scholarly journals Exposure to Famine in Early Life and Nonalcoholic Fatty Liver Disease in Adulthood

2016 ◽  
Vol 101 (5) ◽  
pp. 2218-2225 ◽  
Author(s):  
Ningjian Wang ◽  
Yi Chen ◽  
Zhiyuan Ning ◽  
Qin Li ◽  
Bing Han ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Early Life ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver

scholarly journals Developmental Programming of Nonalcoholic Fatty Liver Disease: The Effect of Early Life Nutrition on Susceptibility and Disease Severity in Later Life

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Minglan Li ◽  
Clare M. Reynolds ◽  
Stephanie A. Segovia ◽  
Clint Gray ◽  
Mark H. Vickers
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Early Life ◽  
Fatty Liver Disease ◽  
Maternal Obesity ◽  
Later Life ◽  
Developmental Programming ◽  
Nonalcoholic Fatty Liver ◽  
Increased Risk

Nonalcoholic fatty liver disease (NAFLD) is fast becoming the most common liver disease globally and parallels rising obesity rates. The developmental origins of health and disease hypothesis have linked alterations in the early life environment to an increased risk of metabolic disorders in later life. Altered early life nutrition, in addition to increasing risk for the development of obesity, type 2 diabetes, and cardiovascular disease in offspring, is now associated with an increased risk for the development of NAFLD. This review summarizes emerging research on the developmental programming of NAFLD by both maternal obesity and undernutrition with a particular focus on the possible mechanisms underlying the development of hepatic dysfunction and potential strategies for intervention.

Early life famine exposure, adulthood obesity patterns and the risk of nonalcoholic fatty liver disease

2020 ◽  
Vol 40 (11) ◽  
pp. 2694-2705
Author(s):  
Hongyan Qi ◽  
Chunyan Hu ◽  
Shuangyuan Wang ◽  
Yi Zhang ◽  
Rui Du ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Early Life ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
Famine Exposure
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