scholarly journals Cold-acclimation-induced non-shivering thermogenesis in birds is associated with upregulation of avian UCP but not with innate uncoupling or altered ATP efficiency

2010 ◽  
Vol 213 (14) ◽  
pp. 2476-2482 ◽  
Author(s):  
L. Teulier ◽  
J.-L. Rouanet ◽  
D. Letexier ◽  
C. Romestaing ◽  
M. Belouze ◽  
...  
Keyword(s):  
Cold Acclimation ◽  
Avian Ucp ◽  
Shivering Thermogenesis

CHANGES IN THE RESTING POTENTIAL OF SKELETAL MUSCLE IN RATS WITH COLD ACCLIMATION

1966 ◽  
Vol 44 (5) ◽  
pp. 791-802 ◽  
Author(s):  
M. H. Sherebrin ◽  
A. C. Burton
Keyword(s):  
Skeletal Muscle ◽  
Electrical Properties ◽  
Cold Acclimation ◽  
White Muscle ◽  
Single Cells ◽  
Temperature Gradients ◽  
Resting Potential ◽  
The Mean ◽  
Shivering Thermogenesis ◽  
Main Factor

The resting potential of single cells in the flexor thigh muscles of rats was measured in an attempt to find a change in the electrical properties of the cell membrane with cold acclimation, in order to identify and relate metabolic changes occurring with non-shivering thermogenesis. The mean resting potential of cells in cold-acclimated rats was found to be slightly but significantly higher than in the controls. A larger temperature gradient with depth was measured in the cold-acclimated animals than in the controls. If the Q10 of resting potential with temperature is as great as 1.16, the higher potential in the cold-acclimated rats may be accounted for by this temperature difference. The resting potential was also found to vary with depth in both groups of rats. This could not be attributed to temperature gradients, and change from red to white muscle cells with depth is thought to be the main factor for the increase of potential with depth.

An uncoupling protein homologue putatively involved in facultative muscle thermogenesis in birds

2001 ◽  
Vol 353 (3) ◽  
pp. 441-444 ◽  
Author(s):  
Serge RAIMBAULT ◽  
Sami DRIDI ◽  
Frédérique DENJEAN ◽  
Joël LACHUER ◽  
Elodie COUPLAN ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Uncoupling Protein ◽  
Chicken Line ◽  
Diet Induced Thermogenesis ◽  
Avian Ucp ◽  
Developing Muscle ◽  
Chicken Skeletal Muscle ◽  
Shivering Thermogenesis

The cDNA of an uncoupling protein (UCP) homologue was obtained by screening a chicken skeletal-muscle library. The predicted 307-amino-acid sequence of avian UCP (avUCP) is 55, 70, 70 and 46% identical with mammalian UCP1, UCP2 and UCP3 and plant UCP respectively. avUCP mRNA expression is restricted to skeletal muscle and its abundance was increased 1.3-fold in a chicken line showing diet-induced thermogenesis, and 3.6- and 2.6-fold in cold-acclimated and glucagon-treated ducklings developing muscle non-shivering thermogenesis respectively. The present data support the implication of avUCP in avian energy expenditure.

Stimulatory effects of cold exposure and cold acclimation on glucose uptake in rat peripheral tissues

1990 ◽  
Vol 259 (5) ◽  
pp. R1043-R1049 ◽  
Author(s):  
A. L. Vallerand ◽  
F. Perusse ◽  
L. J. Bukowiecki
Keyword(s):  
Adipose Tissue ◽  
Glucose Uptake ◽  
Cold Acclimation ◽  
Cold Exposure ◽  
Skeletal Muscles ◽  
Contractile Activity ◽  
Peripheral Tissues ◽  
Brown Adipose ◽  
Shivering Thermogenesis ◽  
Stimulation Of

