A mathematically modelled cytogel cortex exhibits periodic Ca++-modulated contraction cycles seen in Physarum shuttle streaming

Development ◽  
1984 ◽  
Vol 83 (Supplement) ◽  
pp. 261-287
Author(s):  
Garrett M. Odell

If each of many cells of an embryo (or different zones in a single cell) possess identical active cytogel machinery, having the ‘right’ mechanochemical response properties, then the collective interaction among those identical participants leads automatically to the globally coherent tissue deformations seen in embryogenesis, and to shuttle streaming in the plasmodial slime mould Physarum polycephalum. Biologically plausible, and experimentally verifiable hypotheses are proposed concerning how the tension generated by a strand of cytogel is determined by the deformation it suffers and by the concentration of a contraction trigger chemical, Ca2+, whose kinetics involve coupling to mechanical strain. The consequences of these hypotheses, deduced by solving the appropriate differential equation systems numerically, and displayed in computer-animated films, closely imitate diverse tissue deformation events seen in developing embryos. The same hypotheses on cytogel behaviour are used to model a thick-walled Physarum vein segment, and two such segments are set up to be able to pump endoplasm back and forth between them. Under certain conditions, this model exhibits spontaneous rhythmic mechanochemical oscillations, many features of which correlate well with shuttle streaming in Physarum. Small gradual variations of parameters, presumably under genetic control, are shown to cause abrupt and biologically interesting bifurcations of the qualitative behaviour of the model.

2020 ◽  
pp. 40-50
Author(s):  
Boris Morgenroth ◽  
Thomas Stark ◽  
Julian Pelster ◽  
Harjeet Singh Bola

Optimization of process steam requirement in order to maximize sugar recovery and export power along with manpower optimization is a must for sugar factories to survive under difficult conditions and to earn additional revenues. The process steam demand of greenfield and revamped plants has been reduced to levels of 32–38% from originally more than 50% steam on cane in the case of the brownfield plants. In addition, significant improvement in the power requirement of the plants has been achieved. Bagasse drying offers a good potential to improve the power export. Different available concepts are compared with a focus on bagasse steam drying and low temperature bagasse drying. In order to set up an optimized highly efficient plant or to optimize an existing plant to achieve competitive benchmarks, good process design and the right equipment selection are very important. Experience has been gained with multiple stage or double effect crystallization in the beet sugar industry offering further steam optimization potential. Vapour recompression is also an option to substitute live steam by electrical power. This even provides options to reduce the steam demand from the power plant for the sugar process down to zero. Key aspects concerning the process design and equipment selection are described.


1970 ◽  
Vol 22 ◽  
Author(s):  
R. Goossens ◽  
J. De Schuyter

In  this article, we tried to perform the drawing of forest maps, together with  the calculations involved, automatically by means of relatively simple aids.      The computer unit used is an office computer Olivetti P203. As an example  the growing stock (in m3/ha) was mapped out. The proper inventory in the field is done  according to the classical method by means of a previously fixed network of  squares (70,7 m x 70,7 m), which corresponds to two plots a ha.     The quantity which is measured and mapped out (in this case the growing  stock) is in a similar form not very useful in mapping. Therefore a division  in classes (Ku) numbered from 0 to 9, is set up. An appropriate program  calculates for a certain number of points within this elementary square, to which  class they have to be assigned, whereas the typewriter prints the  corresponding code number on the right place.     Fig. 1 and the formulas (1), (2) and (3) represent the principle o[ the  calculations while fig. 2A and B reproduce the results printed by the  typewriter for a elementary square of respective 1” X 1” and 2” X 2”. The  whole of similar network of squares eventually results in a basical document,  on which the existing forest map with an adapted scale is laid (see appendix  3) and the class limits are drawn.     If desirable, the scale may be adapted when the forest map under discussion  is definitely reproduced.


Author(s):  
David K. Jones

The fight over an exchange had a very different dynamic in New Mexico because there were no loud voices on the right calling for the state to reject control. Republican Governor Susanna Martinez supported retaining control, but strongly preferred a governance model that allowed insurers to serve on the board of directors and limited the degree of oversight by the board on the types of plans that could be sold on the exchange. Governor Martinez vetoed legislation in 2011 that would have set up a different model of an exchange. Institutional quirks meant the legislature did not have the opportunity to weigh in again for two years, until 2013. By this point it was too late and the state had to rely on the federal website despite passing legislation to run its own exchange.


