scholarly journals A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish

Development ◽  
2011 ◽  
Vol 138 (7) ◽  
pp. 1409-1419 ◽  
Author(s):  
Jason E. Fish ◽  
Joshua D. Wythe ◽  
Tong Xiao ◽  
Benoit G. Bruneau ◽  
Didier Y. R. Stainier ◽  
...  
Keyword(s):  
Tube Formation ◽  
Heart Tube ◽  
Regulatory Loop ◽  
Heart Tube Formation

scholarly journals Asymmetric Involution of the Myocardial Field Drives Heart Tube Formation in Zebrafish

2008 ◽  
Vol 102 (2) ◽  
Author(s):  
Stefan Rohr ◽  
Cécile Otten ◽  
Salim Abdelilah-Seyfried
Keyword(s):  
Tube Formation ◽  
Heart Tube ◽  
Heart Tube Formation

scholarly journals A polarized nucleus-cytoskeleton-ECM connection in migrating cardioblasts controls heart tube formation

Development ◽  
2021 ◽  
Author(s):  
Cristiana Dondi ◽  
Benjamin Bertin ◽  
Jean-Philippe Daponte ◽  
Inga Wojtowicz ◽  
Krzysztof Jagla ◽  
...  
Keyword(s):  
Expression Patterns ◽  
Tube Formation ◽  
Cardiac Cells ◽  
Collective Migration ◽  
Heart Tube ◽  
Adhesion Sites ◽  
Correct Alignment ◽  
Temporal And Spatial ◽  
Heart Tube Formation ◽  
Made In

The formation of the cardiac tube is a remarkable example of complex morphogenetic processes conserved from invertebrates to humans. It involves coordinated collective migration of contralateral rows of cardiac cells. The molecular processes underlying the specification of cardioblasts (CBs) prior to migration are well established and significant advances have been made in understanding the process of lumen formation. However, the mechanisms of collective cardiac cells migration remain elusive. Here we identified CAP and MSP300 as novel actors involved during CBs migration. They both exhibit highly similar temporal and spatial expression patterns in migrating cardiac cells and are necessary for the correct number and alignment of CBs, a prerequisite for the coordination of their collective migration. Our data suggest that CAP and MSP300 are part of a protein complex linking focal adhesion sites to nuclei via the actin cytoskeleton that maintains post-mitotic state and correct alignment of CBs.

scholarly journals Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 ◽  
Vol 11 (8) ◽  
pp. 1061-1072 ◽  
Author(s):  
J D Molkentin ◽  
Q Lin ◽  
S A Duncan ◽  
E N Olson
Keyword(s):  
Transcription Factor ◽  
Tube Formation ◽  
Heart Tube ◽  
Heart Tube Formation

scholarly journals Small heat shock protein Hsp27 is required for proper heart tube formation

genesis ◽  
2007 ◽  
Vol 45 (11) ◽  
pp. 667-678 ◽  
Author(s):  
Daniel D. Brown ◽  
Kathleen S. Christine ◽  
Christopher Showell ◽  
Frank L. Conlon
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Heat Shock Protein ◽  
Tube Formation ◽  
Heart Tube ◽  
Heart Tube Formation

scholarly journals A novel Slit–Robo–miR-218 signaling axis regulates VEGF-mediated heart tube formation in zebrafish

2010 ◽  
Vol 344 (1) ◽  
pp. 433 ◽  
Author(s):  
Stephanie Woo ◽  
Jason E. Fish ◽  
Joshua D. Wythe ◽  
Benoit B. Bruneau ◽  
Didier Y. Stainier ◽  
...  
Keyword(s):  
Tube Formation ◽  
Heart Tube ◽  
Signaling Axis ◽  
Heart Tube Formation

scholarly journals GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 ◽  
Vol 11 (8) ◽  
pp. 1048-1060 ◽  
Author(s):  
C T Kuo ◽  
E E Morrisey ◽  
R Anandappa ◽  
K Sigrist ◽  
M M Lu ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Tube Formation ◽  
Heart Tube ◽  
Heart Tube Formation
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