scholarly journals Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development

Development ◽  
2017 ◽  
Vol 144 (12) ◽  
pp. 2294-2305 ◽  
Author(s):  
Lemonia Chatzeli ◽  
Marcia Gaete ◽  
Abigail S. Tucker
Keyword(s):  
Salivary Gland ◽  
Progenitor Cells ◽  
Gland Development

scholarly journals Capability of Tissue Stem Cells to Organize into Salivary Rudiments

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Kenji Okumura ◽  
Masanori Shinohara ◽  
Fumio Endo
Keyword(s):  
Stem Cells ◽  
Salivary Gland ◽  
Salivary Glands ◽  
Progenitor Cells ◽  
Duct Cell ◽  
Branching Morphogenesis ◽  
Embryonic Cells ◽  
Gland Development ◽  
Salivary Epithelia ◽  
Pseudoglandular Stage

Branching morphogenesis (BrM), an essential step for salivary gland development, requires epithelial-mesenchymal interactions. BrM is impaired when the surrounding mesenchyme is detached from the salivary epithelium during the pseudoglandular stage. It is believed that the salivary mesenchyme is indispensable for BrM, however, an extracellular matrix gel with exogenous EGF can be used as a substitute for the mesenchyme during BrM in the developing salivary epithelium. Stem/progenitor cells isolated from salivary glands in humans and rodents can be classified as mesenchymal stem cell-like, bone-marrow-derived, duct cell-like, and embryonic epithelium-like cells. Salivary-gland-derived progenitor (SGP) cells isolated from duct-ligated rats, mice, and swine submandibular glands share similar characteristics, including intracellular laminin andα6β1-integrin expression, similar to the embryonic salivary epithelia during the pseudoglandular stage. Progenitor cells also isolated from human salivary glands (human SGP cells) having the same characteristics differentiate into hepatocyte-like cells when transplanted into the liver. Similar to the dissociated embryonic salivary epithelium, human SGP cells aggregate to self-organize into branching organ-like structures on Matrigel plus exogenous EGF. These results suggest the possibility that tissue stem cells organize rudiment-like structures, and the embryonic cells that organize into whole tissues during development are preserved even in adult tissues.

Effect of methoprene and 20-hydroxyecdysone on salivary gland development of the lone star tick, Amblyomma americanum (L.)

1989 ◽  
Vol 35 (4) ◽  
pp. 313-320 ◽  
Author(s):  
Kent S. Shelby ◽  
Katherine M. Kocan ◽  
John A. Bantle ◽  
John R. Sauer
Keyword(s):  
Salivary Gland ◽  
Amblyomma Americanum ◽  
Lone Star Tick ◽  
Gland Development

scholarly journals Functional genetic characterization of salivary gland development in Aedes aegypti

EvoDevo ◽  
2013 ◽  
Vol 4 (1) ◽  
pp. 9 ◽  
Author(s):  
Chilinh Nguyen ◽  
Emily Andrews ◽  
Christy Le ◽  
Longhua Sun ◽  
Zeinab Annan ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Aedes Aegypti ◽  
Genetic Characterization ◽  
Gland Development

scholarly journals Salivary gland development: A template for regeneration

2014 ◽  
Vol 25-26 ◽  
pp. 52-60 ◽  
Author(s):  
Vaishali N. Patel ◽  
Matthew P. Hoffman
Keyword(s):  
Salivary Gland ◽  
Gland Development

Mesenchymal control over elongating and branching morphogenesis in salivary gland development

Development ◽  
1981 ◽  
Vol 66 (1) ◽  
pp. 209-221
Author(s):  
Hiroyuki Nogawa ◽  
Takeo Mizuno
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Submaxillary Gland ◽  
Branching Morphogenesis ◽  
Mouse Submaxillary Gland ◽  
Gland Development

Recombination of the epithelium and mesenchyme between quail anterior submaxillary gland (elongating type) and quail anterior lingual or mouse submaxillary gland (branching type) was effected in vitro to clarify whether the elongating morphogenesis was directed by the epithelial or the mesenchymal component. Quail anterior submaxillary epithelium recombined with quail anterior lingual or mouse submaxillary mesenchyme came to branch. Conversely, quail anterior lingual or 12-day mouse submaxillary epithelium recombined with quail anterior submaxillary mesenchyme came to elongate, though the mesenchyme was less effective with 13-day mouse submaxillary epithelium. These results suggest that the elongating or branching morphogenesis of quail salivary glands is controlled by the mesenchyme.

Analysis of the mechanism in salivary gland development using gene database

2018 ◽  
Vol 60 (4) ◽  
pp. 83-86 ◽  
Author(s):  
Takayoshi Sakai ◽  
Hitomi Ono Minagi ◽  
Aya Obana-Koshino ◽  
Manabu Sakai
Keyword(s):  
Salivary Gland ◽  
Gene Database ◽  
Gland Development

scholarly journals Diverse progenitor cells preserve salivary gland ductal architecture after radiation-induced damage

Development ◽  
2018 ◽  
Vol 145 (21) ◽  
pp. dev166363 ◽  
Author(s):  
Alison J. May ◽  
Noel Cruz-Pacheco ◽  
Elaine Emmerson ◽  
Eliza A. Gaylord ◽  
Kerstin Seidel ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Progenitor Cells ◽  
Radiation Induced

Salivary gland development in the blowfly,Calliphora erythrocephala

1976 ◽  
Vol 149 (4) ◽  
pp. 459-482 ◽  
Author(s):  
Michael J. Berridge ◽  
Brij L. Gupta ◽  
James L. Oschman ◽  
Betty J. Wall
Keyword(s):  
Salivary Gland ◽  
Calliphora Erythrocephala ◽  
Gland Development

Organ shape in the Drosophila salivary gland is controlled by regulated, sequential internalization of the primordia

Development ◽  
2000 ◽  
Vol 127 (4) ◽  
pp. 679-691 ◽  
Author(s):  
M.M. Myat ◽  
D.J. Andrew
Keyword(s):  
Salivary Gland ◽  
Cell Shape ◽  
Cell Adhesion Molecule ◽  
Scanning Electron Micrographs ◽  
Final Shape ◽  
A Cell ◽  
Gland Development ◽  
Aberrant Tubes ◽  
Shape Changes ◽  
Multiple Stages

During Drosophila development, the salivary primordia are internalized to form the salivary gland tubes. By analyzing immuno-stained histological sections and scanning electron micrographs of multiple stages of salivary gland development, we show that internalization occurs in a defined series of steps, involves coordinated cell shape changes and begins with the dorsal-posterior cells of the primordia. The ordered pattern of internalization is critical for the final shape of the salivary gland. In embryos mutant for huckebein (hkb), which encodes a transcription factor, or faint sausage (fas), which encodes a cell adhesion molecule, internalization begins in the center of the primordia, and completely aberrant tubes are formed. The sequential expression of hkb in selected cells of the primordia presages the sequence of cell movements. We propose that hkb dictates the initial site of internalization, the order in which invagination progresses and, consequently, the final shape of the organ. We propose that fas is required for hkb-dependent signaling events that coordinate internalization.

Sign in / Sign up

Export Citation Format

Share Document