2000 ◽  
Vol 49 (3) ◽  
pp. 621-642 ◽  
Author(s):  
Anne Looijestijn-Clearie

InCentros Ltd and Erhvers-og Selskabsstyrelesen (hereinafter Centros),1 the European Court of Justice ruled that it is contrary to Article 52 (now Article 432) and Article 58 (now Article 48) of the EC Treaty for the authorities of a member State (in casu Denmark) to refuse to register a branch of a company formed under the law of another member State (in casu the United Kingdom) in which it has its registered office, even if the company concerned has never conducted any business in the latter State and intends to carry out its entire business in the State in which the branch is to be set up. By avoiding the need to form a company there it would thus evade the application of the rules governing the provision for and the paying-up of a minimum share capital in force in that State. According to the Court, this does not, however, prevent the authorities of the member State in which the branch is to be set up from adopting appropriate measures for preventing or penalising fraud, either with regard to the company itself, if need be in co-operation with the member State in which it was formed, or with regard to its members, where it has been determined that they are in fact attempting, by means of the formation of a company, to evade their obligations towards creditors established in the territory of the member State of the branch.


Author(s):  
Ane Bang-Kittilsen ◽  
Terje Midtbø

AbstractGeologists struggle to communicate the uncertainty that arise when mapping and interpreting the geological subsurface. Today, open data sharing policies make new value of geological information possible for a broader user group of non-experts. It is crucial to develop standard methods for visualizing uncertainty to increase the usability of geological information. In this study, a web experiment was set up to analyze whether and how different design choices influence the sense of uncertainty. Also, questions about the intuitiveness of symbols were asked. Two-hundred ten participants from different countries completed the experiment, both experts and non-experts in geology. Traditional visualization techniques in geology, like dashed lines, dotted lines and question mark, were tested. In addition, other visualizations were tested, such as hatched area and variations of symbol size, zoom levels and reference information. The results show that design choices have an impact on the participants’ assessment of uncertainty. The experts inquire about crucial information if it is not present. The results also suggest that when visualizing uncertainty, all the elements in the representation, and specifically the line and area symbols that delineate and colour the features, must work together to make the right impression.


1944 ◽  
Vol 38 (2) ◽  
pp. 266-288
Author(s):  
Robert E. Cushman

On February 15, 1943, Wiley B. Rutledge, Jr., a judge of the United States Circuit Court of Appeals for the District of Columbia, took the seat on the Supreme Court vacated by the resignation in October, 1942, of Mr. Justice Byrnes. There were no other changes in the Court's personnel. Disagreement among the justices abated somewhat. In only a dozen cases of importance did either four or three justices dissent, as against some thirty cases in the last term. The Court overruled two earlier decisions, both recent; and the reversal in each case was made possible by the vote of Mr. Justice Rutledge.A. QUESTIONS OF NATIONAL POWER1. WAR POWER-CIVIL VERSUS MILITARY AUTHORITYWest Coast Curfew Applied to Japanese-American Citizens. In February, 1942, the President issued Executive Order No. 9066, which authorized the creation of military areas from which any or all persons might be excluded and with respect to which the right of persons to enter, remain in, or leave should be subject to such regulations as the military authorities might prescribe. On March 2, the entire West Coast to an average depth of forty miles was set up as Military Area No. 1 by the Commanding General in that area, and the intention was announced to evacuate from it persons of suspected loyalty, alien enemies, and all persons, aliens and citizens alike, of Japanese ancestry.


2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Rome Samanta ◽  
Satyabrata Datta

Abstract Within the Type-I seesaw mechanism, quantum effects of the right-handed (RH) neutrinos in the gravitational background lead to an asymmetric propagation of lepton and anti-leptons which induces a Ricci scalar and neutrino Dirac-Yukawa coupling dependent chemical potential and therefore a lepton asymmetry in equilibrium. At high temperature, lepton number violating scattering processes try to maintain a dynamically generated lepton asymmetry in equilibrium. However, when the temperature drops down, the interactions become weaker, and the asymmetry freezes out. The frozen out asymmetry can act as a pre-existing asymmetry prior to the standard Fukugita-Yanagida leptogenesis phase (Ti ∼ Mi, where Mi is the mass of ith RH neutrino). It is then natural to consider the viability of gravitational leptogenesis for a given RH mass spectrum which is not consistent with successful leptogenesis from decays. Primary threat to this gravity-induced lepton asymmetry to be able to successfully reproduce the observed baryon-to-photon ratio is the lepton number violating washout processes at Ti ∼ Mi. In a minimal seesaw set up with two RH neutrinos, these washout processes are strong enough to erase a pre-existing asymmetry of significant magnitude. We show that when effects of flavour on the washout processes are taken into account, the mechanism opens up the possibility of successful leptogenesis (gravitational) for a mass spectrum M2 » 109GeV » M1 with M1 ≳ 6.3 × 106 GeV. We then briefly discuss how, in general, the mechanism leaves its imprints on the low energy CP phases and absolute light neutrino mass scale.


