scholarly journals Effects of Rapid Weight Loss on Systemic and Adipose Tissue Inflammation and Metabolism in Obese Postmenopausal Women

2017 ◽  
Vol 1 (6) ◽  
pp. 625-637 ◽  
Author(s):  
José O. Alemán ◽  
Neil M. Iyengar ◽  
Jeanne M. Walker ◽  
Ginger L. Milne ◽  
Joel Correa Da Rosa ◽  
...  
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Postmenopausal Women ◽  
Rapid Weight Loss ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

2032-P: Adipose Tissue Inflammation after Weight Loss

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2032-P
Author(s):  
ANA E. ESPINOSA DE YCAZA ◽  
ESBEN SØNDERGAARD ◽  
MARIA MORGAN-BATHKE ◽  
DANAE A. DELIVANIS ◽  
BARBARA G. CARRANZA LEON ◽  
...  
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

scholarly journals Adipose tissue inflammation contributes to body weight loss induced by experimental chronic food allergy in mice

2011 ◽  
Vol 1 (S1) ◽  
Author(s):  
Denise Carmona Cara ◽  
Luana PA Dourado ◽  
Mria LM Noviello ◽  
Debora M Alvarenga ◽  
Gustavo B Menezes ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Adipose Tissue ◽  
Food Allergy ◽  
Body Weight Loss ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

scholarly journals Experimental food allergy leads to adipose tissue inflammation, systemic metabolic alterations and weight loss in mice

2011 ◽  
Vol 270 (2) ◽  
pp. 198-206 ◽  
Author(s):  
Luana Pereira Antunes Dourado ◽  
Maria de Lourdes Meirelles Noviello ◽  
Débora Moreira Alvarenga ◽  
Zélia Menezes ◽  
Denise Alves Perez ◽  
...  
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Food Allergy ◽  
Adipose Tissue Inflammation ◽  
Metabolic Alterations ◽  
Tissue Inflammation

scholarly journals Increased Interleukin-32 Levels in Obesity Promote Adipose Tissue Inflammation and Extracellular Matrix Remodeling: Effect of Weight Loss

Diabetes ◽  
2016 ◽  
Vol 65 (12) ◽  
pp. 3636-3648 ◽  
Author(s):  
Victoria Catalán ◽  
Javier Gómez-Ambrosi ◽  
Amaia Rodríguez ◽  
Beatriz Ramírez ◽  
Víctor Valentí ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Weight Loss ◽  
Adipose Tissue ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

Metabolic inflammation: role of cytokines in the crosstalk between adipose tissue and liver

2013 ◽  
Vol 91 (11) ◽  
pp. 867-872 ◽  
Author(s):  
Romana R. Gerner ◽  
Verena Wieser ◽  
Alexander R. Moschen ◽  
Herbert Tilg
Keyword(s):  
Morbid Obesity ◽  
Adipose Tissue ◽  
Inflammatory Cytokines ◽  
Severe Obesity ◽  
The Body ◽  
Rapid Weight Loss ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation ◽  
Metabolic Inflammation ◽  
Pro Inflammatory Cytokines

The innate immune system and its major mediators, i.e., cytokines, are increasingly recognized as being of crucial importance in metabolic inflammation as observed in morbid obesity and type 2 diabetes (T2D). Morbid obesity is commonly associated with adipose tissue inflammation. Adipose tissue inflammation is characterized by an increased expression of various pro-inflammatory cytokines such as tumor necrosis factor-alpha, interleukin-1 and -6, and by a rather heterogenous cellular infiltrate including monocytes/macrophages, neutrophils, B lymphocytes, T lymphocytes, and others. It has been demonstrated that in patients with severe obesity and fatty liver disease, expression of these pro-inflammatory cytokines in adipose tissue is 100–1000 times higher compared with that in the liver. Therefore, the adipose tissue can be considered in the state of severe obesity as the “cytokine factory” of the body. Rapid weight loss almost entirely eliminates pro-inflammatory cytokines in the adipose tissue, and therefore provides a very potent anti-inflammatory strategy. In conclusion, there is increasing evidence that peripheral tissues such as the adipose tissue may affect disease processes in target organs such as the liver, pancreas, heart, or blood vessels, and may therefore significantly contribute to chronic inflammation as observed in obesity and T2D.

Flavonoids in adipose tissue inflammation and atherosclerosis: one arrow, two targets

2020 ◽  
Vol 134 (12) ◽  
pp. 1403-1432 ◽  
Author(s):  
Manal Muin Fardoun ◽  
Dina Maaliki ◽  
Nabil Halabi ◽  
Rabah Iratni ◽  
Alessandra Bitto ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fruits And Vegetables ◽  
Metabolic Diseases ◽  
Therapeutic Agents ◽  
Adipose Tissue Inflammation ◽  
Cellular Mechanisms ◽  
Tissue Inflammation ◽  
Cholesterol Levels ◽  
Naturally Occurring ◽  
Pro Inflammatory Cytokines

Abstract Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic diseases. Several studies corroborated an inverse relationship between flavonoid consumption and cardiovascular disease (CVD) or adipose tissue inflammation (ATI). Flavonoids exert their anti-atherogenic effects by increasing nitric oxide (NO), reducing reactive oxygen species (ROS), and decreasing pro-inflammatory cytokines. In addition, flavonoids alleviate ATI by decreasing triglyceride and cholesterol levels, as well as by attenuating inflammatory mediators. Furthermore, flavonoids inhibit synthesis of fatty acids and promote their oxidation. In this review, we discuss the effect of the main classes of flavonoids, namely flavones, flavonols, flavanols, flavanones, anthocyanins, and isoflavones, on atherosclerosis and ATI. In addition, we dissect the underlying molecular and cellular mechanisms of action for these flavonoids. We conclude by supporting the potential benefit for flavonoids in the management or treatment of CVD; yet, we call for more robust clinical studies for safety and pharmacokinetic values.

The Effect of Saxagliptin on Adipose Tissue Inflammation in Overweight and Obese Nondiabetic Subjects

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1212-P ◽  
Author(s):  
JURAJ KOSKA ◽  
TRACY OSREDKAR ◽  
D'SOUZA KAREN ◽  
SANDEEP SINHA ◽  
CHRISTIAN MEYER ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation

Insulin Sensitizing Effects of Vitamin D Mediated through Reduced Adipose Tissue Inflammation and Fibrosis

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 39-OR
Author(s):  
ERIC LONTCHI-YIMAGOU ◽  
SONA KANG ◽  
KEHAO ZHANG ◽  
AKANKASHA GOYAL ◽  
JEE YOUNG YOU ◽  
...  
Keyword(s):  
Vitamin D ◽  
Adipose Tissue ◽  
Adipose Tissue Inflammation ◽  
Tissue Inflammation
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