scholarly journals Future Leader to Watch – Fabrizio Alberti

Biology Open ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. bio057679
Keyword(s):  
Natural Product ◽  
Life Sciences ◽  
Early Career ◽  
Early Career Researchers ◽  
Natural Product Research ◽  
Senior Research Fellow ◽  
Recent Developments ◽  
Senior Research ◽  
Selection Of ◽  
Basidiomycete Fungi

ABSTRACTFuture Leader to Watch is a series of interviews with the first authors of a selection of Reviews published in Biology Open, helping early-career researchers promote themselves alongside their papers. Fabrizio Alberti is first author on ‘Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research’, published in BiO. Fabrizio is a Leverhulme Trust Early Career Fellow (Senior Research Fellow) at the School of Life Sciences and Department of Chemistry, University of Warwick, UK, investigating the discovery and biosynthetic characterisation of natural products made by fungi and bacteria.

scholarly journals First person – Kun Guo

Biology Open ◽  
2021 ◽  
Vol 10 (3) ◽  
Keyword(s):  
Color Change ◽  
Life Sciences ◽  
Early Career ◽  
First Person ◽  
Research Assistant ◽  
Thermal Dependence ◽  
Early Career Researchers ◽  
Takydromus Septentrionalis ◽  
Normal University ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Kun Guo is first author on ‘The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)’, published in BiO. Kun conducted the research described in this article while a PhD student in Xiang Ji's lab at Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Jiangsu, China. They are now research assistant in the lab of Xiang Ji at College of Life and Environmental Sciences, Wenzhou University, Zhejiang, China, and Jiangsu Key Laboratory for Biodiversity and Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu, China.

scholarly journals First person – Xiangchuan Wang

2021 ◽  
Vol 134 (3) ◽  
pp. jcs258445
Keyword(s):  
Caenorhabditis Elegans ◽  
Science And Technology ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
Research Scholar ◽  
Senior Research ◽  
Southern University ◽  
Selection Of ◽  
Meiosis I

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Xiangchuan Wang is first author on ‘Cortical recruitment of centralspindlin and RhoA effectors during meiosis I of Caenorhabditis elegans primary spermatocytes’, published in JCS. Xiangchuan is a Senior Research Scholar in the lab of Yu Chung Tse at the Southern University of Science and Technology, Shenzhen, P.R. China, investigating the generation of diversified gametes.

scholarly journals First person – Martín Baccino-Calace

Biology Open ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. bio055483
Keyword(s):  
Graduate Student ◽  
Life Sciences ◽  
Early Career ◽  
First Person ◽  
Cell Type ◽  
Synaptic Physiology ◽  
Early Career Researchers ◽  
Cell Type Specific ◽  
University Of Zurich ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Martín Baccino-Calace is first author on ‘Compartment and cell-type specific hypoxia responses in the developing Drosophila brain’, published in BiO. Martín conducted the research described in this article while a master's student in Rafael Cantera's lab at the Department of Neurodevelopment Biology, IIBCE, Uruguay. He is now a graduate student in the lab of Martin Müller at the Department of Molecular Life Sciences, University of Zurich, Switzerland, investigating synaptic physiology.

scholarly journals First person – Shun Kato

2021 ◽  
Vol 134 (22) ◽  
Keyword(s):  
Mammalian Cells ◽  
Life Sciences ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
Organelle Communication ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Shun Kato is first author on ‘ Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms’, published in JCS. Shun is a master's student in the lab of Mitsuo Tagaya at the School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Japan, investigating organelle communication in mammalian cells.

scholarly journals First person – Vibhu Prasad

2021 ◽  
Vol 134 (5) ◽  
Keyword(s):  
Life Sciences ◽  
Early Career ◽  
First Person ◽  
Molecular Virology ◽  
Genome Variability ◽  
Early Career Researchers ◽  
Research Associate ◽  
Cellular Factors ◽  
University Of Zurich ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Vibhu Prasad is co-first author on ‘Cell-to-cell and genome-to-genome variability of adenovirus transcription tuned by the cell cycle’, published in JCS. Vibhu conducted the research described in this article while a Research Associate/bridging postdoc in Professor Urs Greber's lab at Department of Molecular Life Sciences, University of Zurich, Switzerland. He is now a postdoc in the lab of Professor Ralf Bartenschlager at the Department of Infectious Diseases, Molecular Virology, University of Heidelberg, Germany, working on identification of cellular factors and processes required for flavivirus and SARS-CoV-2 infection.

