Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability

Emma L. Wilkinson; James E. Sidaway; Michael J. Cross

doi:10.1242/bio.020362

Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability

Biology Open ◽

10.1242/bio.020362 ◽

2016 ◽

Vol 5 (10) ◽

pp. 1362-1370 ◽

Cited By ~ 24

Author(s):

Emma L. Wilkinson ◽

James E. Sidaway ◽

Michael J. Cross

Keyword(s):

Endothelial Cell ◽

Microvascular Endothelial Cell ◽

Drug Permeability ◽

Barrier Formation ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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Increased myocardial stiffness activates cardiac microvascular endothelial cell via VEGF paracrine signaling in cardiac hypertrophy

Journal of Molecular and Cellular Cardiology ◽

10.1016/j.yjmcc.2018.08.014 ◽

2018 ◽

Vol 122 ◽

pp. 140-151 ◽

Cited By ~ 12

Author(s):

Jian Shen ◽

Yao Xie ◽

Zhenjie Liu ◽

Shuning Zhang ◽

Yaping Wang ◽

...

Keyword(s):

Endothelial Cell ◽

Cardiac Hypertrophy ◽

Microvascular Endothelial Cell ◽

Paracrine Signaling ◽

Myocardial Stiffness ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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Macrophages Aggravate Hypoxia-Induced Cardiac Microvascular Endothelial Cell Injury via Peroxynitrite: Protection by Tongxinluo

Cell Communication & Adhesion ◽

10.3109/15419061.2016.1155565 ◽

2015 ◽

Vol 22 (2-6) ◽

pp. 39-47 ◽

Cited By ~ 4

Author(s):

Xiujuan Wang ◽

Kun Liu ◽

Bin Li ◽

Yanning Li ◽

Kaiwei Ye ◽

...

Keyword(s):

Endothelial Cell ◽

Cell Injury ◽

Microvascular Endothelial Cell ◽

Endothelial Cell Injury ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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Methylation-dependent transcriptional repression of RUNX3 by KCNQ1OT1 regulates mouse cardiac microvascular endothelial cell viability and inflammatory response following myocardial infarction

The FASEB Journal ◽

10.1096/fj.201900310r ◽

2019 ◽

Vol 33 (12) ◽

pp. 13145-13160 ◽

Cited By ~ 1

Author(s):

Yanbin Wang ◽

Xudong Yang ◽

An Jiang ◽

Wei Wang ◽

Jian Li ◽

...

Keyword(s):

Myocardial Infarction ◽

Endothelial Cell ◽

Inflammatory Response ◽

Cell Viability ◽

Transcriptional Repression ◽

Microvascular Endothelial Cell ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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The CXCL10/CXCR3 axis promotes cardiac microvascular endothelial cell migration via the p38/FAK pathway in a proliferation-independent manner

Experimental and Molecular Pathology ◽

10.1016/j.yexmp.2016.01.010 ◽

2016 ◽

Vol 100 (2) ◽

pp. 257-265 ◽

Cited By ~ 8

Author(s):

Jing-Bo Xia ◽

Cheng-Zhou Mao ◽

Zhuo-Ying Chen ◽

Guang-Hui Liu ◽

Hai-Yan Wu ◽

...

Keyword(s):

Cell Migration ◽

Endothelial Cell ◽

Endothelial Cell Migration ◽

Microvascular Endothelial Cell ◽

Independent Manner ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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GW26-e2445 Protective effects and its mechanism of Helix B-surface peptide against cardiac microvascular endothelial cell injury induced by ischemia / reperfusion

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2015.06.1231 ◽

2015 ◽

Vol 66 (16) ◽

pp. C54

Author(s):

Chen Wang ◽

Rui Si ◽

Mingming Zhang ◽

Rongqing Zhang ◽

Haichang Wang

Keyword(s):

Endothelial Cell ◽

Cell Injury ◽

Ischemia Reperfusion ◽

Microvascular Endothelial Cell ◽

Protective Effects ◽

Endothelial Cell Injury ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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MicroRNA‐128 confers protection against cardiac microvascular endothelial cell injury in coronary heart disease via negative regulation of IRS1

Journal of Cellular Physiology ◽

10.1002/jcp.28025 ◽

2019 ◽

Vol 234 (8) ◽

pp. 13452-13463 ◽

Cited By ~ 5

Author(s):

Ping Yan ◽

Chen Sun ◽

Jiale Ma ◽

Zhigang Jin ◽

Rui Guo ◽

...

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Endothelial Cell ◽

Cell Injury ◽

Negative Regulation ◽

Microvascular Endothelial Cell ◽

Endothelial Cell Injury ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2019.02.090 ◽

2019 ◽

Vol 511 (2) ◽

pp. 476-481 ◽

Cited By ~ 1

Author(s):

Kun Hu ◽

Qian Wan

Keyword(s):

Endothelial Cell ◽

Microvascular Endothelial Cell ◽

Physiological Conditions ◽

Cell Functions ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction

Theranostics ◽

10.7150/thno.47021 ◽

2021 ◽

Vol 11 (1) ◽

pp. 268-291

Author(s):

Zhaofu Liao ◽

Yilin Chen ◽

Chuncui Duan ◽

Kuikui Zhu ◽

Ruijin Huang ◽

...

Keyword(s):

Myocardial Infarction ◽

Endothelial Cell ◽

Cell Apoptosis ◽

Microvascular Endothelial Cell ◽

Endothelial Cell Apoptosis ◽

Microvascular Endothelial ◽

Exosomal Mirna ◽

Cardiac Microvascular Endothelial Cell

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Ulinastatin protects against lipopolysaccharide-induced cardiac microvascular endothelial cell dysfunction via downregulation of lncRNA MALAT1 and EZH2 in sepsis

International Journal of Molecular Medicine ◽

10.3892/ijmm.2017.2920 ◽

2017 ◽

Vol 39 (5) ◽

pp. 1269-1276 ◽

Cited By ~ 25

Author(s):

Zhaoxia Yu ◽

Aisa Rayile ◽

Xiangyang Zhang ◽

Ying Li ◽

Qiang Zhao

Keyword(s):

Endothelial Cell ◽

Microvascular Endothelial Cell ◽

Endothelial Cell Dysfunction ◽

Cell Dysfunction ◽

Lncrna Malat1 ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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Remifentanil pretreatment ameliorates H/R-induced cardiac microvascular endothelial cell dysfunction by regulating the PI3K/Akt/HIF-1α signaling pathway

Bioengineered ◽

10.1080/21655979.2021.1969843 ◽

2021 ◽

Vol 12 (1) ◽

pp. 7872-7881

Author(s):

Xiaojun Li ◽

Zhenping Gui ◽

Huizi Liu ◽

Shaojie Qian ◽

Yanan Jia ◽

...

Keyword(s):

Endothelial Cell ◽

Signaling Pathway ◽

Microvascular Endothelial Cell ◽

Endothelial Cell Dysfunction ◽

Cell Dysfunction ◽

Microvascular Endothelial ◽

Cardiac Microvascular Endothelial Cell

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