scholarly journals Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis

Development ◽  
2014 ◽  
Vol 141 (10) ◽  
pp. 2139-2149 ◽  
Author(s):  
D. Rebourcet ◽  
P. J. O'Shaughnessy ◽  
J.-L. Pitetti ◽  
A. Monteiro ◽  
L. O'Hara ◽  
...  
Keyword(s):  
Cell Fate ◽  
Leydig Cell ◽  
Sertoli Cells ◽  
Cell Development ◽  
Myoid Cell ◽  
Peritubular Myoid Cell

scholarly journals Sertoli Cells Maintain Leydig Cell Number and Peritubular Myoid Cell Activity in the Adult Mouse Testis

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e105687 ◽  
Author(s):  
Diane Rebourcet ◽  
Peter J. O’Shaughnessy ◽  
Ana Monteiro ◽  
Laura Milne ◽  
Lyndsey Cruickshanks ◽  
...  
Keyword(s):  
Leydig Cell ◽  
Sertoli Cells ◽  
Adult Mouse ◽  
Cell Activity ◽  
Cell Number ◽  
Mouse Testis ◽  
Myoid Cell ◽  
Peritubular Myoid Cell

scholarly journals Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0167920 ◽  
Author(s):  
Qing Wen ◽  
Yuqian Wang ◽  
Jixin Tang ◽  
C. Yan Cheng ◽  
Yi-Xun Liu
Keyword(s):  
Cell Differentiation ◽  
Sertoli Cell ◽  
Leydig Cell ◽  
Myoid Cell ◽  
Testis Development ◽  
Fetal Testis ◽  
Peritubular Myoid Cell

scholarly journals Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Sneha L. Koneru ◽  
Mark Hintze ◽  
Dimitris Katsanos ◽  
Michalis Barkoulas
Keyword(s):  
Genetic Variation ◽  
Stem Cell ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Cell Fate ◽  
Cell Development ◽  
Wnt Signalling ◽  
Single Amino Acid ◽  
Cryptic Genetic Variation ◽  
Seam Cell

AbstractA fundamental question in medical genetics is how the genetic background modifies the phenotypic outcome of mutations. We address this question by focusing on the seam cells, which display stem cell properties in the epidermis of Caenorhabditis elegans. We demonstrate that a putative null mutation in the GATA transcription factor egl-18, which is involved in seam cell fate maintenance, is more tolerated in the CB4856 isolate from Hawaii than the lab reference strain N2 from Bristol. We identify multiple quantitative trait loci (QTLs) underlying the difference in phenotype expressivity between the two isolates. These QTLs reveal cryptic genetic variation that reinforces seam cell fate through potentiating Wnt signalling. Within one QTL region, a single amino acid deletion in the heat shock protein HSP-110 in CB4856 is sufficient to modify Wnt signalling and seam cell development, highlighting that natural variation in conserved heat shock proteins can shape phenotype expressivity.

Differentiation of seminiferous tubule-associated stem cells into leydig cell and myoid cell lineages

2021 ◽  
Vol 525 ◽  
pp. 111179
Author(s):  
Xingxing Zhao ◽  
Xin Wen ◽  
Minpeng Ji ◽  
Xiaoju Guan ◽  
Panpan Chen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Leydig Cell ◽  
Seminiferous Tubule ◽  
Myoid Cell ◽  
Cell Lineages

scholarly journals Transient Hypothyroidism: Dual Effect on Adult-Type Leydig Cell and Sertoli Cell Development

2017 ◽  
Vol 8 ◽  
Author(s):  
Eddy Rijntjes ◽  
Marcos L. M. Gomes ◽  
Nina Zupanič ◽  
Hans J. M. Swarts ◽  
Jaap Keijer ◽  
...  
Keyword(s):  
Sertoli Cell ◽  
Leydig Cell ◽  
Cell Development ◽  
Dual Effect ◽  
Adult Type ◽  
Transient Hypothyroidism

Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy

2021 ◽  
Vol 415 ◽  
pp. 115440
Author(s):  
Haoni Yan ◽  
Changchang Li ◽  
Cheng Zou ◽  
Xiu Xin ◽  
Xiaoheng Li ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Leydig Cell ◽  
Cell Development ◽  
Male Rats

scholarly journals Advances in the Regulation of Epidermal Cell Development by C2H2 Zinc Finger Proteins in Plants

2021 ◽  
Vol 12 ◽  
Author(s):  
Guoliang Han ◽  
Yuxia Li ◽  
Ziqi Qiao ◽  
Chengfeng Wang ◽  
Yang Zhao ◽  
...  
Keyword(s):  
Cell Fate ◽  
Zinc Finger ◽  
Epidermal Cell ◽  
Stress Responses ◽  
Root Hairs ◽  
Zinc Finger Proteins ◽  
Cell Development ◽  
Salt Glands ◽  
Plant Adaptation ◽  
C2h2 Zinc Finger

Plant epidermal cells, such as trichomes, root hairs, salt glands, and stomata, play pivotal roles in the growth, development, and environmental adaptation of terrestrial plants. Cell fate determination, differentiation, and the formation of epidermal structures represent basic developmental processes in multicellular organisms. Increasing evidence indicates that C2H2 zinc finger proteins play important roles in regulating the development of epidermal structures in plants and plant adaptation to unfavorable environments. Here, we systematically summarize the molecular mechanism underlying the roles of C2H2 zinc finger proteins in controlling epidermal cell formation in plants, with an emphasis on trichomes, root hairs, and salt glands and their roles in plant adaptation to environmental stress. In addition, we discuss the possible roles of homologous C2H2 zinc finger proteins in trichome development in non-halophytes and salt gland development in halophytes based on bioinformatic analysis. This review provides a foundation for further study of epidermal cell development and abiotic stress responses in plants.

scholarly journals Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development

2019 ◽  
Vol 10 ◽  
Author(s):  
Lanlan Chen ◽  
Xiaoheng Li ◽  
Yiyan Wang ◽  
Tiantian Song ◽  
Huitao Li ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Leydig Cell ◽  
Cell Development ◽  
Fibroblast Growth
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