scholarly journals Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxia

2012 ◽  
Vol 125 (24) ◽  
pp. 5950-5954 ◽  
Author(s):  
E. A. Craig ◽  
J. D. Weber ◽  
V. S. Spiegelman
Keyword(s):  
Cell Proliferation ◽  
Metastatic Melanoma ◽  
Melanoma Cell ◽  
Binding Protein ◽  
Metastatic Melanoma Cell ◽  
Mrna Binding Protein ◽  
Melanoma Cell Proliferation ◽  
Mrna Binding ◽  
Proliferation And Invasion

scholarly journals The effect of a novel frizzled 8-related antiproliferative factor on in vitro carcinoma and melanoma cell proliferation and invasion

2011 ◽  
Vol 30 (5) ◽  
pp. 1849-1864 ◽  
Author(s):  
Kristopher R. Koch ◽  
Chen-Ou Zhang ◽  
Piotr Kaczmarek ◽  
Joseph Barchi ◽  
Li Guo ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Melanoma Cell ◽  
Melanoma Cell Proliferation ◽  
Proliferation And Invasion

scholarly journals Hsa_circ_0026134 expression promoted TRIM25- and IGF2BP3-mediated hepatocellular carcinoma cell proliferation and invasion via sponging miR-127-5p

2020 ◽  
Vol 40 (7) ◽  
Author(s):  
Wei Zhang ◽  
Liang Zhu ◽  
Guowei Yang ◽  
Bo Zhou ◽  
Jianhua Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Cell Lines ◽  
Luciferase Reporter ◽  
Circular Rnas ◽  
Down Regulation ◽  
Mrna Binding Protein ◽  
New Treatment ◽  
Mrna Binding ◽  
Proliferation And Invasion

Abstract Increasing evidence shows that circular RNAs (circRNAs) play a regulatory role in cancer. In the present study, we aimed to investigate the characteristics and effects of hsa_circ_0026134 in hepatocellular carcinoma (HCC). We investigated hsa_circ_0026134 expression in 20 pairs of clinical tissues from HCC patients; expression of hsa_circ_0026134 in different cell lines; effect of hsa_circ_0026134 on proliferation and invasion of HCC cell lines; and the regulatory mechanisms and interactions among hsa_circ_0026134, miR-127-5p, tripartite motif-containing protein 25 (TRIM25) and insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3). hsa_circ_0026134 expression was increased in HCC samples and cell lines. Down-regulation of hsa_circ_0026134 attenuated HCC cell proliferation and metastatic properties. Micro (mi)RNA (miR)-127-5p was sponged by hsa_circ_0026134. Rescue experiments indicated that inhibition of miR-127-5p expression promoted cell proliferation and invasion even after hsa_circ_0026134 silencing. TRIM25 and IGF2BP3 were targets of miR-127-5p. Overexpression of TRIM25 or IGF2BP3 promoted cell proliferation and invasion in cells overexpressing miR-127-5p. Down-regulation of hsa_circ_0026134 suppressed TRIM25- and IGF2BP3-mediated HCC cell proliferation and invasion via promotion of miR-127-5p expression, which have been confirmed by luciferase reporter assay. The present study provides a new treatment target for HCC.

scholarly journals 7‑dehydrocholesterol suppresses melanoma cell proliferation and invasion via Akt1/NF‑κB signaling

2020 ◽  
Vol 20 (6) ◽  
pp. 1-1
Author(s):  
Jia Liu ◽  
Feiliang Zhong ◽  
Lei Cao ◽  
Ruiying Zhu ◽  
Junze Qu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Melanoma Cell ◽  
Nf Kappa B ◽  
Melanoma Cell Proliferation ◽  
Proliferation And Invasion

scholarly journals MiR-144 Inhibits Uveal Melanoma Cell Proliferation and Invasion by Regulating c-Met Expression

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0124428 ◽  
Author(s):  
Lei Sun ◽  
Guangqing Bian ◽  
ZhaoJun Meng ◽  
Guangfu Dang ◽  
DeJing Shi ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Uveal Melanoma ◽  
Melanoma Cell ◽  
Uveal Melanoma Cell ◽  
Melanoma Cell Proliferation ◽  
Proliferation And Invasion

Ligand Bound Fatty Acid Binding Protein 7 (FABP7) Drives Melanoma Cell Proliferation Via Modulation of Wnt/β-Catenin Signaling

2021 ◽  
Vol 38 (3) ◽  
pp. 479-490
Author(s):  
Banlanjo Abdulaziz Umaru ◽  
Yoshiteru Kagawa ◽  
Subrata Kumar Shil ◽  
Naoki Arakawa ◽  
Yijun Pan ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Fatty Acid ◽  
Melanoma Cell ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Melanoma Cell Proliferation
Sign in / Sign up

Export Citation Format

Share Document