The effects of cold exposure on the net rates of 2-[3H]deoxy-D-glucose uptake (Ki) in rat peripheral tissues were investigated comparatively in warm- and cold-acclimated animals to determine whether cold acclimation induces regulatory alterations in glucose metabolism. Acute exposure of warm-acclimated (25 degrees C) rats to cold (48 h at 5 degrees C) markedly increased the Ki values in red and white skeletal muscles (2-5 times), in the heart (8 times), in several white adipose tissue (WAT) depots (4-20 times), and in brown adipose tissue (BAT) (110 times). After cold acclimation (3 wk at 5 degrees C), the Ki values further increased in the heart (15 times) and WAT (up to 29 times) but decreased in BAT (36 times). Remarkably, glucose uptake was still increased in muscles of cold-exposed/cold-acclimated animals (that do not shiver), demonstrating that enhanced glucose uptake may occur in muscles in the absence of shivering thermogenesis (or contractile activity). When cold-acclimated rats were returned to the warm for 18 h, the Ki values of all tissues, except WAT, returned to control levels. Cold exposure synergistically potentiated the stimulation of tissue glucose uptake induced by a maximal effective dose of insulin (0.5 U/kg iv) in warm- as well as in cold-acclimated animals.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Changes in mitochondrial components of hamster brown adipose tissue in response to cold acclimation

1981 ◽  
Vol 194 (2) ◽  
pp. 653-656 ◽  
Author(s):  
M E Yacoe
Keyword(s):  
Adipose Tissue ◽  
Atpase Activity ◽  
Brown Adipose Tissue ◽  
Cold Acclimation ◽  
Liver Mitochondria ◽  
Adaptive Change ◽  
Brown Adipose ◽  
Shivering Thermogenesis ◽  
Respiration Characteristic

Cold acclimation of hamsters was found to result in an increase in cytochrome concentration relative to ATPase activity in brown adipose tissue mitochondria, but not in liver mitochondria. These data lend support to the hypothesis that the uncoupled respiration characteristic of non-shivering thermogenesis is the result of an adaptive change in the composition of brown adipose tissue mitochondria in response to cold acclimation.

Increase in cytochrome oxidase capacity of BAT and other tissues in cold-acclimated gerbils

1990 ◽  
Vol 258 (5) ◽  
pp. R1291-R1298 ◽  
Author(s):  
M. Bourhim ◽  
H. Barre ◽  
S. Oufara ◽  
Y. Minaire ◽  
J. Chatonnet ◽  
...  
Keyword(s):  
Cytochrome Oxidase ◽  
Cold Acclimation ◽  
Considerable Increase ◽  
Oxidative Capacity ◽  
Organ Mass ◽  
Cell Compartments ◽  
Brown Adipose ◽  
Desert Rodent ◽  
Shivering Thermogenesis

To determine the effects of cold acclimation on the oxidative capacity of different tissues and their possible role in nonshivering thermogenesis (NST) in a desert rodent, the gerbil (Gerbillus campestris), measurements of cytochrome oxidase activity (COX) were performed on homogenates of liver, brown adipose tissue (BAT), and subsarcolemmal (SS) and intermyofibrillar (IMF) fractions of skeletal muscle. Total organ mass was also measured. Gerbils were maintained either at thermoneutrality (TN) or cold [4 degrees C, ambient temperature (Ta)] for 4 (CA4) or 8 (CA8) wk. A comparative study was made with mice (Mus musculus). Total and relative masses of BAT increased significantly in both gerbils and mice during cold acclimation, whereas muscle mass decreased in CA4 gerbils. Specific and total COX (TCOX) increased in the three tissues. A considerable increase (+170%, P less than 0.05) of TCOX and protein content in liver of CA4 gerbils compared with controls was observed, whereas no significant changes occurred in liver of CA4 mice. In muscle, an increase of TCOX in SS and a reduction in IMF cell compartments were noted. The increase in BAT oxidative capacity in CA4 gerbils represented only a small portion of that in liver (36%) and in SS fraction of muscle (41%) at the same stage of acclimation. The ability of the three tissues to contribute to components of thermogenesis in vivo was evaluated. The sum of oxidative capacity of the three tissues was largely above the peak metabolic rate (PMR), whereas that of muscle exceeded maximum shivering thermogenesis, which developed both in TN and CA4 gerbils.(ABSTRACT TRUNCATED AT 250 WORDS)

