scholarly journals Cell scientist to watch – Binyam Mogessie

2021 ◽  
Vol 134 (7) ◽  
Keyword(s):  
Chromosome Segregation ◽  
Cell Biology ◽  
Royal Society ◽  
Independent Research ◽  
Max Planck ◽  
Cellular Mechanisms ◽  
The Uk ◽  
University Of Bristol ◽  
The University ◽  
Mammalian Eggs

ABSTRACT Binyam Mogessie was born and raised in Ethiopia. He moved to Germany in 2004, where he studied biochemistry and cell biology at Jacobs University Bremen. He then moved to the UK for his PhD with Anne Straube, first at the Marie Curie Research Institute in Surrey and later at the Centre for Mechanochemical Cell Biology in Warwick, where he investigated the cellular mechanisms that organise the microtubule cytoskeleton during skeletal muscle differentiation. After receiving his PhD in cell biology from the University of London, he joined the laboratory of Melina Schuh in 2012 as a postdoc at the MRC-LMB in Cambridge (and later at the Max Planck Institute in Göttingen, Germany), where he discovered a function of the actin cytoskeleton in accurate chromosome segregation and the prevention of aneuploidy in mammalian eggs. Binyam established his independent research laboratory at the University of Bristol, School of Biochemistry in 2018, where he is a Wellcome Trust and Royal Society Sir Henry Dale fellow and HFSP Young Investigator. He also received a Seed Award from the Wellcome Trust and funding from the Rosetrees Trust and Royal Society. His lab is investigating actin- and microtubule-based cytoskeletal ensembles that promote healthy egg development and embryogenesis in mammals.

scholarly journals Arthur Mannering Tyndall, 1881-1961

1962 ◽  
Vol 8 ◽  
pp. 159-165 ◽  
Keyword(s):  
Private School ◽  
Royal Society ◽  
Research And Teaching ◽  
Physical Laboratory ◽  
University College ◽  
The Subject ◽  
University Of Bristol ◽  
The University ◽  
The City ◽  
Outstanding Teacher

Arthur Mannering Tyndall was a man who played a leading part in the establishment of research and teaching in physics in one of the newer universities of this country. His whole career was spent in the University of Bristol, where he was Lecturer, Professor and for a while Acting ViceChancellor, and his part in guiding the development of Bristol from a small university college to a great university was clear to all who knew him. He presided over the building and development of the H. H. Wills Physical Laboratory, and his leadership brought it from its small beginnings to its subsequent achievements. His own work, for which he was elected to the Fellowship of the Royal Society, was on the mobility of gaseous ions. Arthur Tyndall was born in Bristol on 18 September 1881. He was educated at a private school in Bristol where no science was taught, except a smattering of chemistry in the last two terms. Nonetheless he entered University College, obtaining the only scholarship offered annually by the City of Bristol for study in that college and intending to make his career in chemistry. However, when brought into contact with Professor Arthur Chattock, an outstanding teacher on the subject, he decided to switch to physics; he always expressed the warmest gratitude for the inspiration that he had received from him. He graduated with second class honours in the external London examination in 1903. In that year he was appointed Assistant Lecturer, was promoted to Lecturer in 1907, and became Lecturer in the University when the University College became a university in 1909. During this time he served under Professor A. P. Chattock, but Chattock retired in 1910 at the age of 50 and Tyndall became acting head of the department. Then, with the outbreak of war, he left the University to run an army radiological department in Hampshire.

scholarly journals Cell scientist to watch – Stefanie Redemann

2021 ◽  
Vol 134 (23) ◽  
Keyword(s):  
Cell Biology ◽  
Electron Tomography ◽  
Max Planck ◽  
Spindle Positioning ◽  
Doctorate Degree ◽  
School Of Medicine ◽  
Interdisciplinary Approaches ◽  
Approaches To Study ◽  
Virginia School ◽  
The University

ABSTRACT Stefanie Redemann studied Biology at Darmstadt Technical University, followed by a Master's at EMBL in Heidelberg, Germany. She then pursued a PhD in the labs of Tony Hyman and Jonathon Howard at the Max Planck Institute of Cell Biology and Genetics in Dresden, where she investigated the role of the actomyosin cortex in force generation and spindle positioning. After obtaining her doctorate degree in 2009, she joined the lab of Thomas Müller-Reichert at the Medical Theoretical Center in Dresden to work on reconstructing the mitotic spindle using electron tomography. Stefanie started her independent research group in 2018 at the University of Virginia School of Medicine, where she is using interdisciplinary approaches to study spindle assembly and chromosome segregation in both mitosis and meiosis.

