Computer modelling of cell division during development using a topological approach

Development ◽  
1984 ◽  
Vol 83 (Supplement) ◽  
pp. 233-259
Author(s):  
Robert Ransom ◽  
Raymond J. Matela

Development in multicellular animals consists of a constant progression of cell division, differentiation and morphogenesis. Our understanding of the relationship between division and the acquisition of shape and form is not well understood, and this paper describes a computer representation of cell division processes with possible applications to the modelling of developmental events. This representation is not itself a model in the true sense, but is a scaffolding onto which a set of model assumptions and parameters can be built. We discuss one such set of assumptions, used to model cell sorting, describe the extension of the framework to represent sheets of cells in three dimensions, and make some observations on the incorporation of mechanical forces into the representation.

2021 ◽  
pp. 1-21
Author(s):  
Émilie Lapointe ◽  
Christian Vandenberghe

Abstract This article looks at the relationship between psychological contract breach and voluntary turnover among newcomers, using supervisor trustworthiness as a mediator and negative affectivity as a moderator. Relying on data from 243 newcomers, psychological contract breach was found to be negatively related to the three dimensions of supervisor trustworthiness, i.e., ability, benevolence, and integrity. Supervisor integrity further mediated a positive relationship between psychological contract breach and voluntary turnover measured 8 months later. Psychological contract breach interacted with negative affectivity such that it was less negatively related to dimensions of supervisor trustworthiness at high levels of negative affectivity. The indirect relationship of psychological contract breach to voluntary turnover as mediated by supervisor integrity was also weaker at high levels of negative affectivity. We discuss the implications of these findings for research and practice.


2008 ◽  
Vol 101 (14) ◽  
Author(s):  
M. Shane Hutson ◽  
G. Wayne Brodland ◽  
Justina Yang ◽  
Denis Viens

2016 ◽  
Vol 57 (4) ◽  
pp. 411-427 ◽  
Author(s):  
Jane Elizabeth Pizzolato ◽  
Avery B. Olson

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Augusto Dalmoro Costa ◽  
Aurora Carneiro Zen ◽  
Everson dos Santos Spindler

PurposeThe purpose of this paper is to investigate the relationship between family succession, professionalization and internationalization in family businesses within the Brazilian context.Design/methodology/approachThe paper presents a multiple-case study method with three Brazilian family businesses that have at least two generations of the owning family involved in the business and an international presence of at least three years. In-depth interviews and secondary data were undertaken with family and non-family members of each case.FindingsThe authors' results show that a family business can boost its internationalization by introducing both succession planning and professionalization on international activities. As family members tend to be more risk-averse and focused on keeping the family business within the family, professionalization is a way of improving the firm's ability to expand internationally. This process tends to lead to lower performance by the firm for the first few months or the first year after the investment, but afterward, international performance tends to grow exponentially.Originality/valueOnly a few studies have been concerned on the relationship of these three dimensions. Thus, the research takes into account that professionalization and succession lead family businesses to improve their internationalization strategies.


2015 ◽  
Vol 10 (12) ◽  
pp. 103 ◽  
Author(s):  
Ayad F. Altememi ◽  
Imad A. Hassouneh ◽  
Shaker Jarallah Alkshali

This study aims to identify the relationship between the creative capabilities of workers in 5-star hotels in the city of Amman and their cultural intelligence. In its measurement of the creative capabilities as an independent variable, the study adopted a scale consisting of three dimensions, namely: fluency, flexibility and originality. Whereas it relied in measuring the cultural intelligence as a dependent variable, on a scale consisting of three dimensions, namely: knowledge (cognition), motivation and behavior. The study was conducted on a sample of (258) workers currently working in these hotels. The required particulars for this study were collected through a specially prepared questionnaire for this purpose after having reviewed multi previous studies. The sample was distributed according to the simple random sample mechanism. The study revealed that there is a significant positive relationship between the dimensions of creative capabilities of workers in such hotels and their cultural intelligence. The study also included a set of recommendations and mechanisms that can be applied by the managements of these hotels to tackle some aspects of the dimensions constituting the cultural intelligence of workers.


1991 ◽  
Vol 118 (2) ◽  
pp. 275-293
Author(s):  
J. Roberts ◽  
N. J. Greenwood ◽  
J. D. Harsant ◽  
M. G. Sturmey

ABSTRACTThe paper was prepared by an informal working party as an introduction to an open forum discussion. It considers from several viewpoints the relationship between the actuary and the computer, both in its function as a calculating tool and as a data processing and storage medium. The paper considers in detail the requirements of the Appointed Actuary for adequate data, the problems of allocating and pricing for computer costs and the increasing uses of computer modelling in financial reporting. The place of computer literacy in actuarial education, future developments and standards are also considered.


2018 ◽  
Vol 25 (8) ◽  
pp. 3225-3237 ◽  
Author(s):  
Surendra Kumar Sia ◽  
Pravakar Duari

PurposeThe purpose of this paper is to examine the contribution of agentic work behaviour and decision-making authority (DMA) to thriving at work and, more importantly, the moderating role of DMA in the relationship between agentic behaviour and thriving.Design/methodology/approachThe study has been carried out upon a random sample of 330 employees below supervisory level from manufacturing companies located at Odisha (a state located at the eastern part of India). After verifying the significance of correlation among the study variables through Pearson’s product moment correlation, moderated regression analyses were carried out to examine the independent contribution of agentic work behaviour and DMA to thriving as well as the moderating contribution of DMA towards thriving.FindingsResults reveal that the three dimensions of agentic work behaviour, namely, task focus, exploration and heedful relation, have a direct positive contribution towards thriving at workplace. As far as the moderation is concerned, it is observed that the thriving level is higher for the employees having high DMA irrespective of the level of agentic work behaviour at each dimension.Research limitations/implicationsThe findings imply for designing interventions to enhance task focus, super-ordinate relationship and interest for learning. In addition, the organisations should provide autonomy to employees for decision making.Originality/valueThe study is first of its kind in the Indian context upon employee thriving. In this study, the authors have not only investigated the separate independent contribution of agentic behaviour and DMA, but also their interacting contribution to employee thriving.


2018 ◽  
Vol 34 (2) ◽  
pp. 398 ◽  
Author(s):  
Cristina Reche ◽  
Cristina De Francisco ◽  
Alejandro Martínez-Rodríguez ◽  
Almudena Ros-Martínez

<p align="left">The aim of the study was to determine the prevalence of exercise dependence and athlete burnout and their relationship between them and among demographic and sport characteristics in 449 athletes, 320 males and 129 females (Age: <em>M</em>= 19.71, <em>SD</em>= 6.62). All of them replied the Spanish versions of Exercise Dependence Scale-Revised (EDS-R) and reduced version of Athlete Burnout Questionnaire (ABQ). The results showed a risk of exercise dependence in 8.7% of the athletes, with statistically significant differences in age (a greater exercise dependence was found in athletes under the age of 18 years old), not in gender, sport dedication and type of sport. Regarding burnout, measured through its three dimensions, the data showed 4% for emotional/physical exhaustion (EFE) and 4.9% for sport devaluation (SD) and reduced sense of accomplishment (RSA). Men and team-sport athletes showed a greater RSA. Men and athletes over the age of 18 also showed more DS. As for sport dedication, participants who spent less time training had higher levels of RSA, whereas those who dedicated more time, had higher levels of EFE. Finally, the relationship between exercise dependence and burnout showed that all dimensions of burnout correlated positively with exercise dependence. </p>


2017 ◽  
Vol 9 (4) ◽  
pp. 769-776 ◽  
Author(s):  
Jennifer Collins ◽  
Robin Ersing ◽  
Amy Polen

Abstract This study conducted in Florida examines the relationship between an individual’s social connections and their decision to evacuate during a hurricane warning. Using Hurricane Matthew in 2016 as a case study, a survey was conducted on two groups (those who evacuated and those who did not), assessing one’s social connections considering three dimensions: dependability, density, and diversity. These factors, in addition to socioeconomic variables (e.g., age, race, education), were used to better define a picture for what influences evacuation decision-making. To avoid memory decay, the surveys were completed at the time of the evacuation for those who evacuated and immediately after the passage of Matthew for those who did not evacuate. It was concluded, through statistical analyses, that the perceived dependability of a person’s social connections (i.e., their perceived access to resources and support) played a significant role in the decision to evacuate or not, with non-evacuees having more dependable relationships and having a tightknit community they can rely on during a storm event. On the other hand, the density and diversity of peoples’ social connections did not significantly impact the decision to evacuate. This study has important implications for adding to the knowledge base on community-based sustainable disaster preparedness and resilience.


2017 ◽  
Vol 4 (4) ◽  
Author(s):  
Mandakini Rathore ◽  
Dr. Chandrani Sen

The purpose of the present paper was to analyse the relationship between perceived organizational justice and organizational commitment on IT sector (India). The research was conducted on 90 employees working in IT sector. A Correlation design was deployed to analyse the data. The three dimensions of organizational justice- procedural, distributive and interactional were positively correlated with organizational commitment wherein distributive justice contributed the most to commitment.


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