scholarly journals Basal-type lumenogenesis in extraembryonic endoderm stem cells models the early visceral endoderm

2019 ◽  
Vol 132 (19) ◽  
pp. jcs230607 ◽  
Author(s):  
Minjae Kim ◽  
Yixiang Zhong ◽  
Kyoung Hwa Jung ◽  
Young Gyu Chai ◽  
Bert Binas
Keyword(s):  
Stem Cells ◽  
Visceral Endoderm ◽  
Extraembryonic Endoderm ◽  
Basal Type

scholarly journals OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells

2016 ◽  
Vol 6 (4) ◽  
pp. 447-455 ◽  
Author(s):  
Anthony Parenti ◽  
Michael A. Halbisen ◽  
Kai Wang ◽  
Keith Latham ◽  
Amy Ralston
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Extraembryonic Endoderm ◽  
Induced Pluripotent

Investigation of cell lineage and differentiation in the extraembryonic endoderm of the mouse embryo

Development ◽  
1982 ◽  
Vol 68 (1) ◽  
pp. 175-198
Author(s):  
R. L. Gardner
Keyword(s):  
Inner Cell Mass ◽  
Cell Mass ◽  
Cell Lineage ◽  
Early Embryo ◽  
Visceral Endoderm ◽  
Primitive Endoderm ◽  
Developmental Potential ◽  
Extraembryonic Endoderm ◽  
Parietal Endoderm ◽  
Endodermal Cells

The technique of injecting genetically labelled cells into blastocysts was used in an attempt to determine whether the parietal and visceral endoderm originate from the same or different cell populations in the early embryo. When the developmental potential of 5th day primitive ectoderm and primitive endoderm cells was compared thus, only the latter were found to colonize the extraembryonic endoderm. Furthermore, single primitive endoderm cells yielded unequivocal colonization of both the parietal and the visceral endoderm in a proportion of chimaeras. However, in the majority of primitive endodermal chimaeras, donor cells were detected in the parietal endoderm only, cases of exclusively visceral colonization being rare. Visceral endoderm cells from 6th and 7th day post-implantation embryos also exhibited a striking tendency to contribute exclusively to the parietal endoderm following blastocyst injection. The above findings lend no support to a recent proposal that parietal and visceral endoderm are derived from different populations of inner cell mass cells. Rather, they suggest that the two extraembryonic endoderm layers originate from a common pool of primitive endoderm cells whose direction of differentiation depends on their interactions with non-endodermal cells.

Cell interactions and endoderm differentiation in cultured mouse embryos

Development ◽  
1981 ◽  
Vol 62 (1) ◽  
pp. 379-394
Author(s):  
Brigid L. M. Hogan ◽  
Rita Tilly
Keyword(s):  
Basement Membrane ◽  
Mouse Embryo ◽  
Cell Lineage ◽  
Giant Cells ◽  
Visceral Endoderm ◽  
Extraembryonic Endoderm ◽  
Type Iv ◽  
The Matrix ◽  
Parietal Endoderm

Morphological and biochemical evidence is presented that the visceral extraembryonic endoderm of the 6·5-day mouse embryo will differentiate into parietal endoderm when cultured in contact with extraembryonic ectoderm undergoing transition into trophoblast giant cells. Egg cylinders from 6·5-day embryos were dissected into embryonic and extraembryonic halves and cultured in suspension in vitro for up to 7 days. After 4 days, the endoderm cells of the extraembryonic fragments morphologically resemble parietal endoderm, are associated with a thick basement membrane and synthesize large amounts of the matrix proteins laminin and Type IV procollagen. A similar transition in phenotype is not seen in the endoderm of embryonic fragments, nor in visceral extraembryonic endoderm cells cultured in isolation. In another series of experiments, complete egg cylinders were dissected free of visceral endoderm ovei lying the extraembryonic ectoderm and then cultured in vitro. The visceral endoderm cells which recolonize the surface of the extraembryonic ectoderm develop a parietal endoderm phenotype and lay down a thick basement membrane. These results suggest that the differentiation of the extraembryonic endoderm of the early mouse embryo into visceral and parietal phenotypes can be influenced by local cell—cell or cell—substrate interactions, and is not determined solely by cell lineage.

scholarly journals eXtraembryonic ENdoderm (XEN) Stem Cells Produce Factors that Activate Heart Formation

PLoS ONE ◽  
2010 ◽  
Vol 5 (10) ◽  
pp. e13446 ◽  
Author(s):  
Kemar Brown ◽  
Michael Xavier Doss ◽  
Stephanie Legros ◽  
Jérôme Artus ◽  
Anna-Katerina Hadjantonakis ◽  
...  
Keyword(s):  
Stem Cells ◽  
Extraembryonic Endoderm ◽  
Heart Formation

scholarly journals Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells

2013 ◽  
Vol 8 (6) ◽  
pp. 1028-1041 ◽  
Author(s):  
Kathy K Niakan ◽  
Nadine Schrode ◽  
Lily T Y Cho ◽  
Anna-Katerina Hadjantonakis
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Mouse Embryos ◽  
Extraembryonic Endoderm

scholarly journals Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells

Stem Cells ◽  
2012 ◽  
Vol 30 (3) ◽  
pp. 461-470 ◽  
Author(s):  
Xuezhu Feng ◽  
Jiuchun Zhang ◽  
Kimberly Smuga-Otto ◽  
Shulan Tian ◽  
Junying Yu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Protein Kinase C ◽  
Embryonic Stem Cells ◽  
Protein Kinase ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Endoderm Differentiation ◽  
Extraembryonic Endoderm ◽  
Kinase C

scholarly journals Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Saqib S. Sachani ◽  
Lauren S. Landschoot ◽  
Liyue Zhang ◽  
Carlee R. White ◽  
William A. MacDonald ◽  
...  
Keyword(s):  
Stem Cells ◽  
Extraembryonic Endoderm
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