Changes in the Adenyl Cyclase System of Skeletal Muscle of Cold-Acclimated Rats

1974 ◽  
Vol 52 (3) ◽  
pp. 176-180 ◽  
Author(s):  
Michelle Muirhead ◽  
Jean Himms-Hagen
Keyword(s):  
Skeletal Muscle ◽  
Plasma Membrane ◽  
Cold Acclimation ◽  
Metabolic Response ◽  
Adenyl Cyclase ◽  
Nonshivering Thermogenesis ◽  
Receptor System ◽  
Adenyl Cyclase System ◽  
Shivering Thermogenesis ◽  
Stimulation Of

No change could be detected in the adenyl cylase system (basal activity, noradrenaline-stimulated activity, adrenaline-stimulated activity, fluoride-stimulated activity) of skeletal muscle of cold-acclimated rats. It is concluded that the enhancement of metabolic response to noradrenaline during cold-acclimation, which occurs principally in skeletal muscle, can not be attributed to an alteration in this component of the receptor system for noradrenaline.An increase in the activity of the catecholamine-stimulated and fluoride-stimulated adenyl cyclase of skeletal muscle occurs during the 1st week of exposure to cold and has disappeared by the time the rats are fully acclimated. This increase coincides with the period of shivering thermogenesis rather than with the development of nonshivering thermogenesis; it may be related to the intense and repeated stimulation of plasma membrane associated with shivering.

Fever: exchange of shivering by nonshivering pyrogenesis in cold-acclimated guinea pigs

1976 ◽  
Vol 40 (1) ◽  
pp. 29-34 ◽  
Author(s):  
C. M. Blatteis
Keyword(s):  
Cold Acclimation ◽  
Guinea Pigs ◽  
Salmonella Enteritidis ◽  
Total Duration ◽  
Maximum Height ◽  
Ambient Temperatures ◽  
Thermal Environments ◽  
Before And After ◽  
Two Temperature ◽  
Shivering Thermogenesis

The pyrogenic response of adult, unanesthetized guinea pigs to 2 mug/kg iv of Salmonella enteritidis endotoxin was measured at 27 and 7 degrees C ambient temperatures, both before and after an 8-wk exposure to 7 degrees C. There were no significant differences between the onset, maximum height, and total duration of the fevers produced before and after cold acclimation in both thermal environments. However, in 27 degrees C, before cold acclimation, fever production was associated with vigorous shivering activity; two temperature maxima typically developed. After cold acclimation, visible shivering was not detectable during pyrogenesis; moreover, only a single maximum occurred, culminating during the interval between the two rises previously. In 7 degrees C, shivering occurred in both the non-cold- and cold-acclimated endotoxin-treated guinea pigs, but the increase in oxygen consumption was significantly greater in the latter. These results indicated, therefore, that nonshivering (NST) replaces shivering thermogenesis (ST) in a thermoneutral, while ST is added onto NST in a cold, environment in cold-acclimated guinea pigs in supplying the necessary heat for fever production, and that these effects involve alterations in the character of the febrile course.

Marker Trait Association for Autumn Cold Acclimation and Growth Rhythm in Pinus sylvestris

2003 ◽  
Vol 18 (1) ◽  
pp. 29-38 ◽  
Author(s):  
Reza Yazdani ◽  
Jan-erik Nilsson ◽  
Christophe Plomion ◽  
Gaurov Mathur
Keyword(s):  
Pinus Sylvestris ◽  
Cold Acclimation ◽  
Growth Rhythm ◽  
Trait Association
Sign in / Sign up

Export Citation Format

Share Document