Curationis ◽  
1980 ◽  
Vol 3 (3) ◽  
Author(s):  
V. Ehlers

A committee was set up in Britain in 1975 under the Chairmanship of Mrs Peggy Jay to look into the staffing of mental handicapped residential care in the National Health Service. Part of the task was to consider the Briggs Committee’s recommendation that “… a new caring profession for the mentally handicapped should emerge gradually”. The findings and recommendations of the committee were however radical and far-reaching, involving an enormous shift in financial resources and causing much concern and outcry from the nursing profession which considered the new category of care given as a threat to their existence.


2018 ◽  
Vol 50 (4) ◽  
pp. 627-648 ◽  
Author(s):  
Katayoun Shafiee

AbstractThe Iranian government's decision to nationalize its British-controlled oil industry in 1951 was a landmark case in international law. The Anglo-Iranian Oil Company and the Iranian government clashed over whether international authorities had the right to arbitrate for them in disputes over the terms of the oil concession. Scholarship in Middle East studies has overlooked the role of concession terms in shaping political disputes in the 20th century. Rather than seeing legal studies of the oil industry on one side and power struggles and resources on the other, this article examines international court proceedings at The Hague to argue that Anglo-Iranian oil transformed international law. Novel mechanisms of economic and legal governance, set up to deal with an expanded community of nation-states, worked as techniques of political power that equipped the oil corporation with the power to associate Iran's oil with foreign control while generating new forms of law and contract that undermined resource nationalism.


2017 ◽  
Vol 7 (3) ◽  
pp. 1-19
Author(s):  
Farzana Quoquab ◽  
Shazwani Binti Ahmad ◽  
Wan Nurul Syazwani Binti Wan Danial ◽  
Jihad Mohammad

Subject area This case can be used in marketing management as well as consumer behaviour courses. Study level/applicability This case is suitable to use in advanced undergraduate levels, MBA and MSc in marketing courses that cover topics related to market segmentation and marketing mix strategies. Case overview This case highlights the dilemma of an entrepreneur and a manager of a restaurant who were to take a decision about the sustainability of their restaurant business. Balqis Restaurant was owned by Danny who was a retiree from Telekom Malaysia. He wanted to open a restaurant business after he came back from his long holiday trip. He conducted market research to find a suitable place to open his Arabic restaurant. He assigned Waleed Masood Abdullah as the manager of Balqis Restaurant. Finally, in June 2010, he opened his long awaited restaurant at Gombak, Kuala Lumpur. The restaurant was known as Qasar before the name was changed to Balqis in 2015 because of copyright issues related to Saba’ restaurant at Cyberjaya. The restaurant was well managed under Danny’s supervision for 4 years and successfully won customers’ hearts and loyalty before he decided to give full responsibility to Waleed in March 2014. Danny trusted Waleed because he taught and trained him. However, under Waleed’s management, Balqis started to lose its customers. Waleed also started to branch out the restaurant to different places in different states; one in Ipoh, and the other in Perak. He invested much money on renovation for all three branches, but one of the restaurants closed down in September 2014. This is because of the fact that they could no longer bear the cost of operations for the restaurant. However, he failed to learn from the mistake; they set up another restaurant, which was in Kuantan, in the same month. The sales were not that encouraging but it did show gradual improvement; yet, they once again sold it to another Arab businessman. Waleed realized his failure in managing the restaurant business in August 2015. He again opted to open another new branch which was questioned by Danny. He was in a rush to open it by the end of December 2015 to ensure that the additional profits from the current restaurants could cover the variables costs if the new restaurants were launched. Based on that, the owner had to make a decision about whether a new branch should be opened or whether they should just retain their restaurant in Gombak. Expected learning outcomes The learning objectives of using this case are as follows. 1. Knowledge enhancement: to help students in understanding the problems faced by a restaurant in expanding its market; to make students aware that a properly blended marketing mix is the key to business success and to broaden students’ views and understanding in targeting the proper market segment in formulating an effective marketing strategy. 2. Skills building: to be able to identify the best marketing strategic decisions to manage the restaurant business for its survival and to develop students’ ability to analyse the existing situation to come up with a viable and effective solution. 3. Attitudinal: to help the students to have intellectual openness in accepting different ways of finding solutions for a particular problem and to assist students in making the right move at the right time. Supplementary materials Teaching Notes are available for educators only. Please contact your library to gain login details or email [email protected] to request teaching notes. Subject code CSS 8: Marketing.


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