Mumps Virus Infection of the Pregnant Hamster

Development ◽  
1963 ◽  
Vol 11 (4) ◽  
pp. 659-665
Author(s):  
Vergil H. Ferm ◽  
Lawrence Kilham

The objective of our present studies has been to follow the course of mumps virus when injected intravenously into pregnant hamsters during early stages of gestation, in order to determine possible relations to fetal disease and/or malformations. Several considerations prompted the selection of mumps virus for these investigations. One was that, while rubella (Gregg, 1941) and cytomegalic inclusion body disease (Weller & Hanshaw, 1962) have been the only two viruses shown to have a definite cause-effect relation in the etiology of human congenital malformations, there has been a continuing suspicion that mumps virus may also act as a teratogenic agent in human pregnancy (Kaye & Reaney, 1962; Blattner & Heys, 1961; Hyatt, 1961). A second reason was that mumps virus has a natural pathogenicity for hamsters (Kilham & Overman, 1953). In addition, this agent is capable of infecting women at term, the strain used in present experiments having been obtained from human milk a few days post-partum (Kilham, 1951).

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1587
Author(s):  
Yasmin Amaral ◽  
Leila Silva ◽  
Fernanda Soares ◽  
Daniele Marano ◽  
Sylvia Nehab ◽  
...  

Background: To evaluate the potential factors associated with the nutritional composition of human milk of puerperal women. Methods: cross-sectional study, conducted between March 2016 and August 2017, with 107 women, selected in a Tertiary Health Care Tertiary Health Facility of the Unified Health System (SUS) in the Municipality of Rio de Janeiro. Data were collected two months after delivery. The dependent variable of the study was the nutritional composition of human milk. We divided the independent variables into hierarchical levels: distal (age, schooling, parity and pregestational nutritional status), intermediate (number of prenatal visits and gestational weight gain) and proximal (alcohol consumption, smoking, diabetes mellitus and hypertension). For data analysis, we applied the multiple linear regression, centered on the hierarchical model. Only the variables associated with the nutritional composition of breast milk remained in the final model at a 5% level of significance. Results: The nutritional composition of human milk yielded by women with pregestational overweight, smokers and hypertensive had higher amounts of lipids and energy. Conversely, women with gestational weight gain below the recommended had lower amounts of these components. Conclusion: The evaluation of factors associated with the nutritional composition of human milk is extremely important to assist post-partum care practices. In this study, we observed that lipid and energy contents were associated to pregestational nutritional status, gestational weight gain, smoking and hypertension.


Neurology ◽  
2015 ◽  
Vol 86 (3) ◽  
pp. 211-217 ◽  
Author(s):  
Akinori Uruha ◽  
Satoru Noguchi ◽  
Yukiko K. Hayashi ◽  
Rie S. Tsuburaya ◽  
Takahiro Yonekawa ◽  
...  

PEDIATRICS ◽  
1956 ◽  
Vol 18 (3) ◽  
pp. 362-368
Author(s):  
Ruth T. Gross ◽  
Lincoln E. Moses

Four hundred seven healthy, full-term infants were divided into three groups and fed, respectively, a formula of evaporated milk and water with 5% carbohydrate; human milk; and a special modified evaporated milk designed to simulate human milk. No other foods were added to the diet. A comparison of the three groups was made, based on weight gains from birth to the end of the first 4 weeks. The conclusions refer only to weight gains; no attempt was made to determine the superiority of any particular diet. The data show no significant differences in the 4-week weight gains among the three groups of infants, although sensitive statistical methods could be validly applied to the problem. These methods are explained. The authors wish to emphasize the many variables which must be taken into account in a study of this sort; the necessity for careful selection of valid statistical methods; the importance of critical clinical judgement in the evaluation of the results.


1985 ◽  
Vol 6 (2) ◽  
pp. 237-239 ◽  
Author(s):  
A. Rotilio ◽  
G. Salar ◽  
C. Dollo ◽  
C. Ori ◽  
A. Carteri

2010 ◽  
Vol 6 (11) ◽  
pp. e1001198 ◽  
Author(s):  
John J. Miles ◽  
Anna M. Bulek ◽  
David K. Cole ◽  
Emma Gostick ◽  
Andrea J. A. Schauenburg ◽  
...  

BMJ ◽  
1965 ◽  
Vol 2 (5477) ◽  
pp. 1529-1529 ◽  
Author(s):  
P. K. O'Brien ◽  
D. S. Smith ◽  
O. P. Galpin

1973 ◽  
Vol 7 (4) ◽  
pp. 520-525 ◽  
Author(s):  
R. J. Genco ◽  
T. D. Flanagan ◽  
F. G. Emmings

2003 ◽  
Vol 46 (2) ◽  
pp. 167-176 ◽  
Author(s):  
L. Panicke ◽  
E. Fischer ◽  
B. Fischer ◽  
R. Staufenbiel

Abstract. Title of the paper: Level estimation of metabolic parameters in the glucose tolerance test (GTT) of young bulls The metabolic parameters of the glucose tolerance test are suitable for an additional recommendation for the valuation of the breeding bulls before the start of the offspring’s test could be given. Very important is the level of glucose half live to the begin of lactation of the cows. The other limit is the hyperglycemias greater than 10 mmol/l (or 180 mg/dl) in the glucose level in the blood. The glucose half live measured nearly 48 minutes is comparable in the 8th week post partum in lactation of cows with the young bulls in the age one year. Their combination with the pedigree breeding value is leading to increase of information, that could be utilised to the selection of improper bulls if the present results were confirmed.


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