scholarly journals Mutations in spalt cause a severe but reversible neurodegenerative phenotype in the embryonic central nervous system of Drosophila melanogaster

Development ◽  
2002 ◽  
Vol 129 (24) ◽  
pp. 5577-5586 ◽  
Author(s):  
R. Cantera
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Drosophila Melanogaster

scholarly journals Expression of a Drosophila melanogaster acetylcholine receptor-related gene in the central nervous system.

1988 ◽  
Vol 8 (2) ◽  
pp. 778-785 ◽  
Author(s):  
S C Wadsworth ◽  
L S Rosenthal ◽  
K L Kammermeyer ◽  
M B Potter ◽  
D J Nelson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Drosophila Melanogaster ◽  
Acetylcholine Receptor ◽  
Optic Lobe ◽  
Cdna Probe ◽  
Amino Acid Sequence Homology ◽  
Gene Encoding ◽  
Salivary Gland Polytene Chromosome ◽  
The Central Nervous System

We isolated Drosophila melanogaster genomic sequences with nucleotide and amino acid sequence homology to subunits of vertebrate acetylcholine receptor by hybridization with a Torpedo acetylcholine receptor subunit cDNA probe. Five introns are present in the portion of the Drosophila gene encoding the unprocessed protein and are positionally conserved relative to the human acetylcholine receptor alpha-subunit gene. The Drosophila genomic clone hybridized to salivary gland polytene chromosome 3L within region 64B and was termed AChR64B. A 3-kilobase poly(A)-containing transcript complementary to the AChR64B clone was readily detectable by RNA blot hybridizations during midembryogenesis, during metamorphosis, and in newly enclosed adults. AChR64B transcripts were localized to the cellular regions of the central nervous system during embryonic, larval, pupal, and adult stages of development. During metamorphosis, a temporal relationship between the morphogenesis of the optic lobe and expression of AChR64B transcripts was observed.

scholarly journals Drosophila Zic family member odd-paired is needed for adult post-ecdysis maturation

Open Biology ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 190245
Author(s):  
Eléanor Simon ◽  
Sergio Fernández de la Puebla ◽  
Isabel Guerrero
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Transcription Factor ◽  
Drosophila Melanogaster ◽  
Family Member ◽  
Ectopic Expression ◽  
Functional Conservation ◽  
The Central Nervous System ◽  
Behavioural Sequence

Specific neuropeptides regulate in arthropods the shedding of the old cuticle (ecdysis) followed by maturation of the new cuticle. In Drosophila melanogaster , the last ecdysis occurs at eclosion from the pupal case, with a post-eclosion behavioural sequence that leads to wing extension, cuticle stretching and tanning. These events are highly stereotyped and are controlled by a subset of crustacean cardioactive peptide (CCAP) neurons through the expression of the neuropeptide Bursicon (Burs). We have studied the role of the transcription factor Odd-paired (Opa) during the post-eclosion period. We report that opa is expressed in the CCAP neurons of the central nervous system during various steps of the ecdysis process and in peripheral CCAP neurons innerving the larval muscles involved in adult ecdysis. We show that its downregulation alters Burs expression in the CCAP neurons. Ectopic expression of Opa, or the vertebrate homologue Zic2 , in the CCAP neurons also affects Burs expression, indicating an evolutionary functional conservation. Finally, our results show that, independently of its role in Burs regulation, Opa prevents death of CCAP neurons during larval development.

EXPRESSION ANALYSIS OF THE LINGERER GENE IN THE LARVAL CENTRAL NERVOUS SYSTEM OF DROSOPHILA MELANOGASTER

2003 ◽  
Vol 17 (2) ◽  
pp. 117-137 ◽  
Author(s):  
Hisato Kuniyoshi ◽  
Kazue Usui-Aoki ◽  
Naoto Juni ◽  
Daisuke Yamamoto
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Drosophila Melanogaster ◽  
Expression Analysis

Analysis of Hunger-Driven Gene Expression in the Drosophila melanogaster Larval Central Nervous System

2008 ◽  
Vol 25 (7) ◽  
pp. 746-752 ◽  
Author(s):  
Masasuke Ryuda ◽  
Kimio Shimada ◽  
Ryo Koyanagi ◽  
Kaoru Azumi ◽  
Teiichi Tanimura ◽  
...  
Keyword(s):  
Gene Expression ◽  
Central Nervous System ◽  
Nervous System ◽  
Drosophila Melanogaster

scholarly journals Labeling of Single Cells in the Central Nervous System of Drosophila melanogaster

10.3791/50150 ◽  
2013 ◽  
Author(s):  
Christof Rickert ◽  
Thomas Kunz ◽  
Kerri-Lee Harris ◽  
Paul Whitington ◽  
Gerhard Technau
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Drosophila Melanogaster ◽  
Single Cells ◽  
The Central Nervous System
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