scholarly journals Drosophila Regulatory factor X is necessary for ciliated sensory neuron differentiation

Development ◽  
2002 ◽  
Vol 129 (23) ◽  
pp. 5487-5498 ◽  
Author(s):  
R. Dubruille
Keyword(s):  
Sensory Neuron ◽  
Factor X ◽  
Regulatory Factor ◽  
Neuron Differentiation

scholarly journals Drosophila regulatory factor X is an embryonic type I sensory neuron marker also expressed in spermatids and in the brain of Drosophila

2001 ◽  
Vol 103 (1-2) ◽  
pp. 159-162 ◽  
Author(s):  
Camille Vandaele ◽  
Madeleine Coulon-Bublex ◽  
Pierre Couble ◽  
Bénédicte Durand
Keyword(s):  
Sensory Neuron ◽  
Type I ◽  
Factor X ◽  
Regulatory Factor ◽  
The Brain

The C. elegans Regulatory Factor X (RFX) DAF-19M Module: A Shift From General Ciliogenesis to Ciliary and Behavioral Specialization

2021 ◽  
Author(s):  
Soungyub Ahn ◽  
Heeseung Yang ◽  
Sangwon Son ◽  
Dongjun Park ◽  
Hyunsoo Yim ◽  
...  
Keyword(s):  
Factor X ◽  
Regulatory Factor ◽  
C Elegans ◽  
Behavioral Specialization

scholarly journals Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome

2021 ◽  
pp. dmm.047357
Author(s):  
Beverly A. Karpinski ◽  
Thomas M. Maynard ◽  
Corey A. Bryan ◽  
Gelila Yitsege ◽  
Anelia Horvath ◽  
...  
Keyword(s):  
Mouse Model ◽  
Neural Crest ◽  
Sensory Neuron ◽  
Cranial Nerve ◽  
22Q11.2 Deletion Syndrome ◽  
Deletion Syndrome ◽  
22Q11.2 Deletion ◽  
Neuron Differentiation ◽  
Pediatric Dysphagia ◽  
Cell Cell

22q11.2 Deletion Syndrome (22q11DS) is a neurodevelopmental disorder associated with cranial nerve anomalies and disordered oropharyngeal function including pediatric dysphagia. Using the LgDel 22q11DS mouse model, we asked whether sensory neuron differentiation in the trigeminal ganglion (CNgV) , which is essential for normal orofacial function, is disrupted. We did not detect changes in cranial placode cell translocation or neural crest migration at early stages of LgDel CNgV development. As the ganglion coalesces, however, proportions of placode-derived LgDel CNgV cells increase relative to neural crest cells. In addition, local aggregation of placode-derived cells increases and aggregation of neural crest-derived cells decreases in LgDel CNgV. This change in cell-cell relationships was accompanied by altered proliferation of placode-derived cells at E9.5, and premature neurogenesis from neural crest-derived precursors, reflected by increased frequency of asymmetric neurogenic divisions for neural crest-derived precursors by E10.5. These early differences in LgDel CNgV genesis prefigure changes in sensory neuron differentiation and gene expression by P8, when early signs of cranial nerve dysfunction associated with pediatric dysphagia are observed in LgDel mice. Apparently, 22q11 deletion destabilizes CNgV sensory neuron genesis and differentiation by increasing variability in cell-cell interaction, proliferation, and sensory neuron differentiation. This early developmental divergence and its consequences may contribute to oropharyngeal dysfunction including suckling, feeding and swallowing disruptions at birth and additional orofacial sensory/motor deficits throughout life.

scholarly journals Exposure to arsenic during embryogenesis impairs olfactory sensory neuron differentiation and function into adulthood

Toxicology ◽  
2019 ◽  
Vol 420 ◽  
pp. 73-84 ◽  
Author(s):  
Dana B. Szymkowicz ◽  
Kaleigh C. Sims ◽  
Katey L. Schwendinger ◽  
Caroline M. Tatnall ◽  
Rhonda R. Powell ◽  
...  
Keyword(s):  
Sensory Neuron ◽  
Olfactory Sensory Neuron ◽  
Neuron Differentiation ◽  
And Function

scholarly journals Regulatory factor-X binding to mutant HLA-DRA promoter sequences

1991 ◽  
Vol 19 (6) ◽  
pp. 1243-1249 ◽  
Author(s):  
Susan L. Hasegawa ◽  
John H. Sloan ◽  
Walter Reith ◽  
Bernard Mach ◽  
Jeremy M Boss
Keyword(s):  
Factor X ◽  
Regulatory Factor ◽  
Promoter Sequences

The mechanisms and possible sites of acetylcholine release during chick primary sensory neuron differentiation

Life Sciences ◽  
2012 ◽  
Vol 91 (15-16) ◽  
pp. 783-788 ◽  
Author(s):  
V. Corsetti ◽  
C. Mozzetta ◽  
S. Biagioni ◽  
G. Augusti Tocco ◽  
A.M. Tata
Keyword(s):  
Sensory Neuron ◽  
Acetylcholine Release ◽  
Primary Sensory Neuron ◽  
Neuron Differentiation

scholarly journals Ets-1 activates the DRA promoter in B cells.

1994 ◽  
Vol 14 (11) ◽  
pp. 7314-7321 ◽  
Author(s):  
N Jabrane-Ferrat ◽  
B M Peterlin
Keyword(s):  
Major Histocompatibility Complex ◽  
B Cells ◽  
Dna Binding Proteins ◽  
Factor X ◽  
Regulatory Factor ◽  
Mobility Shift ◽  
The Core ◽  
Histocompatibility Complex ◽  
Ets Family ◽  
Electrophoretic Mobility Shift Assays

The X box in promoters of class II major histocompatibility complex genes plays a crucial role in the B-cell-specific and gamma interferon-inducible expression of these genes. The sequence TTCC is located in the pyrimidine tract which extends 5' to and partially overlaps the X box of the DRA promoter. This sequence resembles the core binding site for the Ets family of DNA-binding proteins. In this study, we demonstrate that mutations within the pyrimidine tract which change the TTCC motif, but do not affect the binding of regulatory factor X to the X box, decrease the activity of the DRA promoter in B cells. Furthermore, using electrophoretic mobility shift assays and cotransfection experiments, we demonstrate that Ets-1, but not Ets-2 or PU.1, functionally interacts with the pyrimidine tract and activates the DRA promoter.

scholarly journals Sensory neuron differentiation is regulated by notch signaling in the trigeminal placode

2010 ◽  
Vol 344 (2) ◽  
pp. 836-848 ◽  
Author(s):  
Rhonda N.T. Lassiter ◽  
Matthew K. Ball ◽  
Jason S. Adams ◽  
Brian T. Wright ◽  
Michael R. Stark
Keyword(s):  
Notch Signaling ◽  
Sensory Neuron ◽  
Neuron Differentiation ◽  
Trigeminal Placode

PACAP promotes sensory neuron differentiation: blockade by neurotrophic factors

2004 ◽  
Vol 25 (4) ◽  
pp. 629-641 ◽  
Author(s):  
Katherine M Nielsen ◽  
Martha Chaverra ◽  
Sharon J Hapner ◽  
Branden R Nelson ◽  
Valerie Todd ◽  
...  
Keyword(s):  
Sensory Neuron ◽  
Neurotrophic Factors ◽  
Neuron Differentiation

scholarly journals Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Crystal M. Gigante ◽  
Michele Dibattista ◽  
Frederick N. Dong ◽  
Xiaobin Zheng ◽  
Sibiao Yue ◽  
...  
Keyword(s):  
Gene Expression ◽  
Sensory Neuron ◽  
Olfactory Sensory Neuron ◽  
Specific Gene ◽  
Neuron Differentiation ◽  
Specific Gene Expression ◽  
Lamin B1 ◽  
Mature Neuron
Sign in / Sign up

Export Citation Format

Share Document