scholarly journals Public engagement with science: Ways of thinking and practicing

2011 ◽  
pp. 45-51
Author(s):  
Elizabeth Stevenson
Keyword(s):  
Public Engagement ◽  
Work Practice ◽  
Education Institution ◽  
Effective Work ◽  
Research And Teaching ◽  
Public Engagement With Science ◽  
Primary Focus ◽  
The Uk ◽  
University Of Bristol ◽  
The University

The primary focus of the Higher Education Institution (HEI) is the generation and dissemination of knowledge. This knowledge is generated and shared throughout the research community and to students specifically enrolled in university programmes. Public engagement with science enables and ensures the generation and sharing of knowledge throughout a wider community.Public engagement with science has enjoyed an increasingly heightened profile in recent years with six „Beacons for Public Engagement‟1 being established across HEIs in the UK, including a National Co-ordinating Centre for Public Engagement2 hosted between the University of Bristol and the University of the West of England In addition, public engagement is a component in the „Pathways to Impact‟ statements3 which have been introduced into all RCUK research funding applications.However public engagement, and in particular public engagement with science, can often be perceived as an add-on or „Cinderella‟ activity to be undertaken only by the dedicated and often only in their own time. This paper argues that public engagement with science is a legitimate area of academic practice in HEIs which complements and extends research and teaching. The paper outlines key principles which underpin public engagement with science and describes effective work practice

scholarly journals Synthetic biology goes live

2013 ◽  
Vol 35 (2) ◽  
pp. 54-57 ◽  
Author(s):  
Dek Woolfson
Keyword(s):  
Synthetic Biology ◽  
Royal Society ◽  
Think Tank ◽  
The Future ◽  
The Subject ◽  
University Of Bristol ◽  
The University

On 14 November last year, the Biochemical Society, the Royal Society of Chemistry, the think-tank BioCentre and the University of Bristol co-hosted a debate on synthetic biology, which was webcast live. Dek Woolfson co-chaired the event from Bristol. Here are his reflections and conclusions from the evening, including some advice on how we might approach the broader issues of the subject and events like this in the future.

scholarly journals Comparing the Views on Problem-Based Learning from Medical Education Students in Zhengzhou University in China and the University of Bristol in the UK

2020 ◽  
Vol 14 (1) ◽  
pp. 28
Author(s):  
Xiaoyin Liu
Keyword(s):  
Group Discussion ◽  
Medical Knowledge ◽  
Problem Based Learning ◽  
Deep Understanding ◽  
Structured Interviews ◽  
Clinical Thinking ◽  
Student Centred Learning ◽  
The Uk ◽  
University Of Bristol ◽  
The University

Problem-based learning (PBL), as a student-centred learning method, refers to students actively participating in a group scenario to solve open-end problems. This study aims to compare the students’ attitudes on PBL in Zhengzhou University and the University of Bristol. This study adopts qualitative methods. By conducting semi-structured interviews with eight participants, four from Zhengzhou University and the others from the University of Bristol. Overall, the results of the study indicated that students from both two universities are overall satisfied with PBL because of its contribution to deeper understanding of medical knowledge and skill development and they all think that the quality of group discussion and the efficiency of PBL classes need to be improved. In terms of the different views from two universities, when it comes to the biggest benefit of PBL, students from Zhengzhou University are more likely to choose clinical thinking, while students from the University of Bristol are more satisfied with the deep understanding on medical knowledge. Unexpectedly, although Zhengzhou University has implemented PBL for fewer years than the University of Bristol, students are more satisfied with and motivated in PBL classes than those of the University of Bristol.

Substituted Benzenes: The Subba Reddy Synthesis of 7-Desmethoxyfusarentin

2015 ◽  
Author(s):  
Douglass F. Taber
Keyword(s):  
Ethyl Cyanoacetate ◽  
Strong Acid ◽  
State University ◽  
Max Planck ◽  
University Of Texas ◽  
Ru Catalyst ◽  
Aryl Ketones ◽  
Peking University ◽  
University Of Bristol ◽  
The University

