scholarly journals Depletion of histone deacetylase 3 antagonizes PI3K-mediated overgrowth ofDrosophilaorgans through the acetylation of histone H4 at lysine 16

2012 ◽  
Vol 125 (22) ◽  
pp. 5369-5378 ◽  
Author(s):  
Wen-Wen Lv ◽  
Hui-Min Wei ◽  
Da-Liang Wang ◽  
Jian-Quan Ni ◽  
Fang-Lin Sun
Keyword(s):  
Histone Deacetylase ◽  
Histone H4 ◽  
Histone Deacetylase 3

Depletion of histone deacetylase 3 antagonizes PI3K-mediated overgrowth of Drosophila organs through the acetylation of histone H4 at lysine 16

Development ◽  
2013 ◽  
Vol 140 (4) ◽  
pp. e407-e407
Author(s):  
W.-W. Lv ◽  
H.-M. Wei ◽  
D.-L. Wang ◽  
J.-Q. Ni ◽  
F.-L. Sun
Keyword(s):  
Histone Deacetylase ◽  
Histone H4 ◽  
Histone Deacetylase 3

scholarly journals The critical roles of histone deacetylase 3 in the pathogenesis of solid organ injury

2021 ◽  
Vol 12 (8) ◽  
Author(s):  
Li Ning ◽  
Xiong Rui ◽  
Wang Bo ◽  
Geng Qing
Keyword(s):  
Histone Deacetylase ◽  
Chromatin Remodeling ◽  
Current Knowledge ◽  
Organ Injury ◽  
Solid Organ ◽  
Solid Organ Injury ◽  
Histone Deacetylase 3 ◽  
Physiological Conditions ◽  
Inflammatory Conditions ◽  
Therapeutic Value

AbstractHistone deacetylase 3 (HDAC3) plays a crucial role in chromatin remodeling, which, in turn, regulates gene transcription. Hence, HDAC3 has been implicated in various diseases, including ischemic injury, fibrosis, neurodegeneration, infections, and inflammatory conditions. In addition, HDAC3 plays vital roles under physiological conditions by regulating circadian rhythms, metabolism, and development. In this review, we summarize the current knowledge of the physiological functions of HDAC3 and its role in organ injury. We also discuss the therapeutic value of HDAC3 in various diseases.

scholarly journals Histone deacetylase 3 as a novel therapeutic target in multiple myeloma

Leukemia ◽  
2013 ◽  
Vol 28 (3) ◽  
pp. 680-689 ◽  
Author(s):  
J Minami ◽  
R Suzuki ◽  
R Mazitschek ◽  
G Gorgun ◽  
B Ghosh ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Histone Deacetylase ◽  
Therapeutic Target ◽  
Histone Deacetylase 3 ◽  
Novel Therapeutic

scholarly journals miR-326-Histone Deacetylase-3 Feedback Loop Regulates the Invasion and Tumorigenic and Angiogenic Response to Anti-cancer Drugs

2014 ◽  
Vol 289 (40) ◽  
pp. 28019-28039 ◽  
Author(s):  
Youngmi Kim ◽  
Hyuna Kim ◽  
Hyunmi Park ◽  
Deokbum Park ◽  
Hansoo Lee ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Feedback Loop ◽  
Cancer Drugs ◽  
Histone Deacetylase 3 ◽  
Angiogenic Response ◽  
Anti Cancer

scholarly journals Decreased levels of autoantibody against histone deacetylase 3 in patients with systemic sclerosis

Autoimmunity ◽  
2009 ◽  
Vol 42 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Yutaka Kuwatsuka ◽  
Fumihide Ogawa ◽  
Yohei Iwata ◽  
Kazuhiro Komura ◽  
Eiji Muroi ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Histone Deacetylase ◽  
Histone Deacetylase 3
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