scholarly journals Evaluation of Circulating Determinants of Beta-Cell Function in Women With and Without Gestational Diabetes

2016 ◽  
Vol 101 (7) ◽  
pp. 2683-2691 ◽  
Author(s):  
Ravi Retnakaran ◽  
Chang Ye ◽  
Caroline K. Kramer ◽  
Philip W. Connelly ◽  
Anthony J. Hanley ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function

scholarly journals Longitudinal changes in insulin sensitivity and beta cell function between women with and without a history of gestational diabetes mellitus

Diabetologia ◽  
2013 ◽  
Vol 56 (12) ◽  
pp. 2753-2760 ◽  
Author(s):  
Anny H. Xiang ◽  
Miwa Takayanagi ◽  
Mary Helen Black ◽  
Enrique Trigo ◽  
Jean M. Lawrence ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Sensitivity ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Longitudinal Changes ◽  
History Of

scholarly journals Glucose Intolerance after a Recent History of Gestational Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Katrien Benhalima ◽  
Liesbeth Leuridan ◽  
Peggy Calewaert ◽  
Roland Devlieger ◽  
Johan Verhaeghe ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Gestational Diabetes ◽  
Beta Cell ◽  
Glucose Intolerance ◽  
Beta Cell Function ◽  
Cell Function ◽  
Screening Strategy ◽  
Recent History ◽  
Sensitivity Index ◽  
History Of

Aim. Our aim was to evaluate the uptake of our current screening strategy postpartum and the risk factors for glucose intolerance in women with a recent history of gestational diabetes (GDM).Methods. Retrospective analysis of files of women with a recent history of GDM diagnosed with the Carpenter and Coustan criteria from 01-01-2010 till 31-12-2013. Multivariable logistic regression was used to adjust for confounders.Results. Of all 231 women with a recent history of GDM, 21.4% (46) did not attend the scheduled postpartum OGTT. Of the women tested, 39.1% (66) had glucose intolerance and 5.3% (9) had diabetes. These women were more often overweight (39.7% versus 25.3%,P= 0.009), were more often treated with basal-bolus insulin injections (52.0% versus 17.4%,P= 0.032), and had a lower beta-cell function and lower insulin sensitivity, remaining significant after adjustment for age, BMI, and ethnicity (insulin secretion sensitivity index-2 (ISSI-2) in pregnancy 1.5 ± 0.5 versus 1.7 ± 0.4,P= 0.029; ISSI-2 postpartum 1.5 (1.2–1.9) versus 2.2 (1.8–2.6),P= 0.020; Matsuda index postpartum 3.8 (2.6–6.2) versus 6.0 (4.3–8.8),P= 0.021).Conclusion. Glucose intolerance is frequent in early postpartum and these women have a lower beta-cell function and lower insulin sensitivity. One fifth of women did not attend the scheduled OGTT postpartum.

scholarly journals Environmental pollutants and beta cell function: relevance for type 1 and gestational diabetes

Diabetologia ◽  
2011 ◽  
Vol 54 (12) ◽  
pp. 3168-3169 ◽  
Author(s):  
S. G. Howard ◽  
J. J. Heindel ◽  
K. A. Thayer ◽  
M. Porta
Keyword(s):  
Gestational Diabetes ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Environmental Pollutants

scholarly journals Impact of daily incremental change in environmental temperature on beta cell function and the risk of gestational diabetes in pregnant women

Diabetologia ◽  
2018 ◽  
Vol 61 (12) ◽  
pp. 2633-2642 ◽  
Author(s):  
Ravi Retnakaran ◽  
Chang Ye ◽  
Caroline K. Kramer ◽  
Anthony J. Hanley ◽  
Philip W. Connelly ◽  
...  
Keyword(s):  
Gestational Diabetes ◽  
Beta Cell ◽  
Pregnant Women ◽  
Beta Cell Function ◽  
Environmental Temperature ◽  
Cell Function ◽  
Incremental Change
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