Andrey P. A ntonchick of the Max-Planck-Institut Dortmund devised (Org. Lett. 2012, 14, 5518) a protocol for the direct amination of an arene 1 to give the amide 3. Douglass A. Klumpp of Northern University showed (Tetrahedron Lett. 2012, 53, 4779) that under strong acid conditions, an arene 4 could be carboxylated to give the amide 6. Eiji Tayama of Niigata University coupled (Tetrahedron Lett. 2012, 53, 5159) an arene 7 with the α-diazo ester 8 to give 9. Guy C. Lloyd-Jones and Christopher A. Russell of the University of Bristol activated (Science 2012, 337, 1644) the aryl silane 11 to give an intermediate that coupled with the arene 10 to give 12. Ram A. Vishwakarma and Sandip P. Bharate of the Indian Institute of Integrative Medicine effected (Tetrahedron Lett. 2012, 53, 5958) ipso nitration of an areneboronic acid 13 to give 14. Stephen L. Buchwald of MIT coupled (J. Am. Chem. Soc. 2012, 134, 11132) sodium isocyanate with the aryl chloride 15 (aryl triflates also worked well) to give the isocyanate 16, which could be coupled with phenol to give the carbamate or carried onto the unsymmetrical urea. Zhengwu Shen of the Shanghai University of Traditional Chinese Medicine used (Org. Lett. 2012, 14, 3644) ethyl cyanoacetate 18 as the donor for the conversion of the aryl bromide 17 to the nitrile 19. Kuo Chu Hwang of the National Tsig Hua University showed (Adv. Synth. Catal. 2012, 354, 3421) that under the stimulation of blue LED light the Castro-Stephens coupling of 20 with 21 proceeded efficiently at room temperature. Lutz Ackermann of the Georg-August-Universität Göttingen employed (Org. Lett. 2012, 14, 4210) a Ru catalyst to oxidize the amide 23 to the phenol 24. Both Professor Ackermann (Org. Lett. 2012, 14, 6206) and Guangbin Dong of the University of Texas (Angew. Chem. Int. Ed. 2012, 51, 13075) described related work on the ortho hydroxylation of aryl ketones. George A. Kraus of Iowa State University rearranged (Tetrahedron Lett. 2012, 53, 7072) the aryl benzyl ether 25 to the phenol 26. The synthetic utility of the triazene 27 was demonstrated (Angew. Chem. Int. Ed. 2012, 51, 7242) by Yong Huang of the Shenzen Graduate School of Peking University.

C–O Ring Construction: The Martín and Martín Synthesis of Teurilene

2017 ◽  
Author(s):  
Tristan H. Lambert
Keyword(s):  
Phenylboronic Acid ◽  
Gold Catalysis ◽  
State University ◽  
Max Planck ◽  
Amberlyst 15 ◽  
Colorado State University ◽  
University Of Toronto ◽  
Palladium Catalyzed ◽  
University Of Bristol ◽  
The University

Benjamin List at the Max-Planck-Institute in Mülheim reported (Angew. Chem. Int. Ed. 2013, 52, 3490) that the chiral phosphoric acid TRIP catalyzed the asymmet­ric SN2-type intramolecular etherification of 1 to produce tetrahydrofuran 2 with a selectivity factor of 82. The coupling of alkenol 3 with 4 to give the α-arylated tetra­hydropyran 5 via a method that combined gold catalysis and photoredox catalysis was disclosed (J. Am. Chem. Soc. 2013, 135, 5505) by Frank Glorius at Westfälische Wilhelms-Universität Münster. Mark Lautens at the University of Toronto reported (Org. Lett. 2013, 15, 1148) the conversion of cyclohexanedione 6 and phenylboronic acid to bicyclic ether 8 using rhodium catalysis in the presence of dienyl ligand 7. Propargylic ether 9 was found (Org. Lett. 2013, 15, 2926) by John P. Wolfe at the University of Michigan to undergo conversion to furanone 10 upon treatment with dibutylboron triflate and Hünig’s base followed by oxidation with hydrogen peroxide. Tomislav Rovis at Colorado State University demonstrated (Chem. Sci. 2013, 4, 1668) that the spirocyclic compound 13 could be prepared in enantioenriched form from 11 by a photoisomerization- coupled Stetter reaction using carbene catalyst 12. Antonio C. B. Burtoloso at the University of São Paulo reported (Org. Lett. 2013, 15, 2434) the conversion of ketone 14 to lactone 15 using samarium(II) iodide and methyl acrylate. The merger of diketone 16 and pyrone 17 in the presence of Amberlyst-15 to pro­duce (−)- tenuipyrone 18 was disclosed (Org. Lett. 2013, 15, 6) by Rongbiao Tong at the Hong Kong University of Science and Technology. Joanne E. Harvey at Victoria University of Wellington in New Zealand found (Org. Lett. 2013, 15, 2430) that tricy­clic ether 20 could be generated efficiently from dihydropyran 19 and pyrone 17 via a palladium-catalyzed double allylic alkylation cascade. Two rings and four stereocenters were generated in the construction of bicyclic ether 23 from dienol 21 and acetal 22 via a Lewis acid-mediated cascade, as reported (Org. Lett. 2013, 15, 2046) by Christine L. Willis at the University of Bristol.

