scholarly journals No discrimination shock avoidance with sequential presentation of stimuli but shore crabs still reduce shock exposure

Biology Open ◽  
2016 ◽  
Vol 5 (7) ◽  
pp. 883-888 ◽  
Author(s):  
Barry Magee ◽  
Robert W. Elwood
2020 ◽  
Author(s):  
Matthew Philip Kaesler ◽  
John C Dunn ◽  
Keith Ransom ◽  
Carolyn Semmler

The debate regarding the best way to test and measure eyewitness memory has dominated the eyewitness literature for more than thirty years. We argue that to resolve this debate requires the development and application of appropriate measurement models. In this study we develop models of simultaneous and sequential lineup presentations and use these to compare the procedures in terms of discriminability and response bias. We tested a key prediction of the diagnostic feature detection hypothesis that discriminability should be greater for simultaneous than sequential lineups. We fit the models to the corpus of studies originally described by Palmer and Brewer (2012, Law and Human Behavior, 36(3), 247-255) and to data from a new experiment. The results of both investigations showed that discriminability did not differ between the two procedures, while responses were more conservative for sequential presentation compared to simultaneous presentation. We conclude that the two procedures do not differ in the efficiency with which they allow eyewitness memory to be expressed. We discuss the implications of this for the diagnostic feature detection hypothesis and other sequential lineup procedures used in current jurisdictions.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Shuoshuo Li ◽  
Yajin Liao ◽  
Yuan Dong ◽  
Xiaoheng Li ◽  
Jun Li ◽  
...  

Abstract Background Alteration of immune status in the central nervous system (CNS) has been implicated in the development of post-traumatic stress disorder (PTSD). However, the nature of overall changes in brain immunocyte landscape in PTSD condition remains unclear. Methods We constructed a mouse PTSD model by electric foot-shocks followed by contextual reminders and verified the PTSD-related symptoms by behavior test (including contextual freezing test, open-field test, and elevated plus maze test). We examined the immunocyte panorama in the brains of the naïve or PTSD mice by using single-cell mass cytometry. Microglia number and morphological changes in the hippocampus, prefrontal cortex, and amygdala were analyzed by histopathological methods. The gene expression changes of those microglia were detected by quantitative real-time PCR. Genetic/pharmacological depletion of microglia or minocycline treatment before foot-shocks exposure was performed to study the role of microglia in PTSD development and progress. Results We found microglia are the major brain immune cells that respond to PTSD. The number of microglia and ratio of microglia to immunocytes was significantly increased on the fifth day of foot-shock exposure. Furthermore, morphological analysis and gene expression profiling revealed temporal patterns of microglial activation in the hippocampus of the PTSD brains. Importantly, we found that genetic/pharmacological depletion of microglia or minocycline treatment before foot-shock exposure alleviated PTSD-associated anxiety and contextual fear. Conclusion Our results demonstrated a critical role for microglial activation in PTSD development and a potential therapeutic strategy for the clinical treatment of PTSD in the form of microglial inhibition.


2015 ◽  
Vol 128 (2) ◽  
pp. 173 ◽  
Author(s):  
Finley ◽  
Roediger ◽  
Hughes ◽  
Wahlheim ◽  
Jacoby

1986 ◽  
Vol 95 (4) ◽  
pp. 437-445 ◽  
Author(s):  
D R Joel ◽  
P J Sanjeeva Raj ◽  
R Raghavan
Keyword(s):  

1973 ◽  
Vol 25 (3) ◽  
pp. 413-423 ◽  
Author(s):  
Graham M. Davies ◽  
J. E. Milne ◽  
B. J. Glennie

Ten-year-old children who were shown pictures of objects immediately preceded by the object's name recalled the material no better than those exposed to the names of the stimuli alone. Both conditions yielded significantly poorer retention than those in which pictures alone were presented or pictures followed by their names. A second study replicated this result. In addition this demonstrated, by a picture and name recognition task, that the effects could not be due to subjects in the “name prior to picture” condition ignoring the pictorial component. These results were interpreted as contradicting the “double encoding” explanation of the superiority of pictures to names in free recall. Parallel visual and verbal encoding of a pictured object does not facilitate retention unless the verbal cue is actively elicited from the subject by the stimulus. The implications of this result for other studies which have employed either simultaneous or sequential presentation of pictures and names are briefly discussed.


Sign in / Sign up

Export Citation Format

Share Document