Epithelial Regeneration and Wound Healing in the Oesophagus of the Cat

Development ◽  
1958 ◽  
Vol 6 (2) ◽  
pp. 288-296
Author(s):  
R. M. H. McMinn ◽  
F. R. Johnson

Saint in 1929 documented the experimental studies that had been carried out up to that date on the healing of oesophageal wounds. The reported observations dealt with the relatively long-term results, and little attention was paid to the early changes that occurred during the period immediately following the infliction of the wound. Recently, Malm (1951) made observations following surgical experiments on the oesophagus in dogs, but again no reference was made to the early changes in epithelium or connective tissue. The most recent experimental work on oesophageal healing appears to be that of Picard, Henry, Cotte, & Inglesakis (1956), but their interest lay in the repair of muscular tissue. The present investigation was designed to study the behaviour of epithelium and connective tissue in the cat's oesophagus, following the removal of small areas of mucous membrane. Routine histological methods were supplemented by a series of histochemical studies on both the normal and regenerating tissues.

2010 ◽  
pp. S59-S64
Author(s):  
P Scheer ◽  
P Svoboda ◽  
M Sepši ◽  
K Janečková ◽  
J Doubek

The long-term electrocardiographic recording with retrospective evaluation (Holter system) has been widely used not only in cardiology, but also in other disciplines of internal medicine and in pharmaceutical research. The Holter system can be used in mini-pig, sheep, dog, cat, rabbit, ferret, and rat. In this paper hardware, software, and anesthesia requirements are summarized with respect to the experimental work with various species. As the Holter systems work in bipolar mode, the use of bipolar leads in sagittal and transversal planes has been proved to be the most appropriate because of large amplitude of QRS complex and uncomplicated consequent automatic analysis of the record. In conclusion, Holter electrocardiography represents a simple and applicable method for monitoring the electrical activity of the heart in small animals’ experimental studies.


2009 ◽  
Vol 16 (2) ◽  
pp. 15-21
Author(s):  
I M Pichkhadze ◽  
Artak Matsakovich Matsakyan ◽  
K A Kuz'menkov ◽  
A V Zhadin ◽  
A V Tsiskarashvili ◽  
...  

Basing on the results of theoretical analysis and experimental studies, biomechanical characteristics (resistance to displacement) of clavicle fragments of various length were determined. With regard for obtained data the requirements and indications to the application of various osteosynthesis techniques (transosseous, epiosseous, intramedullar) in different types of fractures were formulated. Treatment of clavicular fractures and their sequelae in accordance with biomecha-nical conception of fragments fixation was performed in 223 patients. Long term results were evaluated in 178 patients. Excellent results were achieved in 135 (75.9%) cases, good - in 26 (14.6%), satisfactory - in 10 (5.6%) and unsatisfactory - in 7 (3.9%) of cases. The results of the study showed that at observance of all biomechanical principles of bone fragments fixation it was possible to improve the outcomes of clavicular fractures treatment and to reduce the rate of complications considerably.


2020 ◽  
Author(s):  
Eeva-Stiina Tuittila ◽  
Aino Korrensalo ◽  
Anna Laine ◽  
Nicola Kokkonen ◽  
Lauri Mehtätalo ◽  
...  

<p>Recent paleoecological studies have demonstrated an ongoing drying trend in temperate and boreal peatlands in Europe and in Canada. This drying is likely to alter vegetation and carbon gas exchange with atmosphere. However, to revel the expected change in carbon gas dynamics associated with decrease in water level experimental studies and long-term monitoring are needed. In here we present results from long term experiment in Finland where the impact of water level drawdown (WLD) of ~10 cm on three different peatland sites, two fens and a bog, has been studied since year 2000.</p><p> </p><p>Response to WLD differed between the three ecosystem types. In the nutrient rich fen WLD initiated rapid directional succession from sedge dominated system to the dominance of woody species. In the poor fen changes were less drastic: Initially WLD benefitted dwarf scrubs already present at the site, later they were overtaken by pines.  Sedges as a group hold their position but Carex species were replaced by Eriophorum. Similarly to sedges, in the moss layer proportions of different Sphagnum moss species changed. Bog vegetation was more stable than fen vegetation.</p><p> </p><p>In all the ecosystems methane emissions decreased directly after WLD. In contrast, the response of CO2 dynamics was more complex. While long term net ecosystem exchange decreased to lower level than in controls in all studied ecosystems, the response of photosynthesis and respiration differed between the three ecosystems and between short term and long term. Results show how the response of peatlands to climate change is diverse and emphasize the need to understand what factors regulate the stability and resilience of peatland functioning.</p>


2016 ◽  
Vol 88 (1) ◽  
Author(s):  
Aleksandra Iljin ◽  
Edward Lewandowicz ◽  
Bogusław Antoszewski ◽  
Tomasz Zieliński

Abstractwas to present our experience with post-auricular tube flap (ptf) and clinical evaluation of the results following auricular helical rim reconstruction with this technique in patients after trauma.We analyzed the results in 12 patients who underwent three-staged auricular helical rim reconstruction with ptf following trauma in the Department of Plastic, Reconstructive and Aesthetic Surgery between 2005-2014. The patients were followed-up for at least 1 year. We evaluated early and long-term results after surgery including plastic surgeon’s and patient’s opinion.Postoperative results were satisfactory (very good) in 10 cases, both in the opinion of the plastic surgeon and patients. Transient venous congestion of the helix occurred in two cases (16.6%). This complication did not have any influence on estimation of the results after surgery. Delayed wound healing in the poles of the reconstructed helical edge, as well as non-aesthetic helical scars with imperfections of helical rim, were seen in another two patients (16.6%).1. Post-auricular tube flap reconstructions after helical rim trauma allowed for complete restoration of contour, size and orientation of the helix and the whole operated ear, which confirms the efficiency of the applied technique. 2. Reconstructive surgery with post-auricular tube flap in patients with auricular helical rim defects contributed to postoperative satisfaction in both patients and doctors’ estimations.


Author(s):  
Khalid S Al-Hamdan

Tooth sensitivity is a major concern following gingival recession. Stable long-term results are necessary for the management of this condition. Here, we present a case report with the aim of validating the utilisation of a connective tissue graft to replace a restorative material over the root surface for a long term. A 36-year-old female patient presented with the chief complaint of sensitivity in her lower right (#43) and left (#33) canines, which were previously restored with a composite restoration. The recession type defect was Miller’s Class II. The old restoration was removed and replaced with a connective tissue graft, accompanied by a double-papilla flap. The case was followed-up for 18 years, and the results were stable during the follow-up period, with a highly satisfied patient. Based on these results, it can be reported that a connective tissue graft has highly predictable results and can be used for previously restored root surfaces. In addition, the connective tissue graft provides more stable results than does the use of a restorative material over root surfaces.


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