Edward Fawcett 1867-1942

1943 ◽  
Vol 4 (12) ◽  
pp. 325-328
Keyword(s):  
Royal Society ◽  
Human Anatomy ◽  
Accurate Data ◽  
Abdominal Aneurism ◽  
Laboratory Assistant ◽  
University Of Bristol ◽  
The University

Professor Edward Fawcett, who held the chair of human anatomy in the University of Bristol for forty-one years (1893-1934), and was elected to the Royal Society in 1923, died suddenly as he walked up Lower Park Row, Bristol, on 23 September 1942, in his seventy-sixth year. Just before his collapse in the street, he had climbed a flight of steps (‘Christmas Steps’); it was found that death was due to the rupture of an abdominal aneurism which had escaped diagnosis. He was fair in colouring, stood about six feet in height, with an erect carriage, body and limbs being well proportioned; he excelled in both cricket and at golf. He had exceptional manipulative skill, a gift which served him well in his chosen profession, particularly when he came to reconstruct enlarged models of embryonic and foetal skulls from serial microscopic sections, for in his earlier years he had to be laboratory assistant as well as professor. Carpentry was a pastime, so was photography, which in his retired years assisted him to make accurate records of archaeological features of the churches of surrounding counties—Gloucester, Somerset, and Wilts. He was a man of action rather than of speech; he preferred to let his models and photographs speak for him. Generalizations did not attract him; his aim in life was to provide accurate data to serve as a foundation for generalizations, the drawing of which he was content to leave to others. He had the uncommon faculty of using both hands independently when illustrating his lectures by drawings on the blackboard. Edward Fawcett was the son of Thomas Fawcett, B.A., of Little Blencoe, near Penrith, where he was born, 18 May 1867.

Finding Law in the 21st Century: An Introduction to the SOSIG Law Gateway

2001 ◽  
Vol 29 (2) ◽  
pp. 360-382 ◽  
Author(s):  
Steven Whittle
Keyword(s):  
Support Service ◽  
Resource Discovery ◽  
The Internet ◽  
Legal Information ◽  
Legal Studies ◽  
The Law ◽  
The Uk ◽  
New Research ◽  
University Of Bristol ◽  
The University

This paper provides an introduction to the SOSIG (Social Science Information Gateway) Law Gateway a web based descriptive database of high quality legal information resources on the Internet (www.sosig.ac.uk/law). The Law Gateway is a new research support service being developed by the Institute of Advanced Legal Studies (University of London) in partnership with the University of Bristol as part of the UK's Resource Discovery Network initiative. The project seeks to provide access to the expanding range of global legal materials now being delivered over the Internet. In effect, the Law Gateway aims to offer the UK and international legal communities appropriate new ways to find, assess and access law in the new century.

scholarly journals Cell scientist to watch – Christine Faulkner

2020 ◽  
Vol 133 (24) ◽  
pp. jcs256826
Keyword(s):  
Cell Biology ◽  
Cell Communication ◽  
Plant Cells ◽  
Postdoctoral Position ◽  
Molecule Transport ◽  
University Of Edinburgh ◽  
The Uk ◽  
And Function ◽  
The University ◽  
Sydney Australia

ABSTRACTChristine Faulkner pursued her undergraduate degree at the University of Sydney, Australia. She then joined Robyn Overall's research group at the same institution to obtain her PhD in molecular and cell biology, where she characterised plasmodesmata, which are connection channels between plant cells that allow for communication and molecule transport. In 2005, Christine moved to the UK to continue studying plasmodesmata characterisation and function, as well as trying to understand their link to infection outcomes. Her first postdoctoral position was with Karl Oparka at the University of Edinburgh, followed by a second at the John Innes Centre in Norwich with Professor Andrew Maule. She subsequently joined the lab of Silke Robatzek at The Sainsbury Laboratory, also in Norwich, before starting an independent fellowship at Oxford Brookes University, in Oxford, in 2012. In December 2013, Christine returned to the John Innes Centre to establish her own lab. In 2016, she was awarded an ERC Consolidator grant. Her lab is trying to understand how cell–cell communication occurs in plants, focusing on plasmodesmata, and how this process is crucial for regulation of the plant immune response.

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