ◽  
Oncorhynchus Mykiss ◽  
Acid Metabolism ◽  
Peroxisome Proliferator ◽  
Endocrine Control ◽  
Peroxisome Proliferator Activated Receptor ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Igf I

The effects of insulin and IGF-I on fatty acid (FA) and glucose metabolism were examined using oleic acid or glucose as tracers in differentiated rainbow trout ( Oncorhynchus mykiss ) myotubes. Insulin and IGF-I significantly reduced the production of CO2 from oleic acid with respect to the control values. IGF-I also significantly reduced the production of acid-soluble products (ASP) and the concentration of FA in the medium, while cellular triacylglycerols (TAG) tended to increase. Only insulin produced a significant accumulation of glycogen inside the cells in glucose distribution experiments. Incubation with catecholamines did not affect oleic acid metabolism. Cells treated with rapamycin [a target of rapamycin (TOR) inhibitor] significantly increased the oxidation of oleic acid to CO2 and ASP, while the accumulation of TAG diminished. Rosiglitazone (a peroxisome proliferator-activated receptor γ agonist) and etomoxir (a CPT-1 inhibitor) produced a severe and significant reduction in the production of CO2 and ASP. Rosiglitazone and etomoxir also produced a significant accumulation of FA outside and inside the cells, respectively. No significant effects of these drugs on glucose distribution were observed. These data indicate that insulin and IGF-I act as anabolic hormones in trout myotubes in both oleic acid and glucose metabolism, although glucose oxidation appears to be less sensitive than FA oxidation to insulin and IGF-I. The use of rapamycin, etomoxir, and rosiglitazone may help us to understand the mechanisms of regulation of lipid metabolism in fish.

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