scholarly journals Tree shrew (Tupaia belangeri chinensis), a novel non-obese animal model of non-alcoholic fatty liver disease

Biology Open ◽  
2016 ◽  
Vol 5 (10) ◽  
pp. 1545-1552 ◽  
Author(s):  
Linqiang Zhang ◽  
Xiaoyun Wu ◽  
Shasha Liao ◽  
Yunhai Li ◽  
Zhiguo Zhang ◽  
...  
Keyword(s):  
Animal Model ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Tree Shrew ◽  
Alcoholic Fatty Liver ◽  
Obese Animal ◽  
Tupaia Belangeri ◽  
Alcoholic Fatty Liver Disease

scholarly journals Murine models provide insight to the development of non-alcoholic fatty liver disease

2015 ◽  
Vol 28 (2) ◽  
pp. 133-142 ◽  
Author(s):  
D. T. Reid ◽  
B. Eksteen
Keyword(s):  
Animal Model ◽  
Liver Disease ◽  
Animal Models ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Treatment Strategies ◽  
Alcoholic Fatty Liver ◽  
Advantages And Disadvantages ◽  
The Metabolic Syndrome ◽  
Alcoholic Fatty Liver Disease

AbstractAssociated with the obesity epidemic, non-alcoholic fatty liver disease (NAFLD) has become the leading liver disease in North America. Approximately 30 % of patients with NAFLD may develop non-alcoholic steatohepatitis (NASH) that can lead to cirrhosis and hepatocellular carcinoma (HCC). Frequently animal models are used to help identify underlying factors contributing to NAFLD including insulin resistance, dysregulated lipid metabolism and mitochondrial stress. However, studying the inflammatory, progressive nature of NASH in the context of obesity has proven to be a challenge in mice. Although the development of effective treatment strategies for NAFLD and NASH is gaining momentum, the field is hindered by a lack of a concise animal model that reflects the development of liver disease during obesity and the metabolic syndrome. Therefore, selecting an animal model to study NAFLD or NASH must be done carefully to ensure the optimal application. The most widely used animal models have been reviewed highlighting their advantages and disadvantages to studying NAFLD and NASH specifically in the context of obesity.

Psammomys obesus (sand rat), a new animal model of non-alcoholic fatty liver disease

2006 ◽  
Vol 72 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Maximo Maislos ◽  
Vitali Medvedovskv ◽  
Ignacio Sztarkier ◽  
Arieh Yaari ◽  
Emanuel Sikuler
Keyword(s):  
Animal Model ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Psammomys Obesus ◽  
Sand Rat ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

scholarly journals A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer

2016 ◽  
Vol 65 (3) ◽  
pp. 579-588 ◽  
Author(s):  
Amon Asgharpour ◽  
Sophie C. Cazanave ◽  
Tommy Pacana ◽  
Mulugeta Seneshaw ◽  
Robert Vincent ◽  
...  
Keyword(s):  
Animal Model ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Hepatocellular Cancer ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

A novel animal model of metabolic syndrome with non-alcoholic fatty liver disease and skin inflammation

2014 ◽  
Vol 53 (8) ◽  
pp. 1110-1117 ◽  
Author(s):  
Nagaraj M. Kulkarni ◽  
Mallikarjun S. Jaji ◽  
Pranesha Shetty ◽  
Yeshwant V. Kurhe ◽  
Shilpee Chaudhary ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Animal Model ◽  
Liver Disease ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Skin Inflammation ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease
Sign in / Sign up

Export Citation Format

Share Document