scholarly journals First person – Kalyanasundaram Parthasarathy

Biology Open ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. bio058685
Keyword(s):  
Biological Sciences ◽  
Brain Function ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
Tata Institute ◽  
Research Associate ◽  
Senior Research ◽  
Fundamental Research ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Kalyanasundaram Parthasarathy is first author on ‘Spatial odor discrimination in the hawkmoth, Manduca sexta (L.)’, published in BiO. He conducted the research described in this article while a Senior Research Associate in Professor Mark A Willis's lab at the Department of Biology, Case Western Reserve University, Cleveland, Ohio, USA. He is now a Postdoc in the lab of Professor Sanjay P Sane at National Centre for Biological Sciences at the Tata Institute of Fundamental Research, Bangalore, India, investigating how animals use sensory cues to navigate, the related behaviours and the underlying brain function.

scholarly journals Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

Biology Open ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. bio056010
Author(s):  
Fabrizio Alberti ◽  
Saraa Kaleem ◽  
Jack A. Weaver
Keyword(s):  
Natural Products ◽  
Natural Product ◽  
Gene Clusters ◽  
Bioactive Metabolites ◽  
Network Analyses ◽  
Natural Product Research ◽  
Technological Advances ◽  
Long Read ◽  
Recent Developments ◽  
Basidiomycete Fungi

ABSTRACTBasidiomycota are a large and diverse phylum of fungi. They can make bioactive metabolites that are used or have inspired the synthesis of antibiotics and agrochemicals. Terpenoids are the most abundant class of natural products encountered in this taxon. Other natural product classes have been described, including polyketides, peptides, and indole alkaloids. The discovery and study of natural products made by basidiomycete fungi has so far been hampered by several factors, which include their slow growth and complex genome architecture. Recent developments of tools for genome and metabolome studies are allowing researchers to more easily tackle the secondary metabolome of basidiomycete fungi. Inexpensive long-read whole-genome sequencing enables the assembly of high-quality genomes, improving the scaffold upon which natural product gene clusters can be predicted. CRISPR/Cas9-based engineering of basidiomycete fungi has been described and will have an important role in linking natural products to their genetic determinants. Platforms for the heterologous expression of basidiomycete genes and gene clusters have been developed, enabling natural product biosynthesis studies. Molecular network analyses and publicly available natural product databases facilitate data dereplication and natural product characterisation. These technological advances combined are prompting a revived interest in natural product discovery from basidiomycete fungi.This article has an associated Future Leader to Watch interview with the first author of the paper.

scholarly journals First person – Eike Mahlandt

2021 ◽  
Vol 134 (17) ◽  
Keyword(s):  
Vascular Endothelial Cells ◽  
Fluorescent Microscopy ◽  
Life Sciences ◽  
Early Career ◽  
First Person ◽  
Vascular Endothelial ◽  
Molecular Tools ◽  
Protein Activity ◽  
Early Career Researchers ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Eike Mahlandt is first author on ‘ Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor’, published in JCS. Eike is a PhD candidate in the lab of Joachim Goedhart at Department Molecular Cytology, Swammerdam Institute for Life Sciences, Amsterdam, The Netherlands, where she develops molecular tools to study protein activity in real-time in vascular endothelial cells using fluorescent microscopy.

scholarly journals First person – Pragya Chandrakar

2021 ◽  
Vol 134 (5) ◽  
pp. jcs258532
Keyword(s):  
New York ◽  
Immune Cell ◽  
Albert Einstein College ◽  
Albert Einstein ◽  
Early Career ◽  
First Person ◽  
Research Fellow ◽  
Senior Research Fellow ◽  
Senior Research ◽  
Selection Of

ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Pragya Chandrakar is first author on ‘Jagged–Notch-mediated divergence of immune cell crosstalk maintains the anti-inflammatory response in visceral leishmaniasis’, published in JCS. Pragya conducted the research described in this article while a Senior Research Fellow in Dr Susanta Kar's lab at the CSIR Central Drug Research Institute, Lucknow, India. She is now a Postdoctoral Research Fellow in the lab of Dr John Chan at Albert Einstein College of Medicine, New York, USA, investigating the different possible mechanisms by which foreign pathogens breach the immune system.

scholarly journals First person – Bharath Srinivasan

2021 ◽  
Vol 134 (10) ◽  
Keyword(s):  
Nucleic Acids ◽  
Stress Granules ◽  
Early Career ◽  
First Person ◽  
Early Career Researchers ◽  
Senior Research Scientist ◽  
Senior Research ◽  
Mechanistic Biology ◽  
Innate Ability ◽  
Selection Of

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Bharath Srinivasan is co-first author on ‘ Enrichment of Zα domains at cytoplasmic stress granules is due to their innate ability to bind to nucleic acids’, published in JCS. Bharath conducted the research described in this article while a Marie Sklodowska-Curie Individual Fellow in Alekos Athanasiadis's lab at the Instituto Gulbenkian de Ciência, Oeiras, Portugal. He is now a senior research scientist at AstraZeneca in Cambridge, UK, investigating mechanistic biology